Крок 2 · Медицина 2018 · Англійська

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01

A patient with Morgagni-Adams-Stokes syndrome has fainted when walking up the stairs. The skin is pale, the pupils are dilated, tonoclonic spasms are observed, rib cage is immobile. Make the diagnosis:

A Social death
B Biological death
C Preagony
D Agony
E Clinical death
02

A 32-year-old welder complains of weakness and fever. His illness initially presented as tonsillitis one month earlier. On examination: temperature - 38.9°C, respirations - 24/min., pulse - 100/min., blood pressure - 100/70 mm Hg, hemorrhages on the legs, enlargement of the lymph nodes. Complete blood count shows Hb- 70 g/L, RBC- 2.2×10¹²/L, WBC- 3.0×10⁹/L with 32% of blasts, 1% of eosinophiles, 3% of bands, 36% of segments, 20% of lymphocytes, and 8% of monocytes, ESR- 47 mm/hour. What is the cause of anemia in this case?

A Acute leukemia
B Chronic hemolytic anemia
C B₁₂-de?cient anemia
D Aplastic anema
E Chronic lympholeukemia
03

After a 5-day-long celebration of his daughter's wedding a 65-year-old patient ”saw” in his yard many cats, chickens, and rats. He tried to chase them away, but was scared off when the animals started scolding him and tried to harm him. What is the likely diagnosis?

A Senile psychosis
B Reactive hallucinosis
C Delirium tremens
D Schizophrenia
E Organic brain syndrome
04

A regional cardiologist is given a task to develop a plan for preventive measures aimed at decreasing cardiovascular mortality rates. What measures should be planned for secondary prevention?

A Prevention of recurrences and complications
B Prevention of diseases
C Referring patients for sanatorium-and-spa treatment
D Optimization of lifestyle and living conditions
E Referring patients for inpatient treatment
05

During physical exertion a man suddenly developed acute chest pain on the right and dyspnea. Objectively he assumes forced halfsitting position in the bed, presents with diffuse cyanosis, resting tachypnea of 38/min., the right side of the thorax is enlarged and does not participate in the respiratory process; percussion on the right reveals tympanic resonance and absence of respiration.What is the most likely diagnosis in this case?

A Lobar pneumonia
B Hemothorax
C Spontaneous pneumothorax
D Acute pleurisy
E Pulmonary embolism
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06

A 34-year-old man on the 3rd day of ceftriaxone treatment for acute otitis (daily dosage - 2 grams) developed diarrhea occurring 5-6 times per day. Feces are without mucus or blood admixtures. Temperature is 36.6°C. Gregersen reaction (occult blood in feces) is negative. Stool culture detected no pathogenic germs. What is the most likely cause of diarrhea in this case?

A Crohn's disease (regional enteritis)
B Intestinal dysbiosis
C Ulcerative colitis
D Bacterial overgrowth syndrome
E Antibiotic-associated diarrhea
07

A 24-year-old patient visited a doctor complaining of enlargement of his submaxillary lymph nodes. Objectively: submaxillary, axillary and inguinal lymph nodes are enlarged. Chest X-ray shows: enlarged lymph nodes of mediastinum. Blood test: erythrocytes 3.4 × 10¹²/L, Hb- 100 g/L, blood colour index - 0.88, platelets - 190 × 10⁹/L, leucocytes 7.5 × 10⁹/L, eosinophiles - 8%, band neutrophiles - 2%, segmented neutrophiles - 67%, lymphocytes - 23%, ESR - 22 mm/hour. What test must be prescribed to verify the cause of lymphadenopathy?

A Mediastinum tomography
B Sternal puncture
C Open biopsy of the lymph nodes
D Puncture biopsy of the lymph nodes
E Abdominal US
08

During medical examination a cadet in the naval college was detected to have a painless dense ulcer 1.5x0.5 in size in his perianal area at the 2 o'clock position. The ulcer ?oor resembles ”old fat”. What is the provisional diagnosis?

A Rectal ?ssure
B Rectal ?stula
C Hard syphilitic chancre of the rectum
D Anal crypt suppuration
E Anal cancer
09

A 7-year-old boy has severe pulmonary mucoviscidosis (cystic ?brosis). He complains of dyspnea and blood expectoration. Objectively he presents with lagging physical development, acrocyanosis, hepatomegaly, drumstick ?ngers, and nail plates resembling a”clockface.”Provisional diagnosis of chronic pulmonary heart disease is made. What examination would be the most informative for diagnosis con?rmation?

A Electrocardiography
B Chest X-ray
C Rheography of the pulmonary artery
D Doppler echocardiography
E Ultrasound of the liver
10

A 10-year-old boy, who was outdoors in windy and cold weather, developed moderate pain and tingling in his ?ngers and toes. When he had returned home, his parents noticed that the tips of his ?ngers and toes were white and their sensitivity was lost. The affected areas are warming up, the ?ngers are tingling and in pain. Skin pallor changed into redness, tingling stopped, slight itching and swelling of the ?ngers appeared. Determine the frostbite degree in this child:

A Perniosis
B Frostbite of the II degree
C Frostbite of the III degree
D Frostbite of the I degree
E Frostbite of the IV degree
11

A 25-year-old woman complains of fatigue, dizziness, hemorrhagic rashes on the skin. She has been presenting with these signs for a month. Blood test: erythrocytes - 1.0 × 10¹²/L, Hb- 37 g/L, colour index - 1.1, leukocytes 1.2 × 10⁹/L, platelets - 42 × 10⁹/L. What analysis would be the most advisable for diagnosismaking in this case?

A Sternal puncture (bone marrow biopsy)
B Liver biopsy
C Coagulation studies
D Splenic biopsy
E US of the gastrointestinal tract
12

A 12-year-old boy with hypertrophic cardiomyopathy complains of dyspnea caused by the slightest physical exertion. Echocardiography detected asymmetrical left ventricular hypertrophy, signs of pulmonary hypertension, and left ventricular dilatation, its ejection fraction is 59%. These developments are indicative of:

A Heart failure with preserved ejection fraction
B Symptomatic arterial hypertension
C Essential hypertension
D Primary pulmonary hypertension
E Heart failure with reduced ejection fraction
13

A 35-year-old man complains of rapidly incresing fatigue, palpitations, ”visual snow”, dizziness. He has a history of peptic ulcer of the stomach. Objectively the skin is pale. Vesicular respiration is observed in the lungs. Systolic murmur is detected over the cardiac apex, heart rate is 100/min., BP is 100/70 mm Hg. The epigastrium is slightly tender on palpation. Blood test: erythrocytes - 3.2 × 10¹²/L, Нb- 100 g/L, color index - 0.94. What type of anemia is the most likely present in this case?

A Hypoplastic anemia
B Hemolytic anemia
C Sideroblastic anemia
D Posthemorrhagic anemia
E Iron-de?ciency anemia
14

A 35-year-old patient has been suffering from an illness for 3 days. 5 days ago he returned from a trip to Africa. The onset of disease was accompanied by fever up to 40°C, chills, acute headache, myalgia. In the axillary region the lymph node enlarged up to 3x6 cm can be palpated. The lymph node is dense, intensely painful, slightly mobile, without clear margins; the skin over the node is hyperemic and tight. Tachycardia is present. Make the preliminary diagnosis:

A Tu l a r e m i a
B Lymphadenitis
C Sepsis
D Anthrax
E Plague
15

Caries morbidity rate is 89% among residents of a community. It is determined that ?uorine content in water is 0.1 mg/L. What preventive measures should be taken?

A Introduce more vegetables to the diet
B Tooth brushing
C Sealant application
D Fluorine inhalations
E Water ?uorination
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16

During appointment with the doctor a man complains of painful itching rashes that appeared on his skin under the beard and moustache one year ago, with frequent exacerbations occurring throughout the year. Objectively the skin of the facial hair growth areas is bluish-purple, thickened, with pustules, erosions, and scabs covering its moist surface. The ?stulous tracts are surrounded by the area of loose pink-red granulation and discharge pus. The skin resembles mulberry in appearance. Make the diagnosis:

A Deep trichophytosis
B Acne rosacea
C Lupus erythematosus
D Sycosis
E Tuberculous lupus
17

A 60-year-old man presents with ischemic heart disease and heart failure of the IV class according to NYHA (New York Heart Association) that manifests as dyspnea at rest. There are moist crackles in the patient's lungs. Liver +4 cm, lower limbs are swollen. Ejection fraction is 25%. What sign is the most indicative when determining functional class of heart failure according to NYHA?

A Degree of dyspnea
B Extent of liver enlargement
C Moist crackles in the lungs
D Decrease of ejection fraction
E Swollen lower limbs
18

A 39-year-old man, a battery attendant, suddenly developed weakness, loss of appetite, nonlocalized colicky abdominal pains, and nausea. Objectively his skin is gray; there is pink-gray stripe on his gums; the stomach is soft and sharply painful. Blood test detected erythrocytes with basophilic stippling and anemia. The patient has a history of peptic ulcer disease of the stomach. There is tendency to constipation. What is the most likely provisional diagnosis?

A Saturnism (lead poisosning)
B Chronic alcoholism
C Perforation of gastric ulcer
D Acute appendicitis
E Acute cholecystitis
19

A 9-month-old infant presents with delayed tooth eruption and fontanel closure, weakness, and excessive sweating. What type of hypovitaminosis is the most likely in this child?

A Hypovitaminosis D
B Hypovitaminosis C
C Hypovitaminosis A
D Hypovitaminosis B₆
E Hypovitaminosis B₁
20

A 10-year-old girl exhibits high level of physical development (? +3σ), her body length increased by 10 cm within a year (which is double the norm for her age group), the number of permanent teeth corresponds with the age norm (20), the development of her secondary sex characteristics is three years ahead of her age (Ма, Р, Ах, Menarche). Development rate ahead of her biological age can occur due to:

A Sports training
B Acceleration
C Certain components of her diet
D De?cient hygienic education
E Endocrine disorders
21

An infant has been born at the 41st week of gestation. The pregnancy was complicated with severe gestosis of the second semester. The weight of the baby is 2400 g, the height is 50 cm. Objectively: the skin is ?abby, the layer of subcutaneous fat is thin, hypomyotonia, neonatal re?exes are weak. The internal organs are without pathologic changes. This newborn can be assessed as a:

A Full-term infant with normal body weight
B Immature infant
C Postmature infant
D Premature infant
E Full-term infant with intrauterine growth retardation
22

A patient suffering from in?ltrative pulmonary tuberculosis was prescribed streptomycin, rifampicin, isoniazid, pyrazinamide, vitamin C. One month after the beginning of the treatment the patient started complaining of reduced hearing and tinnitus. What drug has such a side effect?

A Streptomycin
B Isoniazid
C Pyrazinamide
D Vitamin C
E Rifampicin
23

The doctor has an appointment with a patient, who 2 days ago developed severe chest pain on the left, general weakness, high temperature, and headache. Objectively along the 4th and 5th intercostal nerves on the left the skin is hyperemic and there are tight clusters of small vesicles ?lled with clear serous content. What is the most likely diagnosis?

A Dermatitis herpetiformis (Duhring's disease)
B Herpes zoster
C Streptococcal impetigo
D Pemphigus
E Herpes simplex
24

A worker of a blowing shop complains of headache, irritability, sight impairment - he sees everything as if through a ”net”. Objectively: hyperemic sclera, thickened cornea, decreased opacity of pupils, visual acuity is 0.8 in the left eye, 0.7 in the right eye. The worker uses no means of personal protection. What diagnosis is the most likely?

A Keratitis
B Progressive myopia
C Blepharospasm
D Conjunctivitis
E Cataract
25

For a week a 42-year-old patient has been suffering from fever attacks followed by high temperature, which occur every 48 hours. Body temperature raises up to 40°C and decreases in 3-4 hours with excessive sweating. The patient presents with loss of appetite and general fatigue. The skin is pale and sallow. The liver and spleen are enlarged and dense on palpation. What method of diagnosis veri?cation would be most ef?cient?

A Immune-enzyme assay
B Microscopy of blood smear and thick blood ?lm
C Bacteriological analysis
D Complete blood count
E Microscopy of hanging blood drop
26

A 16-year-old adolescent living in a rural area has been bitten in the shin by a stray dog. The wound is super?cial. Regular vaccination against tetanus was received 3 months ago. What treatment tactics would be the most advisable in this case?

A Antitetanus serum
B Antirabies vaccination
C Antitetanus immunoglobulin
D Tetanus toxoid adsorbed
E Antirabies immunoglobulin
27

A 26-year-old woman is suspected to suffer from systemic lupus erythematosus with systemic lesions of skin, vessels, joints, serous tunics, and heart tissue that developed after photosensitization. The following is detected in blood analysis: LE cells, antibodies to native ds-DNA, isolated anti-centromere antibodies, rheumatoid factor is 1:100, Wassermann reaction is positive, circulating immune complex is 120 units. What immunological indicators are considered to be speci?c to this disease?

