Крок 2 · Фармація, промислова фармація 2014 · Англійська

A sample of biological material contains mercury. Specify the method of mercury isolation:

A pharmaceutist has to prepare an oil emulsion with menthol. Specify the appropriate way of the active substance incorporation:

It is required to prepare a decoction of bearberry leaves. Specify the ratio of raw materials to the extractant if not indicated in the formulation:

A pharmaceutist prepared an injectable solution of novocaine. What stabilizer had been used?

A disabled veteran of the WW2 has been prescribed codeine powder. What is the maximum permissible amount of codeine that can be dispensed by the prescription?

Certain groups of drugs are subject to strict record keeping and storage in pharmacies. Specify a drug that relates to the group of narcotics:

Under the analytical normative documents, atropine sulfate should be titrated with hydrochloric acid solution in the anhydrous acetic acid medium in the presence of the following indicator:

Losartan as a part of treatment of arterial hypertension is contraindicated in case of:

Which of the following drugs is used for thrombolytic therapy in case of myocardial infarction?

At the end of the dug action drug addicts develop severe mental, neurological and somatic disorders. This complex of symptoms is called:

Patients with heart failure caused by persisting cardiac and coronary vessel dysfunction can be recommended preparations produced from the following herbal raw material:

Rutin exhibits P-vitamin activity. What medicinal plant is used as starting materials for the industrial production of rutin?

A patient came to a pharmacy to purchase cowberry leaves. Which of the available herbal raw materials can be offered as a substitute?

Pharmaceutical warehouse received a batch of herbal raw material of cinnamon rose. Under the State Pharmacopoeia, it is required to test this raw material for the following active substances:

Under the analytical normative documents, prior to direct bromatometric determination of arsenous acid anhydride the following substance should be added to the analyzed solution:

A pharmaceutical analyst of an analytical laboratory performs quantitative determination of silver nitrate by thiocyanatometry. What indicator is used in this case?

A pharmaceutical company produces concentrated extracts. Specify the concentration of ethanol in the extractant required for the production:

A factory workshop producing suspensions and emulsions is going to start manufacturing new drugs. What equipment can be used for the ultrasound processing of drugs?

The ointment workshop of a pharmaceutical plant launches production of a new ointment. Specify the manufacturing operation that ensures equal distribution of the drug substance in the base:

The aerosol workshop of a pharmaceutical plant uses various groups of propellants in the production. What propellants relate to the group of volatile organic solvents?

The phytochemical workshop of a pharmaceutical plant manufactures liquid extracts. How many volume parts of the liquid extract can be produced from one weight part of herbal raw material in compliamce with the State Pharmacopoeia?

An analytical laboratory received calcium gluconate for analysis. What method is used for its quantification?

A chemist of the production unit for ampouled medicinal preparations analyzes injectable solution of calcium chloride. According to the requirements, the analyzed solution should be colorless. To meet this requirement, the analyte should be compared to:

What drug is used as the specific antidote in case of intoxication with iron preparations?

Specify the type of capsules which are used for dispensing camphor powders:

A pharmacy received a formulation for an extemporaneously compounded medication. Specify the document that is used to set the price for such medication:

A pharmaceutist has prepared a suspension ointment. Specify the substance used for this type of ointments:

Ergot (Secale cornutum) is used as an uterotonic agent in obstetric practice and for the treatmet of cardiovascular diseases. The authenticity of the raw materials is proved by the content of:

Among the given principles of market segmentation select a principle that is used in the study of drug market most often:

Personnel records refer to the following type of documents:

A pharmacy received a formulation for eye drops containing 1% solution of pilocarpine hydrochloride. What substance should be used to ensure that the resultant solution is isotonic?

A pharmaceutist prepared 10 powders containing atropine sulfate in an amount of 0,00005 per dose. What trituration had been used?

Which of the following antihypertensive drugs has potassiumsparing effect?

