Крок 2 · Фармація, промислова фармація 2015 · Англійська

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01

A pharmacist has prepared powders including extract of belladonna in the amount of 0,015 per dose. For ten doses he had to take the following amount of dry extract:

A 0,015 g
B 0,3 g
C 0,15 g
D 1,5 g
E 0,03 g
02

A pharmacy prepared a solution of macromolecular substance with limited swelling capacity.What solution was labelled "warm up before use"?

A Trypsin
B Gelatin
C Pepsin
D Methyl cellulose
E Pancreatin
03

A dispensing chemist can recommend a drug made from seeds of Aesculus hippocastanum to be taken as a veintonic and antithrombotic agent to treat venous congestion and veins dilatation of lower extremities. This drug is:

A Aescusan
B Ajmaline
C Marelin
D Flamin
E Phytolysin
04

Specify the normal spoilage ratio for toxic drugs, which should be taken into account by an inventory committee during stock-taking.

A 7,6%
B 1,9%
C 0,95%
D 3,0%
E No norm defined
05

A schedule of sanitation actions in pharmacies is regulated by the relevant normative documents. Cleaning day at a pharmacy must be scheduled for at least 1 time:

A In 5 days
B In a week
C In 10 days
D In 3 days
E In a month
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06

Specify which of the alkaloids given below will react positively to xanthines (murexide test):

A Ephedrine hydrochloride
B Atropine sulfate
C Papaverine hydrochloride
D Quinine sulfate
E Caffeine
07

Point out the type of labour division structure of management personnel:

A Administrative
B Upper
C Technical
D Horizontal
E Institutional
08

Losartan is contraindicated for treatment of arterial hypertension in case of:

A Pregnancy
B Hypokalemia
C Urine acid diathesis
D Hyperglycemia
E Hyperlipidemia
09

Which of the drugs listed below is used for thrombolytic therapy of myocardial infarction?

A Heparinum
B Streptokinase
C Рhеnуlіnum
D Acetylsalicylic acid
E Ticlopidine
10

An organisation has been founded to carry out several interconnected purposes. What type of organisation is it?

A Complex
B Private
C Small
D Budget
E Legal
11

Representatives of pharmaceutical companies have met to discuss urgent issues of their further work. This meeting belongs to the following type of organizational groups (teams):

A Role groups
B Managed groups
C Staff
D Formal groups
E Informal groups
12

Bellasthesin is a spasmolytic drug used in treatment of gastrointestinal diseases. What substance contained in Atropa Belladonna provides such an effect of the drug?

A Codeine
B Hyoscyamine
C Reserpine
D Caffeine
E Morphine
13

Stinging nettle (Urtica dioica) leaves are mostly used as a hemostatic in tinctures and liquid extract to treat lung, intestinal, and uterine hemorrhages. What bioactive substance provides hemostatic effect?

A Beta-carotene
B Digitoxin
C Rutin
D Vitamin K
E Reserpine
14

Vitali-Morin's reaction is used to identify tropane alkaloids in raw herbal material. Name the alkaloid that can be detected by this specific reaction.

A Platyphyllin
B Morphine
C Codeine
D Papaverine
E Scopolamine
15

Coumarins are natural compounds with their structure based on an benzo-alpha-pyrone skeleton. What reaction allows to detect this group of compounds?

A Iron (III) chloride reaction
B Wilson's reaction
C Cyanide test
D Lactone test
E Trim-Hill reagent
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16

The following raw herbal material was delivered for analysis: capitulum inflorescence is semicircular or conic in shape; no pedicles or only their remains; floral disk is naked, conic, hollow. Semiflorets are white, disk florets are yellow, involucres are yellow-green. The smell is specific, aromatic. The taste is bitter-spicy. What raw herbal material is it?

A Flores Chamomillae
B Flores Arnicae
C Flores Calendulae
D Flores Helichrysi arenarii
E Flores Millefolii
17

Standard raw herbal material of lily-of-the-valley is obtained by drying it at a temperature of 50-60°C in order to prevent the possibility of the following biochemical process:

A Oxidation of phenolic compounds
B Oxidation of resins
C Oxidation of terpenoids
D Volatilization of essential oils
E Enzymatic hydrolysis of cardiac glycosides
18

A patient with heart failure induced by long-term coronary vessel disorder can be administered a drug produced out of the following raw herbal material:

A Calendula flowers
B Berberis roots
C Aralia roots
D Hawthorn berries
E Ginseng roots
19

A patient came to a pharmacy and ordered cowberry leaves.Which of the available raw herbal materials can be offered as a substitute?