A Immunoglobulin A
B Increased circulating immune complex
C Anti-centromere antibodies
D Rheumatoid factor
E ds-DNA antibodies
28

A group of 5 had been resting in a forest, they were drinking alcohol and eating canned mushrooms and cured ?sh. The next day two of them were hospitalized with disturbed vision, swallowing and respiration; the third one presented with acute general weakness and dry mouth. The remaining two were healthy. A tick was detected on the skin of one of the healthy group members. What is the most likely diagnosis?

A Botulism
B Tick-borne encephalitis
C Mushroom poisoning
D Lyme borreliosis
E Alcohol poisoning
29

A 23-year-old man complains of facial edema, headache, dizziness, low urinary output, urine discoloration (dark red). These complaints arose after the patient had had a case of acute tonsillitis. On examination there are facial edema, the skin is pale, temperature is 37.4°C; heart rate is 86/min., blood pressure is 170/110 mm Hg. Heart sounds are muf?ed, the II heart sound is accentuated over the aorta. What etiological factor is the most likely in this case?

A Beta-hemolytic streptococcus
B Staphylococcus saprophyticus
C Streptococcus pyogenes
D Streptococcus viridans
E Staphylococcus aureus
30

During examination a 4-month-old child with meningococcemia presents with acrocyanosis, cold extremities, tachypnea, and thready pulse, blood pressure of 30/0 mm Hg, anuria, and sopor. What clinical syndrome is it?

A Acute renal failure
B Neurotoxicosis
C Exicosis
D Septic shock
E Encephalic syndrome
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31

The pregnancy is full term. The body weight of the parturient woman is 62 kg. Fetus is in a longitudinal lie, the head is engaged to the pelvic inlet. Belly circumference is 100 cm. Uterine fundus height is 35 cm. What body weight of the fetus can be expected?

A 3.5 kg
B 2.5 kg
C 4.5 kg
D 4kg
E 3kg
32

An 18-year-old young man complains of pain in his knee and elbow joints and body temperature up to 39.5°C. One week and a half earlier developed sore throat. On examination his body temperature is 38.5°C. Swelling of the knee and elbow joints is observed. Pulse is 106/min., rhythmic. Blood pressure is 90/60 mm Hg. Cardiac borders are unchanged, heart sounds are weakened, at the cardiac apex there is soft systolic murmur. What factor would be the most indicative of the likely disease etiology?

A Seromucoid
B Creatine kinase
C C-reactive protein
D Rheumatoid factor
E Anti-streptolysin O
33

A 20-year-old patient complains of severe headache, double vision, weakness, fever, irritability. Objectively: body temperature is 38.1°C, the patient is reluctant to contact, sensitive to stimuli. There are ptosis of the left eyelid, exotropia, anisocoria S>D, pronounced meningeal syndrome. On lumbar puncture the cerebrospinal ?uid ?owed out under a pressure of 300 mm Hg, the ?uid is clear, slightly opalescent. 24 hours later there appeared ?brin ?lm. Protein - 1.4 g/L, lymphocytes - 600/3 per mm3, sugar - 0.3 mmol/L. What is the provisional diagnosis?

A Mumps meningitis
B Tuberculous meningitis
C Syphilitic meningitis
D Meningococcal meningitis
E Lymphocytic (Armstrong's) meningitis
34

A 32-year-old woman complains of increasing spastic pains in her lower abdomen that occur after emotional stress. Bowel movements are intermittent: 2-3 defecations after waking in the morning alternate with constipations that last for 1-2 days. Objectively body mass is retained, palpation of the sigmoid colon is moderately painful. Hb- 130 g/L, leukocytes 5.2 g/L, ESR- 9 mm/hour. Rectoromanoscopy is painful due to spastic condition of the intestine, intestinal mucosa is without changes. Intestinal lumen contains large amounts of mucus. What is the most likely diagnosis in this case?

A Crohn's disease (regional enteritis)
B Malabsorption syndrome
C Acute mesenteric ischemia
D Nonspeci?c ulcerative colitis
E Irritable bowel syndrome
35

The inpatient surgery unit has introduced the method of laparoscopic cholecystectomy into its practice. As the result the average duration of postoperative care provided to the patients could be reduced to 3.4±0.8 days compared to 7.3±1.1 days that were required after non-laparoscopic cholecystectomy. What method of medical statistics can con?rm the statistical signi?cance of the difference between these two estimates?

A Calculation of average values (measures of central tendency)
B Calculation of correlation coef?cient
C Calculation of Student's con?dence interval
D Calculation of standardized ratio
E Calculation of relative values
36

A 37-year-old worker during a ?re ended up in the area of high CO concentration. He was delivered to a hospital in unconscious state. Objectively: the skin of his face and hands is crimson. Respiration rate is 20/min. ECG: alterations speci?c for hypoxic myocardium. Hourly diuresis is 40 ml. Blood test: erythrocytes 4.5×10¹²/L, Нb- 136 g/L, color index - 0.9, ESR3 mm/hour, carboxyhemoglobin - 5%. What criterion allows determining the severity of the patient's condition?

A Extent of trophic disorders
B Respiratory disorders
C ECG results
D Development of chronic renal failure
E Carboxyhemoglobin concentration
37

The right arm of a newborn is stretched along the torso with all its joints extended; the shoulder is rotated inwards, while the forearm is pronated, the hand is in the position of palmar ?exion. Spontaneous movements are absent in the shoulder and elbow joints, passive movements are painless. What is the most likely diagnosis?

A Poliomyelitis
B Dejerine-Klumpke palsy, inferior distal type
C Duchenne-Erb palsy, superior proximal type
D Osteomyelitis of the right humerus
E Total obstetric palsy
38

In April during the medical examination of various population groups, 27% of individuals presented with low working ability and rapid fatigability. The following symptoms were observed in the affected individuals: swollen friable gingiva that bleeds when pressed, hyperkeratosis follicularis not accompanied by skin dryness. These symptoms most likely result from the following pathology:

A Polyhypovitaminosis
B Parodontosis
C ю1-hypovitaminosis
D C-hypovitaminosis
E A-hypovitaminosis
39

A 1-year-old child with a case of URTI suddenly developed noisy respirations with dif?cult inspiration, intercostal retractions, and barking cough on the 2nd night after the disease onset. What is the most likely diagnosis?

A Acute pulmonary in?ammation
B Acute bronchitis
C Stenosing laryngotracheobronchitis
D Acute bronchiolitis
E Bronchial asthma
40

A 46-year-old woman complains of severe pain attacks in the right lumbar area, which irradiate to the lower abdomen, and nausea. This kind of pain attacks has never been detected in the patient before. Plain abdominal X-ray reveals no pathologic shadows. Ultrasound detects a hyperechogenic mass 1.5 cm in diameter, which re?ects sound wave, in the enlarged right renal pelvis. What diagnosis is the most likely?

A Renal calculus
B Renal cyst
C Malignant renal tumor
D Benign renal tumor
E Renal tuberculosis
41

A 60-year-old woman complains of unbearable pain in her right subcostal area. She has a history of acute pancreatitis. Temperature is 38.2°C. Objectively her sclera are icteric. There are no signs of peritoneal irritation. Ortner's and Gubergrits' symptoms are positive. Urine diastase is 320 U/L. What is the most likely diagnosis?

A Exacerbation of chronic pancreatitis
B Acute cholecystitis
C Chronic cholecystitis
D Acute cholangitis
E Pancreatic cancer
42

A 64-year-old man complains of cough with expectoration consisting of blood-streaked mucus, dyspnea, low grade fever and general fatigue. He has been presenting with these symptoms for 3 months. He has been smoking since early adolescence. Objectively to is 37.4°C, respirations are 26/min., pulse is 82/min., rhythmic, blood pressure is 130/85 mm Hg. The right side of the thorax lags behind in the respiratory process, dull percussion sound and acute decrease of breathing activity are observed there. X-ray shows homogeneous shadow of the lung ?eldontherightwithmediastinum displacement towards the affected side. What is the most likely diagnosis?

A Pulmonary tuberculosis
B Central lung cancer
C Multiple bronchiectasis
D Pleuropneumonia
E Exudative pleuritis
43

For 4 days a 35-year-old man has been treated in the resuscitation unit for acute renal failure caused by compartment syndrome. The patient is disoriented. ECG shows high T waves and right ventricular extrasystoles. His central venous pressure is 159 mmH2O; for the last 3 hours auscultation has been detecting isolated moist crackles in the lungs. Respirations are 32/min. Blood test: residual nitrogen 62 mmol/L, K+ - 7.1 mmol/L, Cl? - 78 mmol/L, Na+ - 120 mmol/L, Ht- 0.32 L/L, Hb- 100 g/L, blood creatinine - 0.9 mmol/L. In this case the most advisable would be to perform:

A Plasma?ltration
B Ultra?ltration
C Hemodialysis
D Hemosorption
E Plasmasorption
44

A 55-year-old woman, a cook, complains of pain in her right knee joint that has been troubling her for a month and intensi?es in the evening. Objectively she is overweight, the knee joint is swollen, creaks during movement, palpation reveals localized pain. The 1st metatarsophalangeal articulation is deformed on the both feet. No changes in blood and urine are detected. What should be visible on the patient's X-ray?

A Joint space narrowing, round bone defects
B Joint space narrowing, multiple usurations, subluxations
C Osteoporosis, joint space narrowing, singular usurations
D Epiphyseal erosions, bony ankylosis
E Joint space narrowing, marginal osteophytes
45

A 52-year-old woman has been suffering for 2 years from dull, occasionally exacerbating pain in her right subcostal area, occurring after eating high-fat foods, bitter taste in her mouth in the morning, constipations, and ?atulence. Objectively she has excess weight, her body temperature is 36.9°C; there is a coating on the root of her tongue; the abdomen is moderately distended and painful in the area of gallbladder projection. What examination would be the most helpful for diagnosis-making?

A Ultrasound
B Duodenoscopy
C Liver scanning
D Cholecystography
E Duodenal intubation
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46

A 57-year-old woman complains of weakness, dyspnea, loss of appetite, and liquid feces. She has been suffering from this condition for 2 years. Objectively she presents with pale skin, subicteric sclera, and brightred ?ssured tongue. Lymph nodes are not enlarged. Pulse - 100/min. BP- 105/70 mm Hg. Liver +3 cm, the spleen cannot be palpated. Blood test: erythrocytes - 1.2 × 10¹²/L, Нb- 56 g/L, color index - 1.4, macrocytes, leukocytes - 2, 5 × 10⁹/L, eosinophils - 1%, juvenile - 1%, metamyelocytes - 1%, band neutrophils - 8%, segmented neutrophils - 47%, lymphocytes 38%, monocytes - 4%, reticulocytes - 0.1%, platelets - 100 × 10⁹/L, ESR- 30 mm/hour, indirect bilirubin - 26 mmol/L. What changes can be expected in the bone marrow puncture material?

A Prevalence of megaloblasts
B Prevalence of lymphoid tissue
C Increased number of sideroblasts
D Presence of blast cells
E Erythroid hyperplasia
47

A 45-year-old woman complains of paroxysmal intolerable facial pain on the left with attacks that last for 1-2 minutes. Attacks are provoked by chewing. The disease onset was two month ago after overexposure to cold. Objectively: pain at the exit points of the trigeminal nerve on the left. Touching near the wing of nose on the left induces new pain attack with tonic spasm of the facial muscles. What is the most likely diagnosis among those listed?

A Maxillary sinusitis
B Glossopharyngeal neuralgia
C Facial migraine
D Trigeminal neuralgia
E Temporomandibular joint arthritis
48

A 10-year-old boy with symptoms of arthritis and myocarditis was delivered into a hospital. Based on clinical examination the preliminary diagnosis of juvenile rheumatoid arthritis was made. What symptom is the most contributive for the diagnostics of this disease?

A Reduced mobility of the joints in the morning
B Affection of the large joints
C Regional hyperemia of the joints
D Enlarged heart
E Increased heart rate
49

A 25-year-old patient was delivered to an infectious diseases unit on the 3rd day of illness with complaints of headache, pain in lumbar spine and gastrocnemius muscles, high fever, chill. Objectively: condition of moderate severity. Scleras are icteric. Pharynx is hyperemic. Tongue is dry with dry brown coating. Abdomen is distended. Liver is enlarged by 2 cm. Spleen is not enlarged. Palpation of muscles, especially gastrocnemius muscles, is painful. Urine is dark in colour. Stool is normal in colour. The most likely diagnosis is:

A Leptospirosis
B Malaria
C Yersiniosis
D Infectious mononucleosis
E Viral hepatitis type A
50

A 28-year-old woman complains of skin hemorrhages after minor traumas and spontaneous appearance of hemorrhages on the front of her torso and extremities. On examination: the skin is variegated (old and new hemorrhages), bleeding gums. Blood platelets - 20 × 10⁹/L; in the bone marrow there is increased number of megakaryocytes and no platelet production. Treatment with steroid hormones was effective. What is the likely diagnosis?