Immunochemical test for detection of opiates in urine is carried out on polystyrene plates with the use of horseradish peroxidase as a label. This method is classified as:

When developing the system of marketing communications, a company should consider the characteristics of each tool used for market promotion of a drug. Which of the following characteristics is typical for advertising?

Quantitative determination of pyridine derivatives is performed by acidimetry in nonaqueous medium. What titrant is used for this purpose?

What antiprotozoal agent can be recommended to a female patient with trichomoniasis?

A patient has a history of chronic bronchitis. Recommend him an expectorant which can be purchased at a pharmacy to facilitate the expectoration of thick and viscous mucus:

What drug from the group of cardiac glycosides can be used as an alternative for strophanthine if it is not available at a pharmacy?

A pharmacy received the following formulation: Rp.: Xeroformii Picis Liquidae Betulae Olei Ricini 100,0 M.D.S. For wound anointing. Specify the dosage form:

What is the most common symptom of atropine intoxication?

In order to detect the presence of thiosulfate ions a pharmaceutical analyst added the excess reagent. The resulting reaction produced a white precipitate which was slowly turning yellow, then brown, and black. What solution was added?

Quantitative analysis of boric acid can be performed by alkalimetric titration in the presence of:

A customer came to a pharmacy and presented the prescription for Tramadol tablets. For how long such a prescription must be kept at a pharmacy?

A 6-year-old child with pneumonia had been administered an antibiotic. After treatment the child lost the hearing. What group of antibiotics might have caused this complication?

Suppositories are prepared by various methods such as rolling, pouring, pressing. What base is used in the pouring method?

Select the optimal antibacterial drug for the treatment of mycoplasma pneumonia:

Quantitative determination of pesticides in organic extracts after the isolation from the biological material can be done by various methods. What method of quantitative analysis of chlorophos is based on measuring the peak height parameter?

An analytical chemist of the quality control department of a pharmaceutical plant has to determine the average weight of glibenclami-de tablets. How many tablets should be tested for this purpose?

A pharmacy received 10 kg of hawthorn tincture which was packaged in 80 ml bottles. This operation should be recorded in the following document:

Employees of a pharmacy receive hourly rate wage and bonuses based on individual performance. What document is issued when calculating the payroll advance?

Help a medical student to select an adrenergic drug for the treatment of anaphylactic shock:

A 5-year-old child had accidentally drunk a bottle of eye drops. After 30 minutes the child developed shortness of breath, difficult swallowing, voice hoarseness, dilated pupils, hyperthermia. Which of the drugs might have induced the described manifestations?

A patient purchased peppermint leaves at a pharmacy. What recommendations on infusing this herbal raw material must be given by the pharmaceutist?

It is required to prepare 50 g of zinc ointment for a patient. What amount of zinc and vaseline must be weighed out by a pharmaceutist?

Sterilization methods applied for the preparation of drugs under aseptic conditions can be differentiated into physical, mechanical, and chemical ones. Specify the chemical method of sterilization:

A patient had been given an injection of 0,25% novocaine solution for the purpose of anaesthetization. Suddenly the patient developed red spots, intense sweating, tachycardia, bronchospasm, edema of nasal mucosa. What is the cause of this complication?

What is the mechanism of action of diclofenac sodium?

In order to identify deoxycorticosterone acetate a pharmaceutical analyst performed a steroid cycle reaction which produced cherry-red color and green fluorescence. What reagent was added?

When investigating the case of drug intoxication, the expert commission should find out, whether intoxication had been caused by opium or omnopon. For this purpose it is required to conduct an addititional test for:

Within an accounting period a pharmacy has been providing the population with the finished medications. What business transaction will have an effect on increasing inventory of the pharmacy?

Which of the following nonsteroid anti-inflammatory agents has the least harmful effect on the mucosa of the gastrointestinal tract?

A manufacturing enterprise plans to retail a new drug through the corporate network of pharmacies. What strategy of drug distribution will be used?

When preparing an ointment with castor oil and vaseline a pharmaceutist failed to obtain a homogeneous system. What is the most likely cause of incompatibility between these components?

