Крок 2 · Фармація, промислова фармація 2010 · Англійська

For isolation of alkaloids from biological material by Kramarenko's method extract is cleaned. For what operation ammonium sulphate is added to extract?

According to the supply contract with joint-stock company "Darnitsa" , a pharmacy warehouse accepted some inventory items.Which department of the warehouse is directly responsible for the goods acceptance?

A pharmacy analyst supervises the state of a refractometer. For its calibration he needs some distilled water. The distilled water must have the following value of the refractive index:

In order to fill a burrette a pharmaceutist prepared 2 l of 10% benzoate solution. This operation should be recorded in the following register:

months after treatment a patient with coronary heart disease developed tolerance to the prolonged-action nitrates. What drug with nitrate-similar effect should be recommended in this case?

Which of the below-listed drugs is used for thrombolytic therapy in case of myocardial infarction?

On the 4th day of treatment with indometacin a 55-year-old patient developed gastrorrhagia as a result of gastric mucosa ulcer. Ulcerogenic effect of this drug is explained by the lowered activity of the following enzyme:

A patient suffering from peptic ulcer was administered ranitidine. Gastric juice acidity has reduced considerably. What mechanism underlies the action of this drug?

A gravida in her 20th week of gestation fell ill with pneumonia. What chemotherapeutical drug may be administered with no risk for the fetus development?

During a surgical operation the muscle relaxant tubocurarine chloride was used. What antagonist drug should be injected in order to allow the patient to bref independently?

A child has accidentally drunk a solution that was used by his grandmother for glaucoma treatment. The solution turned out to be pilocarpine hydrochloride.What drug can be used as an antidote? 2

A patient with heart failure induced by a long-term coronary vessel disorder can be administered a drug produced out of the following herbal raw material:

A patient came to a drugstore and ordered cowberry leaves. Which of the available herbal raw materials can be offered as a substitute?

In order to identify a polyatomic glycerin alcohol a pharmacy analyst carries out dehydration reaction with potassium hydrosulfate. The generated hereat product has a strong characteristic smell and gives blue colour to the filter paper moistened with 1% solution of sodium nitroprusside and with piperidine. What product is it?

A pharmacy analyst analizes distilled water. For this purpose he brings some amount of the sample material to the boiling point, adds 0,02Msolution of potassium permanganate and diluted sulfuric acid. After 5 minutes of boiling the pink colour of the produced solution should not change. The pharmacy analyst tries to detect the following admixture:

A tablet production unit produces press-coated tablets. What equipment is used for this purpose?

A pharmaceutical enterprise produces a dense extract with 0,25% ammonia solution used as an extractant. This dense extract is:

A pharmacy supplies the population with drugs for cash. Specify the VAT on drugs:

A pharmaceutical enterprise that has achieved high sales rates and customers' recognition will reach the highest profit at the following stage of the product life cycle:

Aerosol production involves application of different groups of propellents. What propellents relate to the group of compressed gases?

Which preparation is the specific antidote in case of intoxication with iron preparations?

A pharmaceutist revealed incompatibility in the formulation. 3 Rp.: Sol. Collargoli 1%- 10 ml Sol. Adrenalini hydrochloridi 0,1%- 1 ml M.D.S. Nasal drops. What chemical process underlies this incompatibility?

A pharmaceutist prepared solution of ethacrydine lactate. What is the peculiarity of this substance dissolving?

A pharmacy produces compounded drugs. What kinds of internal control of drugs production are required?

A pharmaceutist is preparing fatbased suppositories bymethod of pouring. What base is to be used for this purpose?

Preparations on the basis of dandelion roots are recommended for better digestion and as a choleretic because this herbal raw material contains:

Coltsfoot preparations are used for upper airways treatment. During procurement of this herbal raw material the following admixture may appear:

A pharmacist-technologist received an ointment formulation. Rp.: Unguentum Resorcini 1,5% - 10,0 Da. Signa. To be applied on the affected skin areas. The pharmaceutist incorporated dry medical substance into the ointment by the following way:

A pharmacy got an order for eye drops containing 1% solution of pilocarpine hydrochloride. What substance was used in order to ensure isotonicity?

A pregnant woman fell ill with severe pneumonia. What antibacterial drug may be prescribed?

One of the major indicator of drug elimination from the human body is:

It is necessary to make rapid analysis of opiates in urine.Which of the following methods is the most sensitive?