A Rizoma Calami
B Herba Achilleae millefolii
C Rizoma et radix Sanquisorbae officinalis
D Folium Uvae ursi
E Radix Taraxaci officinalis
20

Specify the pricing strategy of international market, which foresees establishing relatively low prices to work up the developed countries market.

A Price skimming strategy
B Premium pricing strategy
C Price leveling strategy
D Differential pricing strategy
E Penetration strategy
21

Point out the type of group poll that foresees a single survey of several experts to discuss a certain problem.

A Omnibus
B Delphi
C Focus group
D Panel
E Interview
22

Name the stage of drug life cycle that is characterized by maximal sales and profit, and reminder advertising.

A Market exit
B Introduction
C Decline
D Maturity and saturation
E Growth
23

The following fruit was received for analysis: succulent drupes circular or elongated-ellipsoid in shape, 4-12 mm in length. The colour of fruit varies from yellow to dark orange. The smell is faint. The taste is sour-sweet. What plant is it?

A Aronia melanocarpa
B Hippophae rhamnoides
C Ammi majus
D Vaccinium myrtillus
E Coriandrum sativum
24

Cumulating drugs - Digitoxin and Соrdіgіtum - are used to treat chronic cardiac insufficiency. What plant is used as a raw material to produce them?

A Erysimum canescens
B Digitalis purpurea
C Adonis vernalis
D Convallaria majalis
E Strophanthus kombe
25

Business trip can be assigned to employees only with their consent, if these employees are:

A Women with children from 3 to 14 years of age
B Women with children less than 1 year old
C Women with two children
D Any employee
E Women with children from 1 to 3 years of age
26

An analytical chemist working at a pharmacy identifies oxacillin sodium salt. As a reagent he uses hydroxylamine hydrochloride solution in presence of sodium hydroxide solution and copper nitrate solution. What structural fragment of the drug molecule can be detected by these reagents?

A Beta-lactam cycle
B Furan cycle
C Thiazolidine cycle
D Isoxazole cycle
E Thiadiazole cycle
27

A pharmaceutical enterprise that has achieved high sales rates and customers' recognition will reach the highest profit at the following stage of the product life cycle:

A Maturity
B Decrease
C Development
D Market penetration
E Growth
28

A factrory workshop producing suspensions and emulsions is developing manufacture of new drugs. What mechanisms can be used for ultrasound production of drugs?

A Disintegrator, liquid whistle
B Rotor-pulsation apparatus, dismembrator
C Liquid whistle, magnetostrictive source
D Centrifugal mixer with rotating housing
E Dismembrator, electrical impulse plasmolyzer
29

A pharmaceutic factory workshop producing ointments can use the following equipment at the packing stage:

A Eccentric machines
B Disc machines
C Rotary machines
D Rezepin automatic machine
E Screw and piston dosing machines
30

What preparation is the specific antidote in case of intoxication with iron preparations?

A Penicillamine
B Atropinum
C Bemegridum
D Protamine sulfate
E Deferoxamium
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31

A pharmacist has a labour dispute with the pharmacy administration about rescheduling his annual vacation leave. The employee can appeal against the decision of the pharmacy administration to the following body:

A Commercial court
B Trade union committee
C Highest management bodies of pharmaceutical service at the regional level
D MoH of Ukraine
E Labour disputes commission (LDC)
32

A pharmacist has prepared solution of ethacrydine lactate. Name the peculiarity of this substance dissolution.

A Dissolving in cold water
B Dissolving in freshly distilled water
C Grinding in a mortar with water
D Dissolving in potassium iodide solution
E Dissolving in hot water
33

A pharmacy received a prescription for an extemporaneous compounded drug. Specify the document that is used to set the price for such drug:

A Retail price list for drugs
B Certificate of quality
C Inventory report
D Certificate of analysis
E Cash receipt voucher
34

Medications Passit and Novopassit are used as tranquilizing, sedative and mild soporific agents. These medications are produced from the following grass:

A Elecampane
B Purple passionflower
C Three-lobe beggarticks
D Garden sage
E Lesser periwinkle
35

Thymol is the main component of Thymus serpyllum essential oil. What is the time of harvesting for this raw herbal material?