A Rendu-Osler-Weber disease (Hereditary hemorrhagic telangiectasia)
B Idiopathic thrombocytopenic purpura
C Hemophilia
D Disseminated intravascular coagulation
E Acute vascular purpura
51

A 7-year-old boy has been an inpatient for 1.5 months. He had been delivered to the hospital with complaints of edemas all over his body, low urine output, and headache. Clinical urinalysis: proteins - 7.1 g/L, leukocytes - 1-2 in the vision ?eld, erythrocytes - 3-4 in the vision ?eld. During the course of treatment the edemas gradually dissipated, headache abated, diuresis normalized. Daily urine proteins - 3 g/L. Biochemical blood test: total protein - 43.2 g/L, urea - 5.2 mmol/L, cholesterol - 9.2 mmol/L. What glomerulonephritis syndrome is the most likely to be present in the patient?

A Nephrotic
B Nephritic
C Isolated urinary
D Hematuric
E Mixed
52

The mother of a 3-month-old child came to a family doctor with complaints of her child being physically underdeveloped and suffering from cough attacks and dyspnea. Anamnesis: the child is the result of the second full-term pregnancy with the risk of miscarriage (the ?rst child died of pulmonary pathology at the age of 4 months, according to the mother). Body mass at birth is 2500 g. Cough attacks were observed from the ?rst days of life, twice the child was treated for bronchitis. Considering the severity of the child's condition the doctor made the referral for hospitalization. What diagnosis was most likely stated in the referral?

A Mucoviscidosis (Cystic ?brosis)
B Pertussis
C Acute obstructive pneumonia
D Recurrent obstructive bronchitis
E Acute obstructive bronchitis
53

A 10-year-old girl complains of stomachache that appears and intensi?es after she eats rough or spicy food, sour eructation, heartburn, frequent constipations, headaches, irritability. She has been presenting with these signs for 12 months. Her meals are irregular and consist of dry food. Objectively her diet is suf?cient in calories. The tongue is moist with white coating near the root. The abdomen is soft and painful in the epigastrium. What method would be optimal for diagnosis-making in this case?

A Fractional gastric analysis (Fractional test meals)
B Intragastric pH-metry
C Phase-contrast X-ray imaging
D Esophagogastroduodenoscopy
E Biochemical blood test
54

A 23-year-old patient had taken 1 g of aspirin to treat acute respiratory infection. After that he developed an asthmatic ?t with labored expiration that was arrested by introduction of aminophylline. The patient's medical history is not burdened with allergies. The patient has undergone two surgeries for nasal polyposis in the past. What diagnosis is most likely?

A Infectious allergic bronchial asthma
B Atopic bronchial asthma
C Symptomatic bronchospasm
D Exercise-induced asthma
E Aspirin-induced asthma
55

A 50-year-old patient was delivered to a hospital with complaints of blood traces in urine. Urination is painless and undisturbed. Macrohematuria had been observed for 3 days. Objectively: kidneys cannot be palpated, suprapubic area is without alterations, external genitalia are non-pathologic. On rectal investigation: prostate is not enlarged, painless, has normal structure. Cystoscopy revealed no alterations. What is the most likely diagnosis?

A Dystopic kidney
B Bladder tuberculosis
C Necrotic papillitis
D Varicocele
E Renal carcinoma
56

A 36-year-old man has been complaining of marked weakness, low appetite, and nausea for the last year, year and a half. Within the last year he has lost 10 kg of body mass. The skin is darkened, especially on his face, neck, and arms. Skin folds and nipples are hyperpigmented, there are pigment spots on the patient's inner thighs. Pulse is 60/min., blood pressure is 80/50 mm Hg. What is the provisional diagnosis?

A Hemochromatosis
B Diabetes mellitus
C Adrenal insuf?ciency
D Cholestatic hepatitis
E Chronic gastritis
57

A 5-year-old child that contacts with viral hepatitis in the kindergarten presents with increased body temperature up to 38°C, weakness, low appetite, single case of vomiting, dull pain in the subcostal area on the right. The child is provisionally diagnosed with viral hepatitis. What examination would be the most informative for diagnosis con?rmation?

A Blood test for bilirubin
B Thymol turbidity test
C Feces analysis for stercobilin
D ALT activity in blood
E Urine analysis for bile pigments
58

A patient with trauma of the lower third of the forearm volar surface caused by a glass shard came to a ?rst-aid center. Objectively: ?exion of the IV and V ?ngers is impaired, sensitivity of the inner dorsal and palmar surfaces of the hand and IV ?nger is decreased. What nerve is damaged?

A Ulnar
B Axillary
C Musculocutaneous
D Median
E Radial
59

A man diagnosed with closed-angle glaucoma, grade IIa, of the right eye is registered for regular medical check-ups. In the evening an acute glaucoma attack occurred in his right eye; an ambulance was called. What emergency aid would be optimal in this case?

A Pilocarpine, Diacarb (Acetazolamide), lytic mixture
B Sulfacetamide sodium eye drops
C Dexamethasone eye drops
D Atropine eye drops
E Antibiotic eye drops, broad-spectrum
60

A 58-year-old patient complains of pain in the lower left extremity, which aggravates during walking, and sensation of cold and numbness in the both feet. The patient has been suffering from this condition for 6 years. Objectively: the skin is pale and dry, with hyperkeratosis. On the left shin hair is scarce. Pulse cannot be detected over the pedal and popliteal arteries and is weakened over the femoral artery. On the right limb pulsation of the popliteal artery is retained. What is the most likely diagnosis?

A Femoral artery thrombosis
B Obliterating endarteritis
C Raynaud's disease
D Buerger's disease (thromboangiitis obliterans)
E Atherosclerosis obliterans of the lower extremities
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61

A 22-year-old woman, gravida 1, para 0 arrived with complaints of sharply painful contractions that occur every 4-5 minutes and last for 25-30 seconds. Amniotic ?uid did not burst. The fetus is in transverse lie, fetal heartbeats are not affected. Contraction ring is acutely painful, located obliquely at the umbilicus. What is the most likely diagnosis?

A Discoordinated labor
B Impending uterine rupture
C Uterine rupture
D Excessive uterine activity during labor
E Uterine tetany
62

During regular check-up the doctor examines a young woman, a student, with height of 162 cm and weight of 59 kg. She complains that in the evening she becomes unable to see clearly the objects around her. Objectively her skin is dry, presents with hyperkeratosis. Her daily ration has the following vitamin content: vitamin A - 0.5 mg, vitamin B₁ - 2.0 mg, vitamin B₂ - 2.5 mg, vitamin B₆ - 2 mg, vitamin C -70 mg. Make the diagnosis:

A B₆-hypovitaminosis
B A-hypovitaminosis
C B₁-hypovitaminosis
D C-hypovitaminosis
E B₂-hypovitaminosis
63

An infant is 2.5 months old. The onset of the disease was gradual, the child had normal body temperature but presented with slight cough. Within a week the cough intensi?ed, especially at night; on the 12th day the child developed cough ?ts occurring up to 20 times per day and followed by vomiting. There was one instance of respiratory arrest. Make the diagnosis:

A Pertussis
B Respiratory syncytial infection
C Adenovirus infection
D Congenital stridor
E Parain?uenza
64

A man works in casting of nonferrous metals and alloys for 12 years. In the air of working area there was registered high content of heavy metals, carbon monoxide, and nitrogen. During periodic health examination the patient presents with asthenovegetative syndrome, sharp pains in the stomach, constipations, pain in the hepatic area. In urine: aminolevulinic acid and coproporphyrin are detected. In blood: reticulocytosis, low hemoglobin level. Such intoxication is caused by:

A Carbon monoxide
B Lead and lead salts
C Zinc
D Nitric oxide
E Tin
65

Due to introduction of a new treatment method, average duration of therapy in the experimental group was 12.3±0.2 days compared to 15.4±0.4 days in the control group that was treated by the old method. What calculations should be made to estimate the statistical signi?cance of the difference in the results?

A Matching factor (chi-squared test)
B Kolmogorov-Smirnov test
C Sign test (Z-test)
D T-test (Student's t-distribution)
E Wilcoxon T-test
66

Establishments participating in medical examinations include: medical and preventive treatment facilities, hygiene and preventive treatment facilities, sociomedical expert committees, Ministry of Defence medical committees, Ministry of Domestic Affairs medical committees, forensic medicine agency, etc. Specify what service deals with sociomedical assessment of temporary disability:

A Ministry of Domestic Affairs medical committees
B Ministry of Defence medical committees
C Medical and preventive treatment facilities
D Sociomedical expert committees
E Hygiene and preventive treatment facilities
67

A 14-year-old boy presents with moderate bronchial asthma in its exacerbation period. What drug should be prescribed to stop an acute attack of expiratory dyspnea?

A Strophanthine (cardiac glycosides)
B Lasolvan (Ambroxol)
C Cromolyn sodium (Cromoglicic acid)
D Dexamethasone
E Salbutamol
68

A newborn with gestational age of 31 weeks presents with hypotonia and depressed consciousness. Hematocrit is 35%, general cerebrospinal ?uid analysis shows increased content of erythrocytes and protein, and low glucose. These data correspond with the clinical presentation of:

A Meningitis
B Prenatal infection
C Intracranial hemorrhage
D Sepsis
E Anemia
69

A 16-year-old girl has primary amenorrhea, no pubic hair growth, normally developed mammary glands; her genotype is 46 ХУ; uterus and vagina are absent. What is your diagnosis?

A Cushing syndrome
B Sheehan syndrome
C Cushing disease
D Testicular feminization syndrome
E Mayer-Rokitansky-Kuster-Hauser syndrome
70

6 hours ago the waters of a 30-year-old gravida 1, para 0, burst; her preliminary period was pathologic and lasted for over 2 days; the term of pregnancy is 39 weeks. No labor activity is observed. Fetal head presents above the pelvic inlet. Fetal heartbeats are 142/min., clear and rhytmic. On vaginal examination the uterine cervix is not dilated. What further tactics should the doctor choose?

A Perform cesarean section
B Stimulate the labor with oxytocin
C Prolong the pregnancy, while providing antibacterial treatment
D Induce cervical dilation with prostaglandins
E Wait for the onset of spontaneous labor
71

Mother of an 8-year-old girl complains that the child is too short and has excessive body weight. Objectively: obesity with fat deposits on the torso and face (round moon-like face), acne, striae on the thighs and lower abdomen, hirsutism. What hormone can cause such symptoms, when in excess?

A Thyroxin
B Insulin
C Testosterone
D Cortisol
E Glucagon
72

A 9-year-old girl complains of fever up to 38.5°C, headache, inertness, weakness, loss of appetite, stomachache, and frequent painful urination. Provisional diagnosis of acute pyelonephritis is made. Clinical urine analysis: speci?c gravity - 1016, no protein, leukocytes - 10-15 in the vision ?eld. What investigation method can verify the diagnosis of urinary tract infection?

A Zymnytsky test (density measurement of daily diuresis)
B Bacteriological inoculation of urine
C Rehberg test (creatinine clearance test)
D Complete blood count
E Clinical urine analyses, dynamic testing
73

A newborn has Apgar score of 9. When should the infant be put to the breast?

A On the 2nd day
B After 12 hours
C In the delivery room
D On the 3rd day
E After 2 hours
74

During assessment of work conditions at the factory manufacturing mercury thermometers, the content of mercury vapors in the air of the working area is revealed to exceed the maximum concentration limit. Specify the main pathway of human body exposure to mercury:

A Intact skin
B Respiratory organs
C Gastrointestinal tract
D Mucous tunics
E Damaged skin
75

In the process of hiring, a prospective employee has undergone preventive medical examination and was declared ?ttoworkin this manufacturing environment. What type of preventive medical examination was it?

A Periodical
B Comprehensive
C Speci?c
D Scheduled
E Preliminary
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76

A 47-year-old woman came to the admission room with complaints of general weakness, dizziness, vomiting with blood clots. Condition onset was 3 hours ago. The patient has no preceding illnesses. Blood pressure is 90/60 mm Hg, pulse is 106/min., of poor volume. The abdomen is soft, with mild tenderness in the epigastrium. Blood test: erythrocytes 2.1×10¹²/L, Нb- 70 g/L, hematocrit - 28%. What tactics should the doctor on duty choose?