In order to identify the toxic substance which was extracted from the acidic aqueous extract by an organic solvent, a toxicologist performed a murexide test which resulted in development of pink coloration. This indicates presence of the following substance in the sample:

Woolly foxglove is used as raw material for the production of the following drug:

A 60-year-old female patient has a history of essential hypertension (stage II), ischemic heart disease, bronchial asthma. After the correction of pharmacotherapy, a patient experienced an attack of bronchospasm, and an escalation of dyspnea. What drug had caused the complication?

A pharmaceutical analyst with a 6-year length of service is on a sick leave due to temporary disability. He is entitled to the sickness allowance in the amount of:

Sage leaves procured for the production of essential oil should be dried at a temperature of:

Which of the following antibiotics can be identified by means of the maltol formation test?

What is the main mechanism of action that underlies the bactericidal effect of penicillin on the coccal flora?

What is the drug of choice for the treatment of acute pyelonephritis in a pregnant woman in the I trimester?

What is the most suitable drug that can be recommended for the treatment of rhinitis accompanying an ARVI in a 7-month-old child?

What drug may cause the development of constipation in patients undergoing combined therapy for arterial hypertension?

In a pharmaceutical company both American and Japanese management styles are used. Select a characteristic feature of the Japanese management style:

Drug A is in the stage of market saturation. In order to push up intensive sales, management of the manufacturing company decided to use the following type of advertising:

A person got poisoned with alcohols. What alcohol derivatives are used for the analysis by the method of gas-liquid chromatography?

A pharmaceutical analyst identifies the substance of potassium acetate. What reagent confirms the presence of potassium cation in the analyte?

A pharmaceutical analyst tests potassium bromide for magnesium and alkaline earth metals impurity. What solution is used for this purpose?

A patient with a history of essential hypertension has been administered lisinopril. What is the mechani- sm of action of this drug?

A male patient has been administered an antiulcerant that blocks histamine receptors of the gastric mucosa. What drug is it?

Stimulation of beta-cells of the pancreas causes the hypoglycemic effect of the following drug:

A pharmaceutist prepared an ointment by the following formulation: Rp.: Tannini 0,2 Lanolini 3,0 Vaselini 10,0 M. utf. ung.

Business transactions are displayed in the accounts. The entry in the account ledger that is made to record the incoming of economic resources is called:

Within the matrix of Boston Consulting Group, a certain drug refers to a group of products called 'milking cash cows'. Specify the stage of the lifecycle of this drug:

An analytical laboratory has been commissioned to prove the presence of ethylenediamine in aminophylli-ne. Which of the following reagents makes it possible to detect ethylenedi-amine?

A patient has glaucoma. Recommend him a drug of the M-cholinomimetic group:

Advise an internship doctor on why iron preparations should not be administered together with antacids:

A female patient with pneumonia has been administered doxycycline hydrochloride. This drug relates to the following group of antibiotics:

A pharmacy received the goods according to the accompanying documentation. Who is responsible for keeping the record of medicines received by a business entity?

Under the SPh of Ukraine, one of the reactions for the detection of calcium cation presence in drugs is the reaction with:

A patient with cholelithiasis should be administered the following drug for the dissolution of cholesterol gallstones:

A patient with acute heart failure and cardiac glycoside intolerance was given an injection of dobutamine. What is the mechanism of its action?

Which of the methods to fill ampoules with injectable solutions makes it possible to protect capillaries from contamination with thick and viscous solutions?

When setting up a joint-stock company the founders discussed the issues of financial liability. What is the liability of the board members in a joint-stock company?

In order to verify the purity of the essential oil, some ethanol was added into the test tube with peppermint oil. The mixture became turbid. This means that the peppermint oil contains the following impurity:

5 % solution of methylcellulose is used as a stabilizer for preparing a suspension of the following drug substance:

An analytical chemist of the quality control department of a pharmaceutical plant can prove the presence of the cation in the test substance with a solution of potassium:

Magnesium peroxide identification is performed by the reaction of perchromic acid formation. What color is produced as a result of this reaction?