A Beginning of vegetation
B In autumn after above-ground part of a plant dies-off
C Peak florescence period
D During fruiting
E During peak of sap movement
36

An essential oil is a component of such compound drugs as: Inhalypt, Corvalol, Pinosol, Corvaldin, tooth drops. What raw herbal material is a source of this essential oil?

A Folia Absinthii
B Folia Betulae
C Folia Menthae piperitae
D Folia Urticae
E Folia Agavae
37

When developing the system of marketing communications, a company should consider the characteristics of each market promotion means applied for a drug. Which of the following characteristics is typical for advertising?

A Depersonalization (non-personal communication)
B Two-way communication
C There is no correct answer
D All answers are correct
E Non-mass communication
38

A pharmaceutical factory produces suspensions and emulsions. Specify the equipment that is used for dispersion and mixing in liquid medium:

A Oscillating mixers
B Drum mixers
C Anchor mixers
D Rotor-pulsation apparatus, colloid mixers
E Gate mixers
39

What reagent is used to detect calcium admixture in medicinal substances?

A Barium chloride
B Potassium carbonate
C Ammonium oxalate
D Silver nitrate
E Sodium sulfate
40

A pharmacy received a prescription for vaseline-lanoline based eye ointment.What proportion of vaseline to lanoline should be chosen by a pharmacist to make the ointment base?

A 8:2
B 9:1
C 1:1
D 7:3
E 5:1
41

Pharmacist has made an althaea root tincture.What proportion of raw herbal material to extractant was chosen by the pharmacist to make this tincture?

A 1:20
B 1:100
C 1:10
D 1:30
E 1:400
42

Collective labour agreement is concluded by a trade union committee with an enterprise owner on behalf of the workforce. Any collective agreement is worked out in written form. Which article of the Labor Code regulates the duration of the collective agreement?

A 38
B 17
C 40
D 41
E 36
43

To stimulate sales a pharmaceutical wholesale company grants its customers a discount according to the social contract and on condition of their loyalty. Specify the type of discount:

A Bonus
B Discounts for quantity of purchased goods
C -
D Seasonal
E Dealer
44

One of the quality indicators for finished ampoules is lack of residual stress in the glass. Which operation at the "Preparation of ampoules to be filled"stage eliminates this imperfection?

A Ampoule drying
B Ampoule washing
C Ampoule annealing
D Ampoule sterilization
E Capillary opening
45

Companies producing injectable dosage forms apply different methods of ampoule sealing. Sealing against a jet of inert gases (nitrogen, argon, carbon dioxide) is suitable for the following injection solutions:

A Easily oxidable
B Thermostable
C Viscous
D Photosensitive
E Hydrolytically unstable
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46

A pharmacist prepares a solution for injections that must be stabilized with 0,1M of hydrochloric acid solution. What solution is to be prepared?

A Novocaine
B Hexamethylenetetramine
C Potassium chloride
D Calcium chloride
E Sodium benzoate
47

Paracetamol substance has been sent for analysis. Reaction with the solution of iron (III) chloride resulted in blue-purple colouring. This indicates the presence of:

A Phenolic hydroxyl
B Keto group
C Alcoholic hydroxyl
D Ester group
E Aldehyde group
48

Production of tablets requires stage-to-stage quality control. What devices are used to determine the particle size distribution (fraction) of granules?

A Microscope
B Friabilators
C Standard set of sieves
D Laboratory identifiers
E Various vibrosieves
49

According to the State Pharmacopoeia of Ukraine, in order to test a substance for the highest level of magnesium impurities an analytical chemist must use the following solution:

A Benzaldehyde
B Pyridine
C Hydroxyquinoline
D Formaldehyde
E Resorcin
50

Preparations of sorrel roots can have both laxative and astringent effect. Such an effect results from the presence of the following biologically active substances:

A Anthracene derivatives and tannins
B Flavonoids and essential oils
C Iridoids and vitamins
D Essential and fatty oils
E Coumarins and phenol glycosides
51

Theory of management currently specifies the four most important approaches to the management. Select the approach that IS NOT applied in the management theory:

A Process approach
B Systemic
C Different schools dedication approach
D Situational
E Structured
52

A pharmacist worked on a holiday and his work hours were within the norm for the current month. The employee would be entitled to be paid:

A Fixed salary + double daily rate
B There would be no extra pay
C According to the standard procedure as for a normal working day
D Single piecework rate
E Fixed salary + one daily rate
53

A pharmacy has a license for selling narcotic drugs. The warrant for the receipt of these drugs from the pharmacy warehouse is valid for:

A No longer than 5 calendar days from the date of issue
B No longer than 10 calendar days from the date of issue
C No longer than 1 year from the date of issue
D No longer than 3 months from the date of issue
E No longer than 1 calendar days from the date of issue
54

Which of the pharmacy departments is responsible for checking the quantity and quality of received goods, their storage and dispensing to other departments?

A Department of finished dosage forms
B Compounding and production department
C Department of curative cosmetics
D Department of over-the-counter drugs
E Inventory department
55

Chloride of lime is identified by calcium cations after boiling with acetic acid in order to eliminate active chlorine.What reagent is used?

A Ammonium molybdate
B Magnesium sulfate
C Sodium nitrite
D Potassium chloride
E Ammonium oxalate
56

A set of values, traditions, behavioral norms and views inherent to an organisation characterize its following feature:

A Sapitalization level
B Profitability
C Culture
D Self-development capability
E Success
57

Products differentiation (advantages) pursued by a pharmaceutical company with the aim to surpass its competitors in satisfying customers's demands is called:

A Concentration strategy
B Product leadership
C Benchmarking
D Porter's generic strategies model
E Penetration strategy
58

A patient bought mint leaves at a pharmacy. What recommendations regarding infusion of this raw herbal material must be given by a pharmacist?

A The extract is to be immediately filtered after infusing
B The infusion is to be prepared on open fire
C The infusion is to be prepared in a tightly closed vessel
D The infusion is to be prepared at room temperature
E The extract is to be artificially cooled 15 minutes after infusing
59

A patient has been administered a solution containing boric acid and camphor. What solvent should his doctor prescribe to prevent physical incompatibility?

A Ethyl alcohol 40%
B Ethyl alcohol 70%
C Sunflower oil
D Glycerol
E Purified water
60

A patient has chronic pancreatitis with apparent presentations of pancreatic exocrine hypofunction. Which of the following drugs would be the most advisable in this case?

A Drotaverine
B Dе-Nоl
C Оmерrаzоlе
D Раnсrеаtіnum
E Acidin pepsinum
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61

A manufacturing company initiates changes to the package insert of a drug aimed at limitation of its use. What type of marketing is used by the company in this case?

A Synchromarketing
B Conversion
C Remarketing
D Counteractive
E Stimulating
62

An ampoule workshop produces injection solutions. What filters are used for sterile filtering of injection solutions?

A Membrane and depth filters
B Druck (pressure) filter
C Filter designed at the Kharkiv Chemico-Pharmaceutical Research Institute
D Nutsche (vacuum) filter
E Pressure leaf filter
63

Injection solutions of weak acids and strong bases must be stabilized. What stabilizers are used for such solutions?

A Butyloxytoluene
B Ascorbic acid
C 0,1 М sodium hydroxide solution
D 0,1 М hydrochloric acid solution
E Sodium edetate (Disodium EDTA, Trilon B)
64

A pharmacy makes infusion solutions. Specify the solution that restores water-salt metabolism.

A Polyglucinum
B Ringer-Locke's solution
C Neohaemodesum
D Dextran
E Hydrolysine
65

Prior to making a sodium chloride isotonic solution a pharmacist baked the powder in a dry heat box. What substances are removed by this operation?

A Chlorides
B Redox substances
C Sulfates
D Pyrogenic substances
E Moisture
66

Yellow gentian contains bitter glycosides. Raw material of this plant is recommended for production of drugs with the following effect:

A Stimulates appetite
B Diuretic
C Hepatoprotective
D Venotonic
E Tonic
67

A pharmacy received a prescription for tincture. What raw herbal material can be used to make this dosage form?

A Valerian rootstock
B Arrow-wood bark
C Oak bark
D Buckthorn bark
E Rhubarb roots
68

A retail pharmacy has been purchasing goods within an accounting period. What changes to the balance will result from these business transactions?

A Increase in assets and liabilities
B Decrease in assets and liabilities
C -
D Changes will be caused to the assets only
E Changes will be caused to the liabilities only
69

Which of the following nonsteroid anti-inflammatory agents has the least harmful effect on mucosa of gastrointestinal tract?