TLC-screening is used for omnidirectional investigation of "acid" chloroform extract. For detection of barbiturates following developers are used:

A pharmacy manager is working out a schedule for a pharmaceutist who is responsible for prescription reception and drug serving out. What is the weekly working time for one employee?

An advance holder (accountant) was given some money from the cash fund of an enterprise for purchase of office accessories. After the cash advance the advance holder must submit the complete application of funds statement no later than:

Ukraine has a valid list of drugs whose price is subject to the governmental regulation. What is the way of retail price formation for Corvalol 25,0 (produced by "Pharmac" ) providing that this drug is included in the above-mentioned list?

For granule drying different types of dryers are used. The dryer SP-30 relates to the following type:

When fenoterolum for inhalations is not available in a pharmacy, it can be substituted by the following drug from the group of bronchoselective beta-2adrenomimetics:

A pharmaceutist prepared some powders whose composition includes camphor. What capsules are required for their packaging?

Mother of a 2-month-old child came to a pharmacy and asked for a febrifuge. What drug should be recommended for the child?

A patient consulted an ophthalmologist about scotopic vision impairment, cornea dryness. What drug was prescribed?

When the glucose is heated with the copper-tartrate reagent (Fehling's reagent) the brick-red precipitate settles down. It indicates presence of the following group:

For the purpose of sales stimulation a pharmaceutical wholesale company grants its customers a discount according to the social contract and on condition of their loyalty. Specify the type of discount: 5

A 6-year-old child with pneumonia was prescribed an antibiotic. After the treatment the child became deaf. Which antibiotic group might have caused this complication?

A patient suffering from hypertension consulted a doctor about dry cough that was presumably provoked by antihypertensive therapy. What antihypertensive drug had she been taking?

According to the requirements of the Ukrainian State Pharmacopoeia, a pharmacy analyst is measuring iron admixture in a preparation by means of citric and thioglycolic acids. What staining indicates presence of this admixture?

Development of advertising strategy for promotion of nonprescription drugs includes identification of the target audience. The highest selectivity of consumer audience can be achieved by means of the following advertisment type:

Choose an optimal antibacterial drug for the mycoplasmal pneumonia treatment:

Emodin, an anthracene derivative, haspurgative effect. Large quantities of anthracene-derived groups of emodin are contained in the fruits of the following plant:

Cardioglycosides of Adonis vernalis are used for heart failure treatment. This plant raw material should be stored:

Theory of management currently marks out four the most important approaches to the management. Choose the approach that is NOT applied in the theory of management:

A pharmacy manager is writing the monthly "Inventory report" . What business transactions should be represented in the expenditure item of the report?

During inventory of a pharmacy the surplus of inventory holdings was revealed. What actions concerning the surplus should be taken by the inventory comission?

Which of the listed preparations should be used as antidote and included into the first-aid kit required at factories where acute intoxications with arsenic, mercury, chrome and bismuth compounds are possible?

A patient has chronic pancreatitis with apparent presentations of pancreatic exocrine hypofunction. Which of the following drugs would be the most appropriate in this case?

On the initiative of the manufacturing company some amendments to a drug information leaflet are to be made for the restriction of the drug use. What type of marketing is applied in this case?

A doctor prescribed an olive oil emulsion whose composition includes anesthesin. In order that anesthesin can be incorpotated into the emulsion it should be dissolved:

Injection solutions of salts derived from weak acids and strong bases require stabilization.What stabilizers are used for these solutions?

О-methylation is an important method of organic substances biotransformation in the body, compounds that are subject to such method contain:

Which antiseptic preparation has bactericidal effect due to the formation of atomic oxygen?

Styles of maize with stigmata containing fatty acids, vitamins, essential oils, saponins and other substances are used as:

Yellow gentian contains bitter glycosides. Raw material of this plant is reccomended for production of drugs with the following effect:

One of the tablet coatings is enterosoluble capsule. They get solved in:

A pharmaceutist-technologist has to prepare a medication with the following formulation: Rp.: Mentholi 0,1 Glycerini 10,0 M.D.S. Nasal drops. What is the reason for their incompatibility?

A pharmacy got an order for a mixture containing manzanita decoction and belladonna extract.What is the reason for their incompatibility?