A Give spasmolytics
B Consult the surgeon
C Refer the patient to the family doctor
D Perform gastric lavage
E Make an appointment for colonoscopy
77

A 23-year-old woman came the the gynecologist with complaints of blood smears from her genital tracts that have been observed for a long time. Her menstruation has been delayed for 8 weeks. Examination shows the uterine body to be enlarged up to 14 weeks of pregnancy. US detected a vesicular mole. What tactics should the doctor choose?

A Curettage of the uterine cavity
B Uterectomy
C Hormonal treatment
D Hemostatic treatment
E Supravaginal uterine amputation
78

A 52-year-old patient complains of pain in the right part of her chest, dyspnea, cough with large amounts of foamy sputum emitting foul smell and resembling ”meat slops”. Objectively: the patient's condition is grave, cyanosis is observed, breathing rate is 31/min., percussion sound above the right lung is shortened, auscultation revealed various moist rales (crackles). What is the most likely diagnosis?

A Lung abscess
B Empyema of pleura
C Chronic pneumonia
D Multiple bronchiectasis
E Lung gangrene
79

A man complains of sore throat on the left, pain in his left ear, to up to 39°C, and nasal sound of his voice. Disease onset was 5 days ago. Marked trismus and increased salivation are observed. The head tilts to the left shoulder. Left side of the soft palate presents with swelling, hyperemia, and in?ltration. Retromandibular lymph nodes on the left are acutely painful on palpation. Otoscopy results are normal. Make the diagnosis:

A Retropharyngeal abscess
B Cervical phlegmon on the left
C Left-sided peritonsillar abscess
D Peritonsillitis on the left
E Parapharyngeal phlegmon
80

A patient has the second and third degree burns of the 15% of the body surface. On the 20th day after the trauma the patient presents with sharp increase of body temperature, general weakness, rapid vesicular respiration; facial features are sharpened, BP is 90/50 mm Hg, heart rate is 112/min. What complication is it?

A Pneumonia
B Anaerobic infection
C Purulent bronchitis
D Sepsis
E Acute intoxication
81

A patient in the state of clinical death is being resuscitated through mouth-to-mouth arti?cial pulmonary ventilation and external cardiac massage. A doctor noticed that air does not ?ow into the patient's airways and his head and torso are positioned at the same level. Why is arti?cial respiration ineffective in the given case?

A Tongue retraction
B The patient's mouth is too small
C Probe is absent from the stomach
D External cardiac massage
E Low breathing volume
82

An employee has been sick for 4 months, further treatment is necessary, the patient is unable to work. Who is authorized to provide further disability examination of this patient?

A Sociomedical expert committee
B Deputy chief responsible for disability examination
C Chief physician of a medical facility
D Medical consultative board
E Physician in charge and the head of the department
83

A population of a small town often presents with registered cases of juvenile cardiomyopathy, atherosclerosis, hypertension, endocrinopathy, chronic dermatitis, and arthralgia - signs of Keshan disease. What is the most likely cause of this pathology?

A Excessive iron in the environment
B Excessive zinc in the environment
C Strontium de?ciency in the environment
D Excessive manganese in the environment
E Selenium de?ciency in the environment
84

In 2 hours after a traf?c accident a 28-yearold man in grave condition was delivered to a hospital. The patient complains of abdominal pain. He received a blow to the abdomen with the steering wheel. Objective examination revealed the following: the abdomen does not participate in respiration, is tense and acutely painful on palpation; abdominal guarding is present, peritoneal irritation signs are positive, hepatic dullness is absent. BP is 90/60 mm Hg, heart rate is 120/min. What further treatment tactics should be chosen?

A Cold to the abdomen
B Laparoscopy
C Abdominal X-ray
D Laparotomy
E Laparocentesis
85

A 48-year-old woman was arrived to the surgical unit with wounds in her thigh. On examination the wound surface has dirty-gray coating with unpleasant sweet smell. Wound content resembles raspberry jelly. Skin tissues around the wound are glossy and turgid. Palpation reveals moderate crepitation in the tissues. What micro?ora is the most likely to cause such in?ammation?

A Staphylococci
B Blue pus bacillus
C Anaerobic non-clostridial
D Anaerobic clostridial
E Streptococci
86

The gynecology unit received a patient with uterine bleeding that started 6 hours after induced abortion at the term of 11-12 weeks. Objectively the skin is pale, pulse is 100/min., blood pressure is 100/70 mm Hg. On vaginal examination the uterus is painless, its enlargement corresponds to the 10th week of pregnancy; uterine cervix is dilated enough to let in one ?nger, there are fragments of the fertilized ovum. What actions should be taken next:

A Urgent repeated curettage of the uterine cavity
B Treatment for acute anemia
C Prescribe rest and continue to monitor the patient's condition
D Uterotonic drugs
E Antibacterial agents
87

A woman came to the general practitioner with complaints of fatigability, signi?cant weight loss, weakness, and loss of appetite. She has been presenting with amenorrhea for the last 8 month. One year ago she gave birth to a live full-term child. Blood loss during delivery was 2 liters. The woman received blood transfusion and blood components. What is the most likely diagnosis?

A Stein-Leventhal syndrome (polycystic ovary)
B Sheehan's syndrome (postpartum hypopituitarism)
C Homologous blood syndrome
D Somatoform autonomic dysfunction
E Turner's syndrome
88

To assess the effectiveness of medical technologies and determine the power and direction of their effect on the public health indicators, the research was conducted to study the immunization rate of children and measles incidence rate by district. What method of statistical analysis should be applied in this case?

A Calculation of correlation coef?cient
B Calculation of morbidity index among the nonvaccinated
C Calculation of standardized ratio
D Calculation of coef?cient of agreement
E Calculation of statistical signi?cance of the difference between two estimates
89

A 22-year-old woman complains of itching and profuse discharge from her genital tracts. The condition developed 10 days ago after a sexual contact. Bacterioscopy of a discharge sample detected trichomonads. What drug should be prescribed for treatment in this case?

A Valcyclovir
B Ampicillin
C Zovirax (Acyclovir)
D Erythromycin
E Metronidazole
90

A 30-year-old patient was hospitalized in an intensive care unit with a diagnosis of multiple bee stings. Skin is pale and covered with cold sweat. Pulse can be palpated only at the carotid arteries and is 110/min.; breathing rate is 24/min., rhytmical, weakened. What drug must be administered immediately?

A Dopamine
B Norepinephrine hydrochloride
C Epinephrine hydrochloride
D Tavegyl (Clemastine)
E Prednisolone
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91

A 46-year-old woman has been hospitalized with open fracture of the left thigh in its middle third. She underwent the surgery - ?xation with extraosseous osteosynthesis plates. On the 4th day after the surgery she developed pain in the wound, body temperature rose over 39°C. What measures should be taken in this case?

A Inject antibiotics into the area surrounding the wound, prescribe spasmolytics and analgesics
B Prescribe broad spectrum antibiotics and hormonal agents
C Administer antibiotics intraosseously and hypothermia locally
D Remove the ?xation, prescribe sulfanilamides
E Undo the sutures, drain the wound, and prescribe antibiotics
92

A woman with blood group B(III) Rh(+) gave birth to a full-term healthy boy. Examination on the 3rd day of the infant's life shows him to have icteric tint to his skin. The child has no problems with suckling, sleep is nondisturbed. The abdomen is soft, the liver protrudes by 2 cm from under the costal margin. Complete blood count: hemoglobin 200 g/L, erythrocytes - 5.5 × 10¹²/L, total bilirubin - 62 mcmol/L, indirect bilirubin - 52 mcmol/L. What condition can be suspected?

A Hemolytic disease of the newborn due to ABO incompatibility
B Hemolytic disease of the newborn due to Rh incompatibility
C Biliary atresia
D Physiologic jaundice
E Congenital hepatitis
93

A 45-year-old man developed constricting retrosternal pain that occurs during walks at the distance of 200 m. Objectively heart rate is 80/min., BP is 160/90 mm Hg. During cardiopulmonary exercise test at 50 W there is a depression of S-T segment by 3 mm below the isoline in V3-V4. What is the provisional diagnosis?

A Exertional angina pectoris, functional class II
B Alcoholic myocardiodystrophy
C Exertional angina pectoris, functional class IV
D Somatoform autonomic dysfunction, hypertension type
E Exertional angina pectoris, functional class III
94

A multigravida on the 38th week of her pregnancy complains of increased BP up to 140/90 mm Hg, edema of the shins for 2 weeks. In the last month she gained 3.5 kg of weight. Urine analysis: protein - 0.033 g/L. Make the diagnosis:

A Severe preeclampsia
B Pregnancy edema
C Moderate preeclampsia
D Mild preeclampsia
E Pregnancy hypertension
95

For the last 15 years a 48-year-old patient has been working at the factory producing synthetic resins. Lately he has been complaining of signi?cant general fatigue, headaches, frequent urination (predominantly during the day), red color of urine. What complication of benzene nitrocompounds poisoning can be suspected?

A Malignant tumor of the urinary bladder
B Acute glomerulonephritis
C Chronic pyelonephritis
D Chronic cystitis
E Chronic prostatitis
96

A 44-year-old patient with postinfarction cardiosclerosis presents with frequent heart rate disorders and lower extremity edema. Objectively: Ps- 95/min., irregular, 1012 extrasystoles per minute. BP- 135/90 mm Hg. The 1st heart sound at the apex is weakened. Pulmonary respiration is rough. The liver is enlarged +2 cm. ECG: irregular sinus rhythm, heart rate - 95/min., frequent polytopic ventricular extrasystoles. What antiarrhythmic drug is advisable in this case for treatment and prevention of extrasystole?

A Quinidine
B Mexiletine
C Novocainamide (Procainamide)
D Lidocaine
E Amiodarone
97

A 60-year-old woman started feeling weakness, vertigo, rapid fatigability during the last year. Recently she has developed dyspnea and paresthesia observed. Objectively: skin and mucous membranes are pale and icteric. Lingual papillae are smoothed out. Liver and spleen are at the edge of costal arch. Blood test: Hb- 70 g/L, erythrocytes - 1.7 × 10¹²/L, blood color index - 1.2, macrocytes. What drug can be prescribed on pathogenetic grounds?

A Iron preparations
B Vitamin B₆
C Vitamin B₁₂
D Vitamin B₁
E Ascorbic acid
98

After excessive consumption of fatty food a 60-year-old woman suddenly developed pain in her right subcostal area, nausea, bile vomiting, sharp bitter taste in her mouth. In 2 days she developed jaundice, her urine darkened. Objectively: sclera and skin are icteric, the abdomen is distended, the liver is enlarged by 3 cm, soft and painful on palpation, Ortner's, Murphy's, Kehr's, Zakharyin's, Mayo-Robson's signs are positive. What diagnostic technique should be used in the ?rst place to con?rm the diagnosis?

A Abdominal X-ray
B Ultrasound of the gallbladder and bile duct
C Laparoscopy
D Fibrogastroduodenoscopy
E Radionuclide scanning of the liver and gallbladder
99

The objective of a statistical research was to ?nd out to what extent the population peruses the available medical services. For this purpose 300 residents of the area were interviewed. Information was collected by means of a special questionnaire. What method of collecting information was used by the researchers?

A Anamnestic (history-taking)
B Doing extracts
C Immediate registration
D Immediate examination
E —
100

A 30-year-old woman complains of increased body weight and problems with physical exertion. Her parents are of increased body weight as well; typical meals in their family are high in fats and carbohydrates. Objectively her blood pressure is 135/80 mm Hg, pulse is 89/min., weight is 87 kg, height is 165 cm. The patient's skin is clear, with even distribution of subcutaneous fat; the thyroid gland is not enlarged; there are no menstrual cycle disturbances. What obesity prevention methods would be the most advisable in this case?

A Intensive training regimen
B Dietary treatment, graduated exercise
C Anorectic drugs
D Gastroplasty or gastrojejunal shunt
E Inhibitors of gastrointestinal lipases
101

A 43-year-old woman complains of pain in the lumbar area, which irradiates to her left leg and aggravates on movement, and sensation of numbness in this leg. Objectively palpation of her shin and thigh is painful, there are painful stretch symptoms of on the left and gastrocnemius cramps. There is no sensory loss or weakening of re?ex responses. Make the diagnosis:

A Left-sided coxitis
B Spinal stroke
C Endarteritis of the lower extremities
D Vertebrogenous lumbar ischialgia on the left
E Vertebrogenous radicular syndrome of L5-S1 on the left
102

A 3-day-old infant with hyperbilirubinemia (428 mcmol/L) developed disturbances manifesting as periodical excitation and convulsions against the background of inertness, hypotension, hypodynamia, and inhibition of unconditioned re?exes, convergent strabismus, rotational nystagmus, and settingsun eye phenomenon. What is the most likely cause of such symptoms?