A Diclofenac
B Acetylsalicylic acid
C Piroxicam
D Nimesulide
E Indomethacin
70

When doing calculations to determine the limit of the cash balance, an accountant must specify the actual amount of cash receipts. What time period should be taken into account?

A 10 days prior to calculation
B 1 year prior to calculation
C Three months prior to calculation
D Six months prior to calculation
E 7 days prior to calculation
71

A doctor wrote a prescription for the tincture of digitalis with hydrochloric acid. What is the reason for their incompatibility?

A Change in colour
B Precipitation
C Gassing
D Hydrolysis (with no visible change)
E Change in odour
72

During the analysis of diethyl ether (Aether medicinales) you can determine presence of aldehydes as a specific admixture. Which of the following reagents can be used for determining presence of aldehyde admixtures?

A Potassium sulfate
B Acetic acid
C Iron (III) chloride
D Potassium tetraiodomercurate alkaline
E Phenolphtalein
73

A pharmacist prepared a drug according to the following prescription: Rp.: Streptocidi Dermatoli ana 1,0 Lanolini Vaselini ana 5,0 M.D.S.: Apply to the affected skin. Specify the type of disperse system:

A Solution ointment
B Extraction ointment
C Combined ointment
D Suspension ointment
E Hydrophilic ointment
74

Efficiency of aerosol therapy is to considerable extent determined by the size of disperse particles. What factor determines the size of aerosol particles during dispersion of an aerosol?

A Fractional composition, containers filling method
B System homogeneity, dispersion velocity
C Reduction range, container quantity
D Percentage of phase, filling temperature
E Exit port diameter, propellent vapour pressure
75

A pharmacistmakes powders with papaverine hydrochloride. What hand scales should be used for weighing out 0,05 g of substance?

A BP 1,0 (balance beam scale, capacity 1,0)
B BP 2,0 (balance beam scale, capacity 2,0)
C BP 20,0 (balance beam scale, capacity 20,0)
D BP 5,0 (balance beam scale, capacity 5,0)
E BP 10,0 (balance beam scale, capacity 10,0)
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76

Raw herbal material with the following features was delivered to a laboratory for analysis: fine flat glossy egg-shaped seeds (one end is sharp, other - rounded). Seed surface is smooth, vary in colour from pale yellow to brown, has pale yellow raphe. No smell is detected. The taste is slimy and oily. Name this raw herbal material.

A Plantago psyllium seeds
B Strophanthus seeds
C Peanut seeds
D Flax seeds
E Pumpkin seeds
77

Activated carbon is used in production of injection solutions for:

A Buffer system creation
B Chemical resistance of ampoule's glass increasing
C Ampoules residual stress relaxation
D Purification
E Antioxidant properties increasing
78

Intoxication cases were observed during harvesting raw herbalmaterial containing potent and toxic substances.What raw herbal material SHOULD NOT be harvested by underage and pregnant?

A Blueberries
B Celandine grass
C Buckthorn bark
D Valerian rootstock
E Walnut leaves
79

Which of the listed antibacterial drugs should NOT be administered to a patient with diabetes mellitus type II being treated with glibenclamid?

A Gentamycinum
B Midecamycin
C Doxycycline
D Co-trimoxazolum
E Benzylpenicillinum
80

Plantaglucide is used to treat peptic ulcer disease of stomach and duodenum with normal acidity and hypoacidity. This drug is obtained from the following plant:

A Plantago media
B Plantago major
C Plantago stepposa
D Plantago psyllium
E Plantago lanceolata
81

Drug A is in the stage of market saturation. In order to push up intensive sales, management of the manufacturing company decided to use the following type of advertising:

A Sales promotion
B Aggressive
C Personal sales
D Public relations
E Informational
82

Which of the penicillins given below can be identified by reaction with ninhydrin?

A Carbenicillin
B Oxacillin
C Phenoxymethylpenicillin (penicillin V)
D Benzylpenicillin (penicillin G)
E Ampicillin
83

Preparations of common valerian are used in medical practice as sedative drugs. The main feature that allows to distinguish valerian from the admixtures is:

A No specific odor
B Specific taste
C Stems remains
D Specific color of raw materials
E Specific odor
84

An analytical chemist determines the admixture of sulphates in boric acid. What is the main reagent to be added?