A forensic medicine laboratory received some biological material. It was to be tested for the presence of trichlorfon and dichlorvos. For their isolation a toxicologist infuses them with:

Pharmacies prepare injectable solutions. Which solution is prepared without any stabilizer?

Ammifurinum contains furocumari-nes. These biologically active substances are derived from:

Quality of ampouled injection solutions is tested as to various parameters. How many ampullae are to be checked for assessing the quality of sealing (hermeticity)?

A pharmacy compounds suspensions. What substance can be used for preparing a suspension without adding the stabilizer?

All employees are entitled to annual leave. What is the duration of the additional leave for pharmacy employees with non-standard working hours?

One of the packagings stored at the warehouse of finished products has a damaged label. It is known that the drug substance in this packaging relates to alkaloids. In course of group qualitative tests for alkaloids the drug substance reacted positively with murexide. Further identification of the drug substance should be limited to the following group of derivatives:

Industrial, labor and socioeconomic relations between the head of a pharmaceutical company and the employees are regulated by:

A pharmacy received the following formulation: Rp.: Dibazoli 0,05 Papaverini hydrochloridi 0,15 Sacchari 2,5 M. fiat pulv. Divide in partes aequales №10. Specify the weight of a single powder dose:

Xenobiotics are metabolized in the body. The main metabolite of the acetic acid is:

Under the SPhU, the pharmacopei-al preparation 'Aether anaestheti-cus'is not allowed to have peroxide impurity. What reagent should be used to detect peroxides?

Arrangement of drugs in the retail space of a pharmacy can be characterized as either strong or weak. What arrangement of drugs is regarded as weak?

When calculating the personal income tax, the tax social privilege is taken into account. Its rate depends on a certain statutory amount. Specify this amount:

Fatty oils containing unsaturated fatty acids are used for the prophylaxis of atherosclerosis. Specify the starting materials of herbal origin that contain fatty oil:

The phytochemical workshop of a pharmaceutical plant produces biogenic stimulators from different starting materials. Specify the biogenic stimulators of animal origin:

A pharmacy network received a batch of raw material without analysis protocol. It was identified as marshmallow root by the external charcteristics. The reaction with 5% alkali liquor was positive. This indi- cates the presence of:

A pharmaceutical analyst tests anhydrous glucose for purity according to the requirements of the SPhU. Inadmissible barium impurity can be detected by using the following acid:

The chemical name 1-benzoyl-5-ethyl-5-phenyl-barbituric acid stands for the following substance relating to barbiturates:

What herbal drug produced form alkaloid-containing raw materials can be recommended for neurasthenia, insomnia, menopausal disorders?

A pharmaceutist prepares 3000 mL of valerian root infusion for a hospital department. The given amount of extract should be infused in a water bath for:

A pharmaceutist has prepared a solution of menthol oil. Specify the dissolution temperature of the active substance:

Forensic toxicological analysis of a mineralizate revealed copper. For the initial detection of copper ions the following substance is used:

A patient has been found to have pesticide intoxication. Biochemical (cholinesterase) test was positive. What pesticide is likely to have caused the intoxication?

As a result of condensation of substituted malonic esters and urea the derivatives of the following substance are obtained:

Which of the following ophthalmic dosage forms is produced only industrially?

What medication should be used as an antidote to eliminate the respiratory depression caused by an overdose of a narcotic analgesic?

Fenofibrate relates to the following pharmacological group:

Which of the following vaginal dosage forms relate to the officinal formula, that is, are prepared in a pharmacy?

The glidants aerosil or magnesium stearate together with talc are added to the excipients in hard gelatin capsules in order to facilitate the following property:

A student has been prescribed a tonic. This may be the tincture of the following medicinal plant:

A 25-year-old female patient had been taking antibiotics for 7 days, the disease was complicated by the development of intestinal dysbiosis. This complication should be treated by the drugs of the following group:

Which group of adjuvants includes polyvinyl alcohol used under the SPhU?