A Brain tumor
B Hydrocephalus
C Bilirubin encephalopathy
D Craniocerebral injury
E Infantile cerebral paralysis
103

A woman undergoing in-patient treatment for viral hepatitis type B developed headache, nausea, recurrent vomiting, memory lapses, ?apping tremor of her hands, rapid pulse. Sweet smell from the mouth is detected. Body temperature is 37.6°C, heart rate is 89/min. What complication developed in the patient?

A Ischemic stroke
B Meningoencephalitis
C Acute liver failure
D Gastrointestinal hemorrhage
E Hypoglycemic shock
104

A patient with chronic pancreatitis complains of diarrhea occurring up to 5 times per day (no blood traces), loss of body weight, abdominal distention, dryness of skin, loss of hair, thirst, bleeding gums, convulsions. Complete blood count: leukocytes - 5.8 × 10⁹/L; Hb- 86 g/L; ESR- 15 mm/g; Blood protein test: total protein - 48 g/L; albumins - 28 g/L. What indicators of coprological analysis would accompany this syndrom?

A Steatorrhea, creatorrhea
B Large amount of starch grains and cellulose
C Large amount of mucus, amylorrhea
D Large numbers of iodinophilous microbes
E Gas bubbles, acid reaction
105

A 43-year-old woman complains of persistent stomachache with recurrent pain attacks, nausea, repeated vomiting with stagnant bowel content, abdominal distension, and ?atulence. She has been presenting with these signs for 7 hours. Pulse is 116/min. The tongue is dry and brown. The abdomen is symmetrically distemded, soft, painful. Percussion reveals tympanitis. On auscultation there are bowel sounds with metallic overtone, splashing, and dripping. Make the diagnosis:

A Acute intestinal obstruction
B Acute necrotizing pancreatitis
C Acute erosive gastritis
D Acute nonspeci?c colitis
E Acute destructive cholecystitis
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106

After overexposure to cold a 45-year-old woman developed acute pain in her suprapubic and lumbar areas during urination, sharp pains at the end of urination, false urges to urinate. Urine is turbid with blood streaks. The doctor suspects urinary tract infection. What results of laboratory analysis would be the most indicative of such infection?

A Leukocyturia, gross hematuria
B Increased blood creatinine and blood urea
C Daily proteinuria under 3.0
D Daily proteinuria over 3.0
E Gross hematuria
107

A 15-year-old adolescent girl came the the gynecologist with complaints of painful menstruations that are accompanied by nausea, vomiting, and dizziness. Her menarche was at 12. Menstruations became painful since she was 14, remain regular. What treatment should be prescribed in this case?

A Analgesics, antispasmodics, antiprostaglandine therapy
B Antiin?ammatory treatment only
C Vitamin supplements
D Antiandrogen therapy
E Antihemorrhagic agents
108

A 38-year-old patient has been delivered by an ambulance to a surgical department with complaints of general weakness, indisposition, black stool. On examination the patient is pale, there are dotted hemorrhages on the skin of his torso and extremities. On digital investigation there are black feces on the glove. Blood test: Hb- 108 g/L, thrombocytopenia. Anamnesis states that similar condition was observed 1 year ago. Make the diagnosis:

A Rectal tumor
B Hemophilia
C Thrombocytopenic purpura
D Bleeding from an ulcer
E Nonspeci?c ulcerative colitis
109

A 35-year-old patient developed an epileptic attack with tonoclonic spasms that lasted for 3 minutes. After the attack the patient fell asleep but in 5 minutes the second attack occurred. The ?rst step of emergency aid would be to:

A Introduce diazepam intravenously
B Administer chloral hydrate via enema
C Prescribe antiepileptic drugs
D Take blood from the vein for analysis
E Ensure patency of airways
110

A young woman suffering from seborrhea oleosa has numerous light-brown and white spots on the skin of her torso and shoulders. The spots have clear margins, branny desquamation, no itching. What provisional diagnosis can be made?

A Seborrheic dermatitis
B Torso dermatophytosis
C Pityriasis versicolor
D Pityriasis rosea
E Vitiligo
111

A patient is 28 years old. He has been suffering from mental disorder since he was 22. His current condition has changed acutely: for 3 days the patient has been refusing to leave his home. He claims that there is a ”telepathy” occurring between him and other people, through which he receives ”thoughts of strangers” and transmits his own thoughts for everyone to hear. He thinks his thoughts and actions are manipulated through this ”telepathy”. Make the preliminary diagnosis:

A Paranoid schizophrenia
B Acute reaction to stress
C Catatonic episode
D Organic delirium
E Depressive episode
112

A 3-year-old child presents with sharp deterioration of his general condition. He has a history of purulent otitis. His temperature is now 38.5°C. The left leg is pressed to the torso, active movements are absent, the lower third of the thigh and knee joint are thickened, hyperemic, with localized fever. Axial load leads to acute discomfort of the patient. What is the most likely diagnosis?

A Rheumatoid arthritis
B Epiphyseal osteomyelitis on the left
C Left hip fracture
D Hygroma of the knee
E Osteogenic sarcoma
113

A 19-year-old student was urgently hospitalized due to marked dyspnea and chest pain on the left. Her body temperature is 38.8°C. She has been presenting with these signs for 3 days. Respiratory rate is 42/min., shallow. Percussion sound is dull to the left from the center of the scapula, no respiration can be auscultated. The left heart border is displaced outwards by 3 cm. Embryocardia and heart rate of 110/min are observed. Palpation of the right subcostal area is painful. What urgent measures should be taken in this case?

A Administration of cardiac glycosides
B Prescription of penicillin antibiotics
C Urgent thoracocentesis
D Referral into thoracic surgery unit
E Administration of furosemide
114

A 20-year-old woman, gravida 2, para 1 has been in labor for 4 hours. Her condition is satisfactory. Moderately painful contractions occur every 3 minutes and last for 35-40 seconds. The waters have not burst yet. The fetus is in longitudinal position. Fetal heartbeats are 136/min., clear and rhytmic. Major segment of the fetal head is engaged to the pelvic inlet. Vaginal examination shows smooth cervix of 6cm, amniotic sac is intact, sagittal suture is in the left oblique diameter, occipital fontanel is on the right near the symphysis pubis. What stage of the labor is it?

A The second stage of normal labor
B Latent phase of the ?rst stage of normal labor
C Active phase of the ?rst stage of normal labor
D Preliminary stage
E Precursors of childbirth
115

A 1.5-month-old child on breastfeeding presents from birth with daily vomiting, irregular liquid foamy feces, and ?atulence, which are resistant to antibacterial and probiotic therapy; no increase of body mass is observed. The child's condition improved, when breastmilk was substituted. What pathology is it?

A Drug-induced enteritis
B Lactase de?ciency
C Functional dyspepsia
D Intestinal lambliasis (Giardiasis)
E Infectious enteritis
116

A 72-year-old man complains of lower extremity edema, sensation of heaviness in the right subcostal area, dyspnea in rest. For over 25 years he has been suffering from COPD. Objectively: orthopnea, jugular venous distention, diffuse cyanosis, acrocyanosis. Barrel chest is observed, on percussion there is vesiculotympanitic (bandbox) resonance, sharply weakened vesicular respiration on both sides, moist crepitant crackles in the lower segments of the lungs. Heart sounds are weakened, the II heart sound is accentuated over the pulmonary artery. The liver is +3 cm. What complicated the clinical course of COPD in this patient?

A Pulmonary embolism
B Community-acquired pneumonia
C Acute left ventricular failure
D Diffuse pneumosclerosis
E Chronic pulmonary heart
117

A burn victim with ?ame burns of the IIIA-B and IV degrees on his face, neck, and anterior surface of the thorax was brought into the admission room. The hairs in his nostrils are burnt, his labial and glossal mucosa are gray-white. The voice is hoarse; respirations are frequent and shallow; the patient has trumpetlike cough that produces soot-streaked sputum. The signs of respiratory failure were progressing, while the patient was being transported into the intensive care unit. What emergency care must be provided to this patient?

A Administration of respiratory analeptics
B Intubation of the trachea and mechanical ventilation
C Administration of bronchial spasmolytics
D Tracheostomy
E Inhalation of moisturized oxygen
118

A 72-year-old man with pnaumonia complains of marked dyspnea, chest pain, severe cough with expectoration, to is 39.540°C, no urination for a whole day. Objectively the patient is conscious. Respiratory rate is 36/min. Over the right lower pulmonary lobe percussion sound is dull; on auscultation there is bronchial respiration and numerous moist crackles. Blood pressure is 80/60 mm Hg. Heart rate is 120/min. Heart sounds are muf?ed, there is tachycardia. What tactics should the family doctor choose in the management of this patient?

A Hospitalization into intensive care unit
B Hospitalization into neurology unit
C Outpatient treatment
D Hospitalization into pulmonology unit
E Treatment in the day patient facility
119

Estimation of community health level involved analysis of a report on diseases registered among the population of district under charge (reporting form 12). What index is calculated based on this report?

A Prevalence
B Index of pathological affection
C Index of hospitalized morbidity
D Index of basic non-epidemic morbidity
E Index of morbidity with temporary disability
120

A 72-year-old woman suffers from diabetes mellitus type II, concomitant diseases are stage II hypertension and stage IIB heart failure. She takes metformin. Hypertensic crisis had occurred the day before, after which the patient developed extreme weakness, myalgias, thirst, dry mouth, polyuria. BP is 140/95 mm Hg, heart rate is 98/min., no edemas or smell of acetone detected. What measures should be taken to prevent development of comatose state in the patient?

A Apply hypotonic solution of sodium chloride
B Double the dosage of metformin
C Stop metformin, prescribe short-acting insulin
D Additionally prescribe long-acting insulin
E Prescribe glibenclamide
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121

The body of a 24-year-old woman with probable signs of poisoning has been found on the street. Forensic medical examination was requested by an investigator during examination of the site and the body. According to the Criminal Procedure Code currently in force in Ukraine, forensic medical examination is required when it is necessary to determine the:

A Mechanism of death
B Time of death
C Mode of death
D Cause of death
E Manner of death
122

It is the 3rd day after the normal term labor; the infant is rooming-in with the mother and is on breastfeeding. Objectively: the mother's general condition is satisfactory. Temperature is 36.4°C, heart rate is 80/min., BP is 120/80 mm Hg. Mammary glands are soft and painless; lactation is moderate, unrestricted milk ?ow. The uterus is dense, the uterine fundus is located by 3 ?ngers width below the navel. Lochia are sanguino-serous, moderate in volume. Assess the dynamics of uterine involution:

A Subinvolution
B Hematometra
C Physiological involution
D Pathologic involution
E Lochiometra
123

A 27-year-old man was hospitalized in severe condition 50 minutes after receiving a penetrating wound to the left side of the chest. Objectively the patient is in a stupor, his skin is pale and acrocyanotic. Pulse is 120/min., of poor volume, weak. Blood pressure is 80/40 mm Hg. Heart sounds are muf?ed, cardiac borders are markedly expanded. In the III intercostal area along the parasternal line on the left there is a stab-incised wound. Plain chest X-ray shows enlarged heart shadow with smoothed out waist of the heart, there is hemothorax on the left to the 5th rib. What contributes the most to the severity of the patient's condition?

A Blood loss
B Cardiac rhythm disturbance
C Hemothorax and acute respiratory failure
D Acute heart failure
E Cardiac tamponade
124

A 59-year-old patient suffering from hypertension was delivered to the hospital with complaints of acute headache, nausea, recurrent vomiting. On examination she presents with acute meningeal symptom complex. BP is 185/105 mm Hg. What additional examination would you recommend to the patient in the ?rst place?

A Electroencephalography
B Lumbar puncture
C Echoencephalography
D Ventriculopuncture
E Rheoencephalography
125

During regular examination of a 2-yearold boy, he presents with enlarged left kidney, painless on palpation. The right kidney was undetectable on palpation. Excretory urography shows no contrast on the right. Cytoscopy detected hemiatrophy of the urinary bladder trigone, the right ureteral ori?ce is not detected. What pathology is it?

A Agenesis of the right ureter
B Hypoplasia of the right kidney
C Dystopia of the right kidney
D Agenesis of the right kidney
E Ectopic right ureteral ori?ce
126

A 5-year-old child has body temperature risen up to febrile numbers, suffers from inertness, weakness. Examination revealed hemorrhage on the skin of limbs and torso. Enlargement of cervical and axillary lymph nodes can be detected. The liver is 4 cm below the costal arch; the spleen is 6 cm below the costal arch. Blood test: erythrocytes - 2.3 × 10¹²/L, Hb- 60 g/L, platelets - 40 × 10⁹/L, leukocytes - 32.8 × 10⁹/L, eosinophiles - 1%, band neutrophiles - 1%, segmented neutrophiles - 12%, lymphocytes - 46%, monocytes - 1%, blasts - 40%, Duke's bleeding time test result is 9 min. What examination is necessary to make the diagnosis?