Two pharmaceutical enterprises simultaneously applied to a bank for establishing a running account. The bank refused the application to one of the enterprises. The reason for the refusal is that the enterprise:

Examination of a patient who has been treated for rheumatoid arthritis for a long time revealed hyperglycemia. What drug might have caused it?

A pharmaceutist prepared eyedrops with boric acid.What sterilization method was applied?

A pharmaceutist refused preparation of nasal drops to a patient because of incompatibility between collargol and dimedrol written in the prescription. What is the reason for incompatibility between these ingredients?

Preparation of multicomponent powders with phenyl salicylate and camphor is accompanied by generation of some fluid. What is the reason for their incompatibility?

A 54-year-old patient who has been suffering from hyperacidic gastritis for several years was prescribed almagel. What pharmacotherapeutical complications on the part of digestive organs may be expected in the first place?

At the initial stage of establishing a pharmaceutical enterprise the internal disciplinary regulations should be adopted. One of the primary matters is the duration of the lunch break for the employees. According to the Labour Code of Ukraine, the break duration must be as follows:

During the analysis of diethyl ether (Aether medicinales) you can determine presence of aldehydes as a specific admixture. Which of the following reragents can be used for determining presence of aldehyde admixture?

A 26-year-old patient was diagnosed with community-acquired pneumonia provoked by mycoplasma. Choose the appropriate antimicrobial preparation for the patient treatment:

A 60-year-old patient has essential hypertension stage II, coronary disease, bronchial asthma. After pharmacotherapy correction the patient exhibited a bronchospastic attack, intensified dyspnea. What drug provoked this complication?

A 70-year-old patient consulted a doctor about elevated arterial pressure. He has a history of benign hyperplasia of prostate. What drug should be administered in this case?

A 67-year-old patient with chronic heart failure takes digoxin. In order to reduce its side effects the patient's doctor recommended to combine it with the followig drug:

A woman who has been treated for infiltrative focal tuberculosis for a long time complains of acute hearing impairment. Which of the following preparations might be the cause of such side effect?

A pharmaceutist revealed incompatibility in a prescription for powders with ascorbic acid and hexamethylenetetramine. What process takes place when these components are combined?

Efficiency of aerosol therapy is to a considerable extent determined by the size of disperse particles. What factor determines the size of aerosol particles during dispersion of an aerosol?

In order to get registered in state authorities pharmacies as legal persons must possess authorized capital stock. What amount is identified as the authorized capital stock?

In the production of injection solutions the activated carbon is used as:

Which of the listed antibacterial drugs should NOT be administered to a patient with diabetes mellitus type II being treated with glibenclamid?

Which of the listed pharmacolgical groups of antihypertensive drugs is contra-indicated the patients with bronchial asthma?

A pharmaceutist prepared a surface action ointment. What ointment base was used? 9

At the end of each month a pharmacy manager writes an Inventory report. This document relates to the following type of accounting:

Preparations of common valerian are used in medical practice as sedative drugs. The main feature that allows to distinguish valerian from the admixtures is:

After a craniocerebral trauma a patient was administered pyracetam. This drug relates to the following pharmacological group:

In order to arrest stenocardia attacks a patient takes nitroglycerin capsules. What is the rational way of the drug introduction?

A patient after bee's stings has angioedema (Quincke's edema). Which drug should be immediately inject to eliminate this condition?

A patient with hypertension was administered metoprolol for the arterial pressure reduction.What is its mechanism of action?

A pharmacy received some medicines from the warehouse. What medicine is subject to the stocktaking in the pharmaceutical institutions?

It is necessary to analyse incrustation of reducing tube after Marsh test for arsenicum to exclude in biological materials compounds of:

An analyst of the National drug quality control inspection identifies "Sulfametoxazol" by adding the solutions of hydrochloric acid, sodium nitrite and beta-naphthol to the preparation. Thereat intense red colour is observed. What functional group is identified by this reaction?

In order to detect an admixture of potassium in medical preparations a pharmacy analyst should carry out a reaction with:

An analyst of the National drug quality control inspection carries out quantitative analysis of "Resorcin" substance by method of bromatometry (back titration). What indicator is used by doing so? 10

A patient with cholelithiasis was prescribed the following drug for the purpose of cholesterol gallstone dissolution:

For thrombosis treatment a patient was prescribed a drug from the group of direct anticoagulants. What drug is it?

A pharmaceutical enterprise produces nitroglycerine tablets.What is the method of their production?