Which of the following drugs should be used for prevention of bronchial asthma attacks?

A pharmaceutist has to prepare a medication by the following formulation: Rp.: Natrii hydrocarbonatis 2,0 Natrii benzoatis 1,5 Liquoris Ammonii anisatis 4 ml Aquae Mentae 100 ml M.D.S. 1 tablespoon 3 times a day. Specify the component that is added in the first place:

A pharmaceutist prepares an ointment under aseptic conditions on the sterile ointment base, namely the composition of vaseline and lanoline at a ratio 6:4. The drug substance is incorporated by suspension type. Such technique of ointment preparation is typical for the following substance:

Under the chemico-toxicological classification, toxic compounds are grouped according to the method of their isolation from the biological material. What compound can be isolated by steam distillation?

Toxic medicines are isolated from biological material at a certain pH level of the medium. What substance is extracted from acidic aqueous extracts?

What drug is indicated in case of taking an overdose of depolarizing muscle relaxants?

A 20-year-old female patient has been administered bicillin for rheumatic fever prophylaxis. Specify the frequency of bicillin-5 administration:

A 65-year-old male patient complains of nausea, vomiting, lethargy, seeing yellow spots in front of his eyes. The patient takes dai- ly 0,25 mg of digoxin, 100 mg of aspecardum, 50 mg of metoprolol. What pathological condition is this syndrome typical for?

Vincamine alkaloid reduces blood pressure, has a pronounced sedation effect, as well as hemostatic and anti-inflammatory effect. What herb is the source of this alkaloid?

The galenical preparations workshop produces belladonna tincture. Specify the required ratio for this dosage form:

Pharmaceutical plants produce ointments on various bases. Specify the ointment base having the most pronounced osmotic properties:

A patient with acute heart failure has been administered an adrenomimetic agent. What drug is it?

Oil liniments are produced with fatty oils used as a base. What kind of oil should be used by a pharmacist if it was not specified in the formulation?

A pharmacy received a formula for an alcohol solution of methylene blue with unspecified alcohol concentration. In this case, a pharmacutist must use ethyl alcohol of the following concentration:

Production unit for ampouled medicinal preparations produces procaine hydrochloride solution. This solution is stabilized by adding:

Recommend a drug for the treatment of tachyarrhythmia epi- sodes:

A 35-year-old female customer came to a pharmacy to purchase a medicine for the prevention of influenza. Which of the following drugs can be recommended?

Employees of a company can be instructed to go on a business trip by the orders of the company’s head. Specify the deadline for submission of an expense report after the employee’s return from the trip:

A pharmaceutical analyst analyzes a dosage form containing zinc sulfate. What reagent enables him to confirm the presence of the zinc cation in the analyte?

Lily of the valley is widely regarded as a cardiac stimulant and sedative. During the raw material procurement, the following plant may occur in the harvested crop:

A pharmaceutist prepares an infusion at a ratio of 1:30. What herbal raw material will be used?

A pharmaceutist has prepared vaginal suppositories. Specify the form of these suppositories:

Under the SPhU (appendix 2), leaves of ginkgo are standardized by the content of:

A clinical pharmaceutist invited to a medical conference made a report on the antiviral drug acyclovir. What is its mechanism of action?

What kind of marketing is provided in case of negative demand for goods and services, that is, in a situation when the demand is absent in a substantial part of the potential market?

Prescriptions for the controlled drugs dispensed under the reimbursement program (except for the narcotic and psychotropic preparations in substance) are issued on the following prescription form:

In case of the planned closure of a pharmacy for repair works, technical re-equipment or other works, a business entity is obliged to give a written notice to the Territorial State Inspectorate for Quality Control of Medicines in advance, but not later than:

Pharmacy №7 is engaged in both sales and production. What operations ARE NOT REGISTERED in the journal of laboratory and prepacking works?