A Myelogram (bone marrow biopsy)
B Lymph nodes biopsy
C Analysis of dynamic platelet function
D Abdominal US
E Detection of hepatitis markers
127

A 36-year-old man complains of marked dyspnea and cardiac pain. He ascribes his disease to the case of in?uenza that he had 2 weeks ago. Objectively he leans forward when sitting. The face is swollen, cyanotic, cervical veins are swollen. Heart borders are extended on the both sides, heart sounds are muf?ed, heart rate = Ps = 118/min., BP is 90/60 mm Hg. Blood test: ESR is 16 mm/hour. ECG shows low voltage. X-ray shows trapezoidal cardiac silhouette and signs of pulmonary congestion. Choose the treatment tactics:

A Glucocorticosteroids
B Pericardectomy
C Antibiotics
D Pericardial puncture (pericardiocenthesis)
E Diuretics
128

A 25-year-old patient is not married and has sexual relations with several partners. During the last 3 months he noticed small amount of mucoserous secretions produced from urethra. Subjectively: periodical itching or burning pain in urethra. Two months ago pain in knee join developed. Possibility of trauma or exposure to cold is denied by the patient. During the last week eye discomfort is noted - lacrimation and itching. What provisional diagnosis can be suggested?

A URTI with conjunctiva and joints affected
B Bacterial nonspeci?c urethral conjunctivitis
C Reactive arthritis
D Rheumatoid arthritis
E Seasonal pollinosis
129

A woman complains of weight gain, chills, edema, xeroderma, somnolence, dif?culties with focusing. Objectively: height is 165 cm; weight is 90 kg; body proportions are of female type, to- 35,8°C, heart rate - 58/min., BP105/60 mm Hg. Heart sounds are weakened, bradycardia is observed. Other internal organs have no alterations. Thyroid gland cannot be palpated. Milk secretion from mammary glands is observed. Hormone test revealed increased levels of thyroid-stimulating hormone (TSH) and prolactin, and decreased level of thyroxine (?4). What is the cause of obesity?

A Hypopituitarism
B Adiposogenital dystrophy
C Prolactinoma
D Secondary hypothyroidism
E Primary hypothyroidism
130

A 54-year-old patient complains of weakness, jaundice, itching skin. Disease onset was 1.5 months ago: fever up to 39°C appeared at ?rst, with progressive jaundice developed 2 weeks later. On hospitalisation jaundice was severely progressed. Liver cannot be palpated. Gallbladder is enlarged and painless. Blood bilirubin is 190 mcmol/L (accounting mainly for direct bilirubin). Stool is acholic. What is the most likely reason for jaundice in this patient?

A Mechanical jaundice
B Hemolytic jaundice
C Hepatocellular jaundice
D Caroli syndrome
E Gilbert's syndrome
131

A 23-year-old man came to the surgeon with complaints of pain, redness of the skin, and swelling in the area of his proximal interphalangeal joint of the III ?nger on the right hand. Six days ago he pricked his ?nger with a wire. Objectively the III ?nger on the right hand is swollen, hyperemic, prominent in the projection of interphalangeal joint, sharply painful on touch and during movements. Finger mobility is reduced. Fluctuation sign is present. What diagnosis corresponds to the given clinical presentation?

A Finger furuncle
B Articular panaritium
C Pandactylitis
D Bone panaritium
E Subcutaneous panaritium
132

A 28-year-old woman complains of nausea, stomachache, pain in her tongue, and liquid feces. Three days ago she ate poorly salted pike caviar. Objectively her skin is pale, the tongue looks ”lacquered” (bald tongue). Pulse is 100/min., with muf?ed heart sounds and systolic murmur over the cardiac apex. Blood pressure is 95/50 mm Hg. The liver is enlarged by 3 cm. Hemogram shows anemia, eosinophils - 18%. Oval helminth eggs were detected in feces. Make the provisional diagnosis:

A Taeniarhynchosis
B Te n i a s i s
C Diphyllobothriasis
D Ascaridiasis
E Trichinosis
133

A 30-year-old woman complains of milk discharge from her breasts and no menstruation for the last 5 months. One physiologic childbirth was 4 years ago. There are no maldevelopments of mammary glands. Bimanual examination revealed diminished uterus and normal sized ovaries. MRIscan shows no brain pathologies. Thyroidstimulating hormone is within normal limits. Serum prolactin is high. What is the most likely diagnosis?

A Polycystic ovaries
B Hypothyroidism
C Sheehan's syndrome (postpartum hypopituitarism)
D Pituitary adenoma
E Hyperprolactinemia
134

A 25-year-old woman during selfexamination detected a tumor in the upper external quadrant of her right mammary gland. On palpation: painless, dense, mobile growth 2 cm in diameter is detected in the mammary gland; no changes in the peripheral lymph nodes are observed. On US of the mammary glands: in the upper external quadrant of the right mammary gland there is a space-occupying lesion of increased echogenicity 21х18 mm in size. The most likely diagnosis is:

A Fibrous adenoma
B Mastitis
C Breast cyst
D Diffuse mastopathy
E Breast cancer
135

A 45-year-old woman underwent one year ago mastectomy followed by chemo- and radiation therapy. She now complains of dyspnea at rest and temperature up to 37.2°C. Her general condition is severe, acrocyanosis is observed. The right side of her chest practically does not participate in respiration. Percussion reveals a dull sound below the 3rd rib; auscultation detects acute weakening of the respiratory sounds. Pleural puncture on the right has yielded a large amount of hemorrhagic exudate. What complication has developed in the patient?

A Acute right-sided pleuropneumonia
B Pulmonary embolism
C Acute pleural empyema
D Right lung abscess
E Carcinomatous pleuritis
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136

A 37-year-old man suffers from attacks of unconsciousness, dyspnea during physical exertion, periodical sensations of heart rate disorder. Father of the patient died suddenly at the age of 45. Objectively: heart rate is 90/min., BP is 140/90 mm Hg. On heart US: ejection fraction - 55%, signi?cant myocardium thickening of the left ventricle and interventricular septum. What drug should be prescribed for the treatment?

A Phenyhydinum (Nifedipine)
B Furosemide
C Bisoprolol
D Hydrochlorothiazide
E Enalapril
137

A 60-year-old man complains of discomfort when swallowing solid food, which he has been observing for a month. He changed his diet to semiliquid food products. At ?rst the discomfort had abated but later it renewed despite the change in the diet. The patient developed gaseous eructation and hoarse voice. What examination should be performed to clarify the diagnosis?

A Diurnal variations of ECG parameters
B Esophagoscopy with biopsy
C Esophageal pH monitoring
D Urea breath test for H. pylori
E Abdominal US
138

A 22-day-old infant developed subcutaneous red nodes from 1.0 to 1.5 cm in size on the scalp; later the nodes suppurated. Temperature increased up to 37.7°C, intoxication symptoms appeared, regional lymph nodes enlarged. Complete blood count: anemia, leukocytosis, neutrocytosis, increased ESR. What diagnosis will you make?

A Pseudofurunculosis
B —
C Scalp phlegmon
D Vesiculopustulosis
E Pemphigus
139

A 32-year-old woman complains of general fatigue, low-grade fever persisting for 4 months, lumbar pain, and dysuria. Anamnesis includes frequent acute respiratory diseases, overexposure to cold, lowcalorie diet, a case of pulmonary tuberculosis in childhood. Clinical urine analysis: pH4.8, leukocyturia, hematuria. Complete blood count: leukocytosis, lymphocytosis, increased ESR. Urography concludes: dilatation of renal pelvis and calyceal system of both kidneys, foci of calci?cation in the projection of right kidney parenchyma. What is the most likely diagnosis?

A Chronic pyelonephritis
B Right renal cyst
C Right renal carcinoma
D Acute glomerulonephritis
E Nephrotuberculosis
140

A 45-year-old woman came to the maternity clinic with complaints of periodical pains in her mammary glands that start 1 day before menstruation and stop after the menstruation begins. Palpation of the mammary glands detects diffuse nodes predominantly in the upper outer quadrants. What is the most likely diagnosis?

A Fibrocystic mastopathy
B Breast cancer
C Hyperprolactinemia
D Breast cyst
E Mastitis
141

A woman complains of temperature increase up to 39°C, sharp pains in her lower abdomen, and sanguinopurulent discharge from her genital tracts. From her case history it is known that 6 days ago she underwent illegal abortion. Objectively her blood pressure is 100/60 mm Hg, pulse is 110/min. Abdominal rigidity, rebound tenderness (Bloomberg's sign), and painful palpation of the lower abdomen are observed. On bimanual examination the uterus is enlarged up to 7 weeks of pregnancy, painful, and soft; posterior vaginal fornix overhangs. Make the diagnosis:

A Metroendometritis
B Pyosalpinx
C Acute adnexitis
D Endometritis
E Pelviperitonitis
142

An 8-year-old girl with complaints of painful urination, frequent low-volume urination, and leukocyturia was diagnosed with acute cystitis. 10 days before the disease onset she was treated by the gynecologist for acute vulvitis. 5 days ago she presented with mild catarrhal symptoms. Her mother ascribes the child's disease to her overexposure to cold. Specify the most likely infection route:

A Lymphogenic
B Descending
C Hematogenic
D Contact
E Ascending
143

A 74-year-old patient visited a urologist with complaints of pain above the pubis and inability to urinate for 8 hours. At home he had taken antispasmodics and had a warm bath but no improvement occurred. Objectively: abdomen is soft and painful above the pubis; dullness of percussion sound is observed above the pubis. Murphy's (Pasternatski's) punch sign is negative on the both sides. What condition does the patient have?

A Chronic urinary retention
B Paradoxal ischuria
C Acute urinary retention
D Anuria
E Oliguria
144

An excavator operator with 20 years of work experience at the opencast ore mine undergoes regular medical examination. He presents with signs of pneumoconiosis. What type of pneumoconiosis is the most likely in this case?

A Anthracosis
B Siderosis
C Silicosis
D Silicatosis
E Asbestosis
145

A 55-year-old woman came to a gynecologist with complaints of leukorrhea and bloody discharge from the vagina after 5 years of menopause. Anamnesis states no pregnancies. Bimanual examination: the uterus and uterine appendages are without changes. During diagnostic curettage of the uterine cavity the physician scraped off enchephaloid matter. What is the most likely diagnosis in this case?

A Ovarian carcinoma
B Cervical carcinoma
C Endometrial carcinoma
D Subserous uterine myoma
E Adenomyosis
146

A 5-year-old boy complains of severe dyspnea and sensation of lack of air. Objectively the child assumes orthopneic position, presents with marked peripheral cyanosis, drumstick ?ngers, nail plates resembling a ”clock face”, the borders of cardiac dullness are bilaterally extended; coarse systolic murmur can be detected over the whole surface of the heart and is especially pronounced in the II intercostal area on the left near the sternum. What disease can be characterized by such presentations?

A Dilated cardiomyopathy
B Defect of the interventricular septum
C Fallot's tetrad
D Defect of the interatrial septum
E Primary bacterial endocarditis
147

A 10-year-old boy is delivered into a polytrauma unit after he received a blunt trauma of the thorax, having fallen from the bicycle. Upon hospitalization his blood pressure is 110/80 mm Hg, heart rate is 96/min. Chest X-ray is noncontributive to the diagnosis. Echocardiogram shows free liquid in the pericardial cavity, in the amount of up to 100 ml. In an hour after the hospitalization the patient started to develop increasing signs of heart failure: jugular venous distention, decreased blood pressure down to 90/70 mm Hg, tachycardia up to 120/min. On auscultation muf?ed heart sounds. What would be the primary tactics of a physician?

A Diuretics intravenously
B Constant oxygenotherapy
C Antibiotics intravenously
D Cardiac glycosides intravenously
E Pericardiocentesis (pericardial puncture)
148

A patient has gradually lost consciousness. The skin is pale and dry. There is smell of ammonia from the mouth. Respirations are deep and noisy. Heart sounds are muf?ed, pericardial friction rub is present. Blood pressure is 180/130 mm Hg. Blood test: Нb- 80 g/L, leukocytes - 12 × 10⁹/L, blood glucose - 6.4 mmol/L, urea - 50 mmol/L, creatinine - 1200 mcmol/L, blood osmolality - 350 mOsmol/kg H2O. No urinary excretion. Make the diagnosis:

A Hyperosmolar coma
B Hyperglycemic coma
C Uremic coma
D Acute renal failure
E Acute disturbance of cerebral circulation
149

A 26-year-old woman has been undergoing treatment for community-acquired pneumonia for 10 days. It is known that her husband had been treated for drug addiction. Sequential intravenous administration of Amoksiklav (Amoxicillin+Clavunate) + Levo?oxacin combination and vancomycin in the prescribed dosage was ineffective. Within the last two days the patient's dyspnea and intoxication acutely exacerbated, bilateral pulmonary in?ltrates are observed. What is the most likely cause of the medication ineffectiveness?