A Sodium sulphide
B Silver nitrate
C Barium chloride
D Potassium ferrocyanide
E Ammonium oxalate
85

A pharmaceutical company conducted an age-specific segment analysis of the regional antihistamine market. It revealed the lack of antihistamines for children. The company will consider this segment as:

A Amarket share
B A segment requiring further research
C An unattractive segment
D A market door
E Amarket niche
86

Calcium cations present in drugs can be detected with the following solution:

A Sodium nitrite
B Sodium chloride
C Potassium permanganate
D Silver nitrate
E Ammonium oxalate
87

What stage is the last in making injection solutions?

A Filtering
B Labeling
C Quantitative control
D Sterilization
E Qualitative control
88

An analyst of the State Inspectorate for Quality Control identifies "Sulfametoxazol"by adding solutions of hydrochloric acid, sodium nitrite and beta-naphthol to the preparation. As a result intense red colouring is observed. What functional group is identified by this reaction?

A Aldehyde group
B Primary aromatic amino group
C Carboxyl group
D Secondary aromatic amino group
E Sulpho group
89

Pharmaceutical analyst working at the laboratory of the State Inspectorate for Quality Control of Medicines identifies the drug substance "Glucose anhydrous"with copper-tartrate solution (Fehling's reagent). What is the colour of produced precipitate?

A Black
B Purple
C Blue
D White
E Red
90

Specify the indicator which measures total contribution of various solutes to osmotic pressure of a solution:

A Apyrogenicity
B Isohydricity
C Isoviscosity
D Isotonicity
E Osmolality
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91

When setting up a joint-stock company the founders discussed the issues of financial liability. What is the liability of the shareholders in a joint-stock company?

A Limited to the value of their shares
B Unlimited and solidary
C Limited to the contributions to the statutory fund and their property
D Limited to the amount of deposits
E Limited to the double amount of deposits
92

A pharmacy opens a bank account to store funds and conduct ongoing business transactions. What kind of account should be opened?

A Provisional
B Investment
C Deposit
D Current
E Letter of credit
93

Specify the reaction to identify ester-type drugs, which is required by the regulations of the State Pharmacopoeia of Ukraine:

A Formation of iron hydroxamates
B Formation of 3-bromphenol
C Formation of azo dye
D Formation of indophenol
E Formation of tayleohin
94

Streptocide, sulfacyl sodium, norsulfazole or sulfadimezinum can be identified by the reaction forming the following substance:

A Azo dye
B Tayleohin
C Fluorescein
D Murexide
E Iodoform
95

A pharmacy makes bulk purchases of health and hygiene products. An agent works under a contract with a manufacturer and operates on his account. The agent may be given exclusive right to sell goods in certain regions. Specify this agent:

A Consignee
B Dealer
C Commission agent
D Wholesale agent
E Broker
96

A pharmaceutical company has made a decision to expand its activities. The process of the company's activity expansion by penetration into new fields of the branch is called:

A Segmentation
B Integration
C Centralization
D Conglomeration
E Diversification
97

To identify a drug an analytical chemist of the State Inspectorate for Quality Control performs a lignin test. Specify this drug:

A Streptotcid
B Analgin
C Ascorbic acid
D Methionine
E Cortisone acetate
98

The main active components of hawthorn berries are flavonoids. What is their pharmacological effect?

A Tonic and antispasmodic
B Diuretic and styptic
C Hypotensive and sedative
D Antispasmodic and antiinflammatory
E Laxative and sedative
99

An analytical laboratory received "Adrenalini tartras"substance for analysis. According to the requirements of the Ukrainian State Pharmacopoeia, quantitative analysis of this substance can be carried out by the method of:

A Bromatometry
B Acidimetry in aqueous medium
C Acidimetry in non-aqueous medium
D Iodometry
E Nitritometry
100

Quality of dried extracts is assessed according to several criteria. Specify the highest acceptable amount of moisture in dried extracts according to the State Pharmacopoeia of Ukraine.

A 20%
B 75%
C 25%
D 95%
E 5%
101

What is the function of anhydrous lanolin in the suppository mass used for suppositories made by hand rolling?

A Solvent
B Preservative
C Plasticizer
D Emollient
E Solubilizer
102

The basic structure of steroid hormones is hydrocarbon skeleton - cyclopentane perhydrophenanthrene. What natural compound is used for testosterone propionate production?