Substances that enter the body subject to various transformations under enzymes influence. What is the direction of mono- and polyatomic alcohol metabolism has the largest toxicological value?

A 68-year-old female patient has been continuously taking furosemide for heart failure treatment.What drug should be used to prevent hypokalemia in patients taking furosemide?

A pharmacy received a prescription for preparation of dermatological ointment with benzylpenicillin. Specify the type of ointment that necessary to prepare:

During production of powders in a pharmacy physiochemical properties of certain ingredients should be taken into consideration. What pharmaceutical substance can be incorporated into the powder mass without additional grinding?

In course of pharmacotherapy of bronchitis a patient was found to have dyspeptic disorders, photodermatitis, liver dysfunction. Which of the prescribed drugs might have caused these manifestations?

A patient who has been suffering from gastric diseases for a long time is found to have hyperchromic anemia.Which of the following drugs is applied for this pathology treatment?

A 25-year-old woman presenting with acute morphine intoxication was given an injection of naloxone that caused rapid improvement of her condition. The mechanism of action of this preparation is based on the block of the following receptors: 11

A phytopreparation "Flacarbinum" has spasmolytic, anti-inflammatory and antiulcer effect. This preparation is produced out of the following plant:

Specify the reaction to the ester-type drugs that is tolerated by the Ukrainian State Pharmacopoeia:

A pharmacist-analyst is measuring the quantity of an adrenaline tartrate substance by method of acid-base titration in nonaqueous solvents. Which indicator is to be used in this case according to the requirements of the Ukrainian State Pharmacopoeia?

Which of the following drugs a pharmacist-analys can quantify by ceriometry method?

A pharmacy makes wholesale purchases of health and hygiene products. An agent works under the contract with the manufacturer and makes deals at the manufacturer's cost. The agent may be entitled to exclusive distribution in some regions.What kind of agent is it?

Pharmaceutical market is in such a situation when there is only one company selling a certain product. Specify the competitive structure of the market:

A pharmaceutical company "Adonis" promotes its new products by means of advertisement that informs the customers about the product, highlights its advantages, typical features and properties. What kind of advertisment is it?

Liquid dosage forms are prepared with concentrated solutions of pharmacetical substances or under consideration of volume increase factor during substance dissolution when the following substance is used as a solvent:

A pharmacist-analyst is measuring the quantity of a drug by method of indirect bromatometry. Which of the following titrated solutions is to be used?

A pharmacist-analyst carries out quantitative analysis of procaine hydrochloride. Which of the following solutions is to be used? 12

A pharmacy analyst carries out purity test of the drug substance "Sodium thiosulfate" . Violet colour, that comes from reaction with sodium nitroprusside, indicates the presence of the following admixture:

An analytical laboratory received "Adrenalini tartras" substance for analysis. According to the requirements of the Ukrainian State Pharmacopoeia, quantitative analysis of this substance can be carried out by method of:

In Ukraine natural persons as small business entities are allowed to use the simplified tax system. What limit on the number of employees is established for such enterprises?

For the natural persons being small business subjects the simplified tax system is effective. But there is a limit of annual proceeds upon sale.What is the boundary amount of proceeds?

Simplified tax system implies replacement of several taxes by a single one. What limit on the number of employees is established for the legal persons to implement the simplified tax system?

A pharmacy as a legal person being the small enterprise plans to move to a simplified taxation system from 1 January. What is the limitation of the amount of sales revenue for such companies?

Fatty oil containing unsaturated fatty acids are used for atherosclerosis prevention. What herbal raw material contains such fatty oil?

An ampule production unit produces glucose solution. If the special sort of glucose "for injections" is not available, then the glucose should be separated from the following admixtures:

A phytochemical production unit produces biogenic stimulators out of different raw materials. Specify the biogenic stimulators of organo-mineral origin:

A pharmaceutical enterprise produces water solutions. The solution of the following substance is produced by method of chemical interaction and electrochemically:

Powders make up an important group among the extemporal medicinal preparations. Which of the following components can be incorporated into a powder without being preliminarily ground?

Upper airways diseases can be treated by means of herbal raw materials containing mucilages. The plant source of this compound class is:

The basic structure of steroid hormones is hydrocarbon skeleton cyclopentane perhydrophenanthrene. What natural compound is used for testosterone propionate production?

According to the requirements of the Ukrainian State Pharmacopoeia, a pharmacy analyst is determining calcium gluconate quantity by method of complexometric titration. What indicator is to be used?