A Idiopathic ?brosing alveolitis
B HIV infection and pneumocystic pneumonia
C Tuberculosis mycobacterium infection with development of tuberculosis
D Infection with polyresistant bacterial strains
E Cancer metastases in the pulmonary tissues
150

A 35-year-old man complains of persisting enlargement of his peripheral lymph nodes that cause him no discomfort. The case history states that the ?rst lymph nodes to enlarge were cervical, supraclavicular, and axillary; new groups of lymph nodes emerged. Objectively the lymph nodes are soft and elastic on palpation, enlarged, painless, not ?xed to the surrounding tissue. What examination method would be the most informative for early diagnostics of this disease?

A X-ray
B Radioisotope scanning of the skeleton
C Needle biopsy
D Magnetic resonance tomography
E Ultrasound
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151

A 32-year-old woman complains of body weight loss despite her increased appetite, nervousness, and tremor of the extremities. Objectively: the skin is moist; the thyroid gland is diffusely enlarged, painless, soft, and mobile. Blood test: increased level of T3, T4, and decreased thyroid-stimulating hormone (TSH). What is the most likely diagnosis?

A Diffuse toxic goiter
B Thyroid adenoma
C Thyroid carcinoma
D Diffuse nontoxic goiter
E Autoimmune (Hashimoto's) thyroiditis
152

A 64-year-old man suddenly sensed pain in his occipital area, dizziness, general weakness. He has a 15-year-long history of hypertension. Objectively the skin and mucosa are of normal color. Auscultation reveals vesicular respiration across the lung surface. At the cardiac apex the I heart sound is weakened, the II heart sound is accentuated over the aorta. Pulse is 84/min., blood pressure is 180/100 mm Hg. Other body organs and systems are unaffected. What drug should be prescribed in the ?rst place?

A Amlodipine
B Captopril
C Perindopril
D Ramipril
E Urapidil
153

During winter epidemics of in?uenza caused predominantly by virus А/California/04/2009 (H1N1), on the 2nd day after the disease onset a 30-year-old hospitalized man presented with high fever, dry cough, myalgia, headache, and general weakness. What should be prescribed as etiotropic treatment in this case?

A Immunoglobulin
B Acyclovir
C Interferon inducers
D Antibiotics
E Neuraminidase inhibitors (Oseltamivir)
154

A 24-year-old pregnant woman on her 37th week of pregnancy has been delivered to a maternity obstetric service with complaints of weak fetal movements. Fetal heartbeats are 95/min. On vaginal examination the uterine cervix is tilted backwards, 2 cm long, external ori?ce allows inserting a ?ngertip. Biophysical pro?le of the fetus equals 4 points. What tactics of pregnancy management should be chosen?

A Doppler measurement of blood velocity in the umbilical artery
B Treatment of fetal distress, if ineffective, then elective cesarean section on the next day
C Urgent preparation of the uterine cervix for delivery
D Urgent delivery via cesarean section
E Treatment of placental dysfunction and repeated analysis of the fetal biophysical pro?le on the next day
155

During regular preventive gynecological examination a 30-year-old woman was detected to have dark blue punctulated ”perforations” on the vaginal portion of the uterine cervix. The doctor suspects endometriosis of the vaginal portion of the uterine cervix. What investigation method would be most informative for diagnosis con?rmation?

A US of the lesser pelvis
B Curettage of the uterine cavity
C Colposcopy, target biopsy of the cervix
D Hysteroscopy
E Hormone testing
156

A 26-year-old woman came to a gynecologist for a regular check-up. She has no complaints. Per vaginum: the uterus lies in ante?exion, not enlarged, dense, mobile, painless. On the left from the uterus in the area of uterine appendages there is a mobile painless outgrowth that can be moved independently from the uterus. On the right the appendages cannot be detected. What additional investigation would be informative for diagnosis clari?cation?

A Colonoscopy
B Examination for urogenital infection
C Ultrasound of the lesser pelvis
D Colposcopy
E Metrosalpingography
157

A 38-year-old man underwent surgical treatment of a wound with a suppuration focus. On the 8th day after the procedure the wound cleared of purulo-necrotic discharge and granulations appeared. However, against the background of antibacterial therapy, the patient's body temperature persists as high as 38.5-39.5°C; chills, excessive sweating, and euphoria are observed in the patient; heart rate is 120/min. What complication of the local suppurative in?ammatory process can be suspected?

A Trombophlebitis
B Purulent-resorptive fever
C Meningitis
D Pneumonia
E Sepsis
158

A man complains of high fever, pain in the area of his right mastoid bone, and purulent discharge from the right ear. One week ago he had a case of URTI. Objectively the right auricle protrudes, the skin behind the ear is hyperemic and pastose; on palpation of the mastoid bone the pain intensi?es; the auditory meatus is ?lled with thick pus, posterosuperior meatal wall sags; the tympanic membrane is red and perforated. Make the diagnosis:

A Acute otitis media
B Furuncle of the external auditory meatus
C Acute mastoiditis
D Acute otitis externa diffusa
E Exacerbation of chronic mesotympanitis
159

A 52 year old man came to see his family physician complaining of pain in the chest. After taking history and performing physical exam the doctor decided to direct the patient to cardiologist for a consultation. What level of medical care is being proposed to the patient?

A Tertiare healtcare
B Palliative care
C Emergency healthcare
D Secondary healthcare
E Primary healthcare
160

A 30-year-old woman made an appointment with the family doctor for scheduled vaccination of her 2-year-old child. What type of healthcare provides such medical services?

A Emergency aid
B Primary healthcare
C Tertiary healthcare
D Palliative care
E Secondary healthcare
161

A 28-year-old man after car accident received a wound to the right side of his chest in?icted by a sharp metal object. A foamy liquid ?ows out from the wound, there are tympanitis and acutely weakened respirations in the right. Blood pressure is 70/30 mm Hg, pulse is 120/min., Hb is 28 g/L. X-ray shows collapsed right lung, horizontal ?uid level is at the 3rd rib. What treatment tactics should be chosen?

A Conservative therapy
B Delayed thoracotomy
C Urgent thoracotomy
D Apply occlusive dressing to the wound
E Drain the right pleural cavity
162

A 38-year-old woman has been working as a milker for 15 years. She made an appointment with the doctor due to development of red rashes on her hands, predominantly in the interdigital space. The rashes are weeping, itching, and expanding on her skin. Examination of her hands shows her nail plates to be yellow and brittle. These presentations aggravate during work. Make the provisional diagnosis:

A Pemphigus
B Dermatophytosis
C Scabies
D Pyoderma
E Occupational eczema
163

An 18-year-old patient complains of skin rash. The patient has been suffering from this condition for 5 years. The ?rst instance of this disease occurred after a car accident. Objectively: the patient presents with papular rash covered in silvery scales, ”thimble” symptom (small pits on the nails), affected joints. What is the most likely diagnosis?

A Lupus erythematosus
B Psoriasis
C Rheumatism
D Onychomycosis
E Panaritium
164

A postparturient woman, who has been breastfeeding for 3 weeks, made an appointment with the doctor. For the last 6 days she has been feeling unwell, complains of body temperature of 38-39°C, general weakness; within the last 2 days she developed pain and redness in the area of her right mammary gland. Examination revealed her mammary gland to be signi?cantly enlarged and deformed; breast tissue ?uctuations and lymphadenitis are observed. What type of mastitis is the most likely?

A Phlegmonous mastitis
B Serous mastitis
C Lactostasis
D Mammary edema
E In?ltrative mastitis
165

When her car collided with a tree, a 37year-old woman felt sharp pain in her left hip joint. She was unable to get out of the car. Her position is forced, the hip is pressed to the abdomen, ?xed, and rotated inwards; the limb is ?exed in the knee, any attempt to change the position results in sharp pain. Make the diagnosis:

A Closed cervical fracture of the left hip
B Contusion of the left hip joint
C Arthritis of the left hip joint
D Closed dislocation of the left hip
E Hemarthrosis of the left hip joint
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166

On the 9th day after childbirth the obstetric patient developed high fever up to 38°C. She complains of pain in the right mammary gland. The examination revealed the following: a sharply painful in?ltrate can be palpated in the right mammary gland, the skin over the in?ltrate is red, subareolar area and nipple are swollen and painful. What is your diagnosis?

A Cancer of the right mammary gland
B Fibrous cystic degeneration of the right mammary gland
C Abscess of the right mammary gland
D Mastopathy
E Serous mastitis
167

During reanimation procedures an attempt to intubate trachea was made. Neither glottis nor epiglottis can be visualized via laryngoscopy. What tactics should be chosen in this case?

A Continue the attempts until the intubation is successful
B Insert a laryngeal mask
C Discontinue the attempts for mechanical ventilation
D Temporarily cease the chest compressions to make intubation easier
E Perform a bag-valve-mask ventilation with Ambu bag
168

A 48-year-old woman developed insomnia, depressive mood, anxiety, fears and suicidal thoughts after the death of her husband that occurred one month ago. During her stay in the hospital she speaks in a low voice, is depressed, anxious, avoids sleeping, refuses to eat. What medications should be prescribed in this case?

A Antipsychotics
B Nootropics
C Anticonvulsants
D Antidepressants
E Group B vitamins
169

A 39-year-old man suffers from chronic adrenal insuf?ciency and receives replacement glucocorticoid therapy (hydrocortisone - 15 mg/day). He is to undergo elective surgery for calculous cholecystitis. What medication adjustment should be made on the day of the surgery to prevent the development of acute adrenal insuf?ciency?

A Add antibiotic
B Prescribe large volume intravenous ?uid infusion
C Cancel the drug for the day of the surgery
D Add mineralocorticoid
E Increase the dosage by 2-3 times
170

A 22-year-old man at 18:00 developed persisting dull pain in the epigastrium. Three hours later nausea appeared, he vomited once. By the morning the pain shifted to the right iliac area. Body temperature rose to 38.6°C, developed tachycardia of 110/min. On examination there are muscle rigidity and Bloomberg's sign (rebound tenderness) in the right iliac area of the anterior abdominal wall. Plain x-ray of the abdomen shows no ?uid levels, free air under the diapragm on the right. Make the diagnosis:

A Acute cholecystitis
B Renal colic
C Perforation of a gastric ulcer
D Acute pancreatitis
E Acute appendicitis
171

40-50 minutes after the completion of repair works conducted in a closed garage, with car engine running, the repair workers developed severe headache in the temporal area, nausea, tinnitus, vertigo, etc. These symptoms are characteristic of acute poisoning with:

A Fluoride
B Organochlorides
C Aldehydes
D Hydrogen sul?de
E Carbon monoxide
172

After a long drive with the window open a man developed facial asymmetry; he cannot close his right eye, his right nasolabial fold is smoothed out, movements of expression are absent on the right, there is a disturbance of gustatory sensation in the tongue on the right. No other neurological pathologies were detected. What disease can be provisionally diagnosed in this patient?

A Ischemic stroke
B Neuropathy of the trigeminal nerve
C Neuropathy of the facial nerve
D Neuropathy of the oculomotor nerve
E Trigeminal ganglionitis
173

On ultrasound of the thyroid gland, a 47year-old woman presents with a hypoechoic node 1.6 cm in diameter with blurred margins and intranodular hypervascularization. The doctor suspects thyroid carcinoma. What method should be used to verify the diagnosis?

A Determine TSH level in the blood
B Positron emission tomography (PET)
C Case monitoring
D Thyroid scintigraphy
E Fine-needle aspiration biopsy
174

A 19-year-old young man complains of cough with expectoration of purulent sputum in amount of 100 ml per day, hemoptysis, dyspnea, increased body temperature up to 37.8°C, general weakness, weight loss. The patient's condition has been persisting for 4 years. Exacerbations occur 2-3 times per year. The patient presents with malnutrition, pale skin, cyanosis of the lips, drumstick (clubbed) ?ngers. Tympanic percussion sound in the lungs, weakened respiration, various numerous moist crackles in the lower pulmonary segments on the left can be observed. In blood: erythrocytes - 3.2 × 10¹²/L, leukocytes - 8.4 × 10⁹/L, ESR- 56 mm/hour. On X-ray: lung ?elds are emphysematous, the left pulmonary root is deformed and dilated. What is the most likely diagnosis?

A Chronic left-sided pneumonia
B Suppuration of the cyst in the left lung
C Left-sided pulmonary cystic dysplasia
D Chronic abscess of the left lung
E Multiple bronchiectasis of the left lung
175

An 8-year-old child presents with blood pressure up to 180/100 mm Hg in the upper limbs accompanied by headaches, tinnitus, occasional nosebleeds, and high fatigability. On examination there is no pulse over the leg arteries. ECG shows left ventricular hypertrophy. MRI-scan shows aortic narrowing to 5 mm in the typical place. Coarctation of aorta is diagnosed. What kind of treatment should be prescribed in this case?