A Cholesterol
B Anthracene
C Indole
D Naphthalene
E Phenanthrene
103

A dispensing chemist was addressed by a patient with the prescription of acetylsalicylic acid as antiaggregant. What daily dosage in grams should be recommended for him to take on a regular basis?

A 0,5-1,0
B Over 4,0
C 2,0-3,0
D 0,1—0,3
E 1,0-2,0
104

A patient with arterial hypertension and chronic bronchitis suddenly developed dry cough and dyspnea; his body temperature remained without changes. It is known that the patient takes captopril. This phenomenon can be explained by increased synthesis of:

A Natriuretic peptide
B Bradykinin
C Aldosterone
D Angiotensin I
E Renin
105

Preparations containing cardiosteroids are produced out of the following raw herbal material:

A Radix Taraxaci
B Folia Ficusi Caricae
C Cortex Quercus
D Herba Convallariae
E Folia Sennae
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106

A pharmacist has prepared a solution of menthol oil. Specify the dissolution temperature of the active substance:

A 30-40oC
B 60-70oC
C 20-30oC
D 40-50oC
E 70-80oC
107

The risk can arise from some forms of activity connected with production of goods and services, their selling, commodity-money and financial operations, commerce, implementation of socioeconomic and scientific-and-technical projects. This is the definition of the following concept:

A Financial loss
B Loss of property
C Loss of time
D Labour loss
E Business risk
108

Admixtures can be accidentally included in raw herbal material in the process of harvesting, drying and primary processing. Mineral admixtures include:

A Sand, earth, stones
B Other similar plants
C Droppings of birds and rodents
D Other organs of the same plant
E Metal objects
109

A pharmaceutical enterprise produces neogalenic preparations. What preparation is produced by the Soxhlet circulation apparatus?

A Corglyconum
B Lantosidum
C Аdоnіsіdum
D Сеlаnіdum
E Digoxin
110

The common method for quantitative determination of drugs from the group of alkali metal halogenides is:

A Argentometry
B Chelatometry
C Nitritometry
D Permanganatometry
E Alkalimetry
111

When a pharmacist was serving a customer who ordered a nonprecription drug he realized that the patient did not apprehend verbal information. Name the communicative barriers that arise when words or symbols may have different meanings for information sender and recipient:

A Neglect of facts
B Nonverbal barriers
C Failure to understand the importance of information
D Semantic barriers
E Stereotype mentation
112

A pharmacist should make 200 ml of 3%sodium bicarbonate solution for injections.What are the specifics of making this solution?

A Vial should be filled to 2/3 of its volume; sterilization at 120 0C for 12 minutes
B Dissolve by heating; sterilization at 120 0C for 12 minutes
C No sterilization
D Use water free of redox substances
E Use stabilizing agent
113

What technology should be chosen by a pharmacist to make a liquid dosage form, if it contains calcium gluconate?

A Dissolve it in hot solvent or heat it up to full dissolution
B Dissolve in water free of redox subsatances
C Add equal amount of sodium chloride
D Dissolve in alkaline medium
E First grind it to powder when it is dry or with small amount of solvent added
114

Concentrated solutions CANNOT be used in mixturemaking if:

A Mixture contains syrups
B Purified water is solvent
C Mixture contains a potent agent
D Mixture contains tinctures
E Aromatic water is solvent
115

Tyndallization is used at a pharmaceutical factory as one of sterilization methods for thermolabile substances.What is the essence of this method?

A Autoclaving at 119-121 0C with pressure at 1,0-1,1 atm
B Sterilization with high-frequency and microwave frequency current
C Triple heating of solution to 40-60 0C with 24-hour-long intervals in between for thermostating
D Sterilization with flowing steam at 100 0C
E Sterilization with dry heat at 180-200 0C for a lengthy period of time
116

What final document is used for preparation of a report on the discrepancies revealed in the course of inventory taking at a pharmacy?