Reaction with KI solution which is called "Golden Rain Reaction" helps to detect presence of the followingg toxic metal:

Presence of ethanol in a biological sample can be demonstrated by the following reaction:

Preparations containing cardiosteroids are produced out of the following herbal raw material:

A laboratory received some herbal raw material for analysis. It is a composition of ovoid-pointed leaves up to 25 cm long and 20 cm wide; the leaf base is cuneate, the leaf edge is emarginate, The cutting is long and cylindric. The leaf venation is pinnatisect; the midrib and the first-order veins project significantly on the inferior surface of the leaf. The superior leaf surface is dark green, the inferior surface is light green. The plant has a weak narcotic smell. The taste cannot be determined. The plant is poisonous! The described herbal raw material relates to the following plant:

It is necessary to prescribe non-steroid anti-inflammatory drug for patient with rheumatoid arthritis and concomitant duodenal ulcer. Which drug is the drug of choice in this case?

A pharmaceutist is preparing powders according to the following formulation: 14 Rp.: Scopolamini hydrobromidi 0,0003 Ephedrini hydrochlorodi 0,05 Sachari 0,15 M.f. pulvis D.t.d. № 10 S. 1 powder thrice a day. Calculate the mass of 1 powder providing that the trituration (1:100) is used:

Apharmaceutist prepared a suspension. It must contain the following amount of fluid in order to comply with Deriagin's rule:

The risk can arise from some forms of activity connected with production of goods and services, their selling, commodity-money and financial operations, commerce, implementation of socioeconomic and scientific-and-technical projects. This is the definition for the following concept:

The total of business transaction records of assets and liabilities in the accounting statement for a certain period is called:

Novocaine metabolism in the organism results in generation of p-aminobenzoic acid. What metabolic process underlies this conversion?

Tanning agents of silverweed roots and rhizomes are used as an astringent. What species of silverweed is pharmacopoeial?

Some domestic and foreign hepatoprotective activity preparation are made of holy thistle bearing. Purity of this material is determined by the content of:

Preparations made out of eleutherococcus roots and rhizomes are administered as a tonic and adaptogenic drug. If these preparations cannot be found in a pharmacy, they can be substituted by the analogous preparations made of the following raw material:

A pharmaceutical enterprise produces neogalenic preparations. Which preparation is produced by the use of Soxhlet circulation apparatus?

A pharmacy analyst identifies sodium hydrocarbonate.What indicator can confirm the presence of alkalescent medium reaction in the sodium hydrocarbonate solution?

A pharmacy got an order for powders containing ascorbic acid and sodium hydrocarbonate.What process takes place between the ingredients? 15

As main reagent in test for phosphates admixtures the Ukrainian State Pharmacopoeia recommends to use:

Salicylates are widely applied in medical practice as anti-inflammatory drugs. For quantitative analysis of salicylic acid the following method is applied:

As a pharmaceutist was serving a customer who ordered a nonprecription drug he realized that the patient didn't apprehend the verbal information. Name the communicative barriers that arise when words or symbols may have different meanings for the information sender and the recipient:

A pharmaceutist has applied for a job of a stockkeeper at a wholesale pharmaceutical enterprise. What trial period doesn't require agreement with the trade-union committee?

Marketingmanager at a pharmaceutical factory is planning its communication policy. Which component of the marketing communication systems has the highest value for one contact?

Incoming control is conducted in the course of wholesale and retail trade, such control is carried out during receipt of goods by visual inspection or analysis of drug. Incoming control is carried out by authorized person, which is assigned by:

When a pharmacy records goods as received, it normally specifies the amount of the markup intended for expenditure coverage and profit gaining. Give the definition for the markup:

A joint-stock company involved into production and selling of drug preparations has developed a structure for working with various consuming organizations. Such organizational structure is called:

Which of the following drug forms is produced in granules?

On the base of licorice root different drug dosage forms are produced, notably tablets, powders, syrups, teas. The only unused form is injection solution. Licorice roots exhibit haemolytic properties typical for the following active substances: 16

Benzylpenicillin sodium is not used per os, because this drug:

A pharmacy produces some injection solutions that have to be apyrogenic. Solution of the following substance can be depyrogenized by method of adsorption with activated carbon?

An accountant is recording business transactions of a pharmacy. Which transaction is to be entered on the credit side of the cash-account?