A Physical therapy
B Conservative
C Abstain from surgery in favor of complex conservative therapy
D Surgical
E Case monitoring
176

A 6-year-old girl arrived to the in-patient unit with complaints of enlargement of the lower third of her right thigh. According to the case history, she has been stepping carefully on her right leg and limping for 6 months. Blood test detected anemia. X-ray of the right thigh shows a round bone defect with clear margins resembling melting sugar in the distal metaphysis. What provisional diagnosis can be made in this case?

A Osteogenic sarcoma of the right femur
B Tuberculous osteitis of the distal femoral metaphysis on the right
C Acute hematogenous osteomyelitis of the distal femoral metaphysis on the right
D Rheumatoid arthritis of the right knee joint
E Giant cell tumor of the right femur
177

A 37-year-old man working as a typesetter in a print shop complains of rapid fatigability, paroxysmal attacks of stomachache, weak drooping hands. Examination of neurological status revealed hypotrophy of the forearm muscles. Carporadial re?exes are sharply weakened. Sensitivity is not disturbed. Gums present with dark blue border. What neurological pathology is it?

A Guillain-Barre syndrome (postinfectious polyneuritis)
B Lead polyneuropathy
C Shingles
D Brachial plexitis
E Ulnar neuropathy
178

The mother of an epileptic son complains of her son periodically presenting with irritable depression, when he becomes excited and prone to physical agression and violence. These moods last for 5-10 minutes, after which the patient exhausts himself and falls asleep. Upon waking he is depressed, sad, cannot recall his actions or recalls them only partially. What psychopathologic condition is it?

A Ambulatory automatism
B Epileptic delirium
C Dysphoria
D Dysthymia
E Pathologic affect
179

A 44-year-old woman has undergone subtotal thyroid resection due to diffuse toxic goiter. On the second day after the surgery the patient's condition deteriorated; she developed palpitations, dyspnea, sweating, and diarrhea, and became fearful The patient is anxious, her skin is moist and hot to the touch. Her temperature is 39.2°C. Heart sounds are muf?ed, tachycardia is observed, pulse is 160/min., blood pressure is 85/40 mm Hg. The stomach is soft and painless. What should be measured to clarify the patient's condition?

A Blood sugar
B Thyroid hormones
C 17-KS and 17-OCS in urine
D Blood epinephrine and norepineprine
E Serum transaminases
180

The dermatologist has an appointment with a 30-year-old man that complains of severely itching rashes that especially disturb him at night. The rashes developed 2 weeks ago, after he had returned from a travel. Objectively on the lateral surfaces of his ?ngers, hands, wrists, elbows, lower abdomen, genitals, and thighs there are paired papulovesicles, single pustules, and scratch marks. What disease can be suspected?

A Dermatitis
B Eczema
C Scabies
D Shingles
E Pyoderma
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181

A 28-year-old man, a teacher, after emotional stress developed painful muscle spasms in his right hand that occur during writing; now he has to hold the pen between the second and third ?ngers. He has no problems with typing or writing on the blackboard; no other motor disturbances or neurological pathologies are detected. What is the most likely diagnosis?

A Cortical agraphia
B Neuropathy of the right radial nerve
C Parkinsonism
D Writer's cramp
E Neuropathy of the right ulnar nerve
182

A 32-year-old pregnant woman at the term of 5-6 weeks was vaccinated against in?uenza along with her whole family. At that time she was not aware of her pregnancy. The pregnancy is wanted. The woman needs an advice from the family doctor regarding the maintenance of her pregnancy, namely whether there is a risk of fetal malformations because of received vaccination. What advice should the doctor give in this case?

A Test for antibodies against in?uenza virus is necessary
B Therapeutic abortion is recommended
C Vaccination against in?uenza is safe during pregnancy
D An infectious diseases specialist must be consulted
E Immediate ultrasound of the lesser pelvis is necessary
183

A 15-year-old girl suffers from systemic lupus erythematosus and has been receiving prednisolone therapy in the daily dosage of 2 mg/kg for the last 6 weeks. The plans are made to gradually lower the dosage of the medicine. No clinical signs of her disease are observed. Previously she has received no immunization against measles. Due to measles outbreak it is necessary to develop the immunity against this infection in the patient. When can she be vaccinated?

A Never due to medical contraindications
B 1 month after the prednisolone therapy is complete
C Immediately after the prednisolone therapy is complete
D After 2 weeks of prednisolone therapy in the dosage lower than 2 mg/kg/24 hours
E At the present time
184

A 45-year-old veterinary worker has made an appointment with the doctor for regular examination. In his duties he frequently deals with animals, however he denies working with rabies-affected animals. Previously he has received no antirabic vaccination. What should the doctor recommend in this case?

A Vaccination in case of contact with sick animal
B Preventive immunization with rabies immunoglobulin
C Administration of antirabic vaccine and rabies immunoglobulin
D Preventive immunization with antirabic vaccine
E Preventive immunization with anti-rabies serum
185

A healthy child 1 year and 5 months of age is being vaccinated against hepatitis B. The child did not receive the ?rst dose of the vaccine previously, while in the maternity hospital. The doctor makes an individual vaccination schedule for this child and plans the administration of the next dose of the vaccine. What is the minimum interval between doses of vaccine in this case?

A 2 months
B 6 months
C 1 month
D 12 months
E 3 months
186

A 46-year-old man came to the surgeon's of?ce. He complains of twitching sensation in the wound on his left foot, insomnia, and anxiety. According to the patient, he received this wound 5 days ago, when he accidentally stepped on a glass shard, while on the beach. He requested no medical assistance. Objectively the patient's general condition is satisfactory, pulse is 75/min., blood pressure is 130/80 mm Hg, temperature is 36.9°C. On the plantar surface of his foot there is a wound 1.5 cm long and up to 3 cm deep. The wound edges are moderately hyperemic, no discharge from the wound is observed. What disease can be suspected in this patient?

A Fasciitis
B Anthrax
C Phlegmon
D Diphtheria
E Tetanus
187

A 45-year-old woman has been suffering from rheumatoid arthritis for 10 years and takes methotrexate twice a week. What statement regarding vaccination against pneumococci (23-valent vaccine) would conform to the recommendations for the management of rheumatoid arthritis issued by the European League Against Rheumatism in 2010?

A Vaccination necessitates increase in the dosage of the long-term medicines
B Vaccination is contraindicated to the patients who take methotrexate
C Vaccination is recommended
D Vaccination is not recommended
E Vaccination is contraindicated in cases when in?ammatory process is active
188

A 65-year-old woman was diagnosed with the following: chronic rheumatic heart disease, I degree of rheumatic activity; combined mitral heart disease with prevalence of III degree stenosis; heart failure IIA with retained left ventricular ejection fraction, functional class III (NYHA). What tactics of vaccination against respiratory infections should be chosen to provide secondary prevention of exacerbations and to avoid heart failure decompensation in this patient?

A Scheduled yearly vaccination against in?uenza and pneumococci
B Any vaccination is contraindicated due to elderly age of the patient
C Any vaccination is contraindicated due to mitral valve disease
D Vaccination is contraindicated due to severe heart failure
E Vaccination should be combined with antibiotic administration
189

A 69-year-old woman was diagnosed with the following: ischemic heart disease; stable exertional angina pectoris, FC III; heart failure IIA with retained left ventricular ejection fraction, functional class III (NYHA). What vaccine should be chosen for in?uenza prevention and to avoid destabilization of the patient's condition?

A Vaccination is contraindicated due to severe heart failure
B Recombinant in?uenza vaccine (RIV)
C Vaccination is contraindicated due to elderly age of the patient
D Inactivated in?uenza vaccine (IIV)
E Type of in?uenza vaccine is not important
190

A 60-year-old man presents with subcompensated viral liver cirrhosis (HCV), Child-Pugh class B. What tactics should be chosen regarding the vaccination against in?uenza in this case?

A In case of in?uenza outbreak
B Combined with antiviral drugs
C Contraindicated due to elderly age of the patient
D Scheduled yearly vaccination
E Contraindicated due to disease progression stage, as shown by Child-Pugh class
191

A 20-year-old student was brought to the ?rst-aid center. He has a closed fracture of the left forearm and a contused lacerated wound on his left shin. After the patient received initial wound management, he presented the documents con?rmingthathehasreceived all the necessary preventive vaccination as scheduled. What should the doctor do to prevent tetanus in this patient?

A Administration of anti-tetanus serum
B Administration of tetanus immunoglobulin
C Administration of tetanus toxoid
D Antibiotic therapy
E Dynamic case monitoring
192

A 17-year-old girl has made an appointment with the doctor. She plans to begin her sex life. No signs of gynecological pathology were detected. In the family history there was a case of cervical cancer that occurred to the patient's grandmother. The patient was consulted about the maintenance of her reproductive health. What recommendation will be the most helpful for prevention of invasive cervical cancer?

A Antiviral and antibacterial drugs
B Vitamins, calcium, omega-3
C Timely treatment of sexually transmitted diseases
D Immunomodulators
E Vaccination against human papillomavirus (HPV)
193

A 6-month-old infant is not vaccinated. The physician recommends a DPT (diphtheria, pertussis, tetanus) vaccination but the mother is absolutely against this procedure. Choose the most substantial argument in favor of vaccination:

A Personal professional experience
B —
C Epidemic risk for the others
D Risk of lethal consequences
E High quality of vaccines
194

In autumn a 45-year-old man was recommended an elective surgery for coronary artery bypass grafting due to multivessel coronary artery disease. The patient has never received anti-in?uenza vaccination. Why would the family doctor offer a scheduled yearly vaccination against in?uenza to this patient?

A Prevention of seasonal in?uenza
B Decrease the risk of mortality due to pneumonia and heart failure
C Primary prevention of in?uenza during postoperative care
D Immunoprophylaxis of postoperative pulmonary complications
E Secondary prevention of exacerbations of chronic ischemic heart disease
195

A 28-year-old woman has made an appointment with the family doctor to receive vaccination against in?uenza. However, having collected the patient's medical history, the doctor claimed this procedure to be absolutely contraindicated for this woman. What anamnestic data is the absolute contraindication to vaccination?

A Pregnancy at 30 weeks
B Psoriasis in the remission phase
C Body temperature - 37.2°C
D Egg white intolerance
E Blood hemoglobin - 109 g/L
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196

A 26-year-old man complains of chills, rhinitis, dry cough, and fever up to 38°C. Examination shows him to be in a moderately severe condition; there are small pale pink non-merging spots on the skin of his back, abdomen, and extremities. Palpation reveals enlarged occipital and axillary lymph nodes. No information about vaccination history could be obtained. What is the likely etiology of this disease?

A Neisseria meningitis
B Streptococcus
C Epstein-Barr virus
D Rubella virus
E Mumps virus
197

During administration of planned DPT vaccination the child suddenly developed acute anxiety, signs of pain response, dyspnea, grunting respirations, cutis marmorata, cold sweat. Objectively the child's consciousness is disturbed, heart rate is 150/min., blood pressure is 60/40 mm Hg, heart sounds are muf?ed. The child was diagnosed with anaphylactic shock. What drug should be administered ?rst?

A Lasix (Furosemide)
B Euphylline (Aminophylline)
C Epinephrine
D Suprastin (Chloropyramine)
E Analgin (Metamizole)
198

Among ?rst-year schoolchildren there was a case of measles registered. A 7-year-old boy from the same group was not vaccinated against measles due to refusal of his parents. His clinical history has no cases of measles in the past and is not contraindicatory to immunobiological agents. Choose the most rational tactics of measles prevention in this schoolboy:

A Isolation for 20 days
B Antibiotics
C Measles-Mumps-Rubella vaccine
D Immunomodulators
E Antiviral agents
199

A 40-year-old man developed fever up to 37.5°C and macular rash 10 days after the ?rst dose of MMR (Measles-Mumps-Rubella) vaccine was administered. The vaccination was considered necessary as there was a measles outbreak in the city and the patient had not received MMR vaccination in his childhood. Is revaccination with MMR vaccine possible?

A Forbidden
B Simultaneously with antihistamines
C After a course of glucocorticoids treatment
D Possible
E Under supervision in the infectious diseases inpatient ward
200

A 26-year-old man is undergoing a regular check-up. One year ago he had a case of tonsillar diphtheria complicated with myocarditis. Presently his condition is satisfactory, no signs of cardiovascular failure; ECG shows ?rstdegree atrioventricular block. What vaccine was administered to this man according to his age?

A Acellular DPT vaccine
B BCG vaccine
C Adsorbed diphtheria tetanus vaccine (modi?ed)
D Oral polio vaccine (OPV)
E Tetanus anatoxin