A Checklist
B Invoice
C Act on inventory results
D Commercial report
E Inventory item description
117

Select the reductant required for determination of arsenic impurity in drugs (method 2):

A Potassium iodide solution
B Sodium hypophosphite
C Sodium hydroxide solution
D Sodium sulfite solution
E Hydrochloric acid solution
118

Choose the substance that is a tropane-derived alkaloid:

A Pilocarpine
B Caffeine
C Platyphyllin
D Strychnine
E Cocaine
119

A pharmacy produces some injection solutions that have to be apyrogenic. Solution of the following substance can be depyrogenized by the method of adsorption with activated carbon:

A Papaverine hydrochloride
B Glucose
C Platyphyllini hydrotartras
D Scopolamine hydrobromide
E Atropine sulfate
120

A pharmacy received a prescription for external use powder containing a substance difficult to pulverize. What liquid can be used by a pharmacist to disperse this substance?

A Purified water
B Dimethyl sulfoxide
C Ethyl alcohol
D Water for injections
E Isopropyl alcohol
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121

Specify the amount of raw herbal material necessary to make a dosage form according to the following prescription: Take 200 ml of motherwort herb solution. Dispense. Prescribed dosage is 1 tablespoon 3 times a day.

A 10,0
B 4,0
C 20,0
D 1,0
E 5,0
122

Which of the liquids given below should be measured by volume in making liquid dosage forms?

A 20% solution of sodium bromide
B Diethyl ether
C Glycerine
D Vaseline oil
E Eucalyptus oil
123

A pharmacy received prescriptions for compound powders containing colouring agent. Which of powder components given below is a colouring agent?

A Ethacridine lactate (Rivanol)
B Sulfanilamide
C Camphor
D Silver proteinate (Protargol)
E Bismuth nitrate
124

A teenager with hyporexia has been recommended to drink medicinal herbal tea of the following composition: Herba Absinthii, Herba Millefolii. Specify the characteristic microscopic features of Artemisia absinthium, which indicate its presence in the herbmixture:

A T-shaped hairs along the leaf edge
B Retor-shaped hairs
C Branched and capitate hairs
D Simple and capitate hairs
E Branched, simple and ciliated hairs
125

A laboratory received some raw herbal material for analysis. The plant had flowerheads up to 4 cm in diameter, marginal flowers were agamic, blue, funnel-shaped; the inner flowers were bisexual, purple, tubular.What plant has these features?

A Viola tricolor
B Centaurea cyanus
C Scutellaria baicalensis
D Solidago virgaurea
E Polygonum persicaria
126

Quantitative content of theophylline can be determined by alkalimetric titration of nitric acid that is quantitatively exudated as the result of the following theophylline salt production:

A Silver
B Ammonium
C Potassium
D Lithium
E Sodium
127

Complexometric titration (chelatometry) allows to determine quantitative content of:

A Potassium iodide
B Potassium chloride
C Sodium thiosulfate
D Calcium lactate
E Sodium citrate
128

A patient suffers from peptic ulcer disease. In the process of combined pharmacotherapy his feces became black. Name the drug that could be the cause of this.

A Omeprazole
B Actovegin
C Metronidazole
D Ranitidine
E Bismuth subcitrate
129

A patient suffering from bronchial asthma was diagnosed with essential hypertension.What antihypertensive drug is contraindicated for this patient?

A Amlodipine
B Captopril
C Propranolol
D Verapamil
E Hypothiazid (Hydrochlorothiazide)
130

A man with a long history of chronic hepatitis has been diagnosed with pneumonia. Which of the following antibacterial drugs can be applied in this clinical situation?

A Biseptol
B Vancomycin
C Rifampicin
D Tetracycline
E Amoxicillin
131

A 57-year-old patient is diagnosed with rheumatoid arthritis. Anamnesis states peptic ulcer disease. What nonsteroidal anti-inflammatory drug can be recommended for this patient?

A Celecoxib
B Indometacin
C Mefenamic acid
D Aspirin
E Diclofenac
132

A patient suffering from moderately severe pneumonia was prescribed ceftriaxonum once a day. Prescription of ceftriaxonum once a day is due to the fact that the drug:

A Is slowly eliminated from the body
B Accumulates in the lungs
C Is pluripotential
D Has bactericidal effect
E Is poorly absorbed from the injection site
133

According to the requirements of the State Pharmacopoeia of Ukraine (Addendum 1) a pharmacy analyst has to apply the following method for quantitative analysis of potassium iodide:

A Acidimetry
B Iodatometry
C Complexonometry
D Alkalimetry
E Nitritometry
134

A pharmacy received a prescription for an alcohol solution of methylene blue with unspecified alcohol concentration. In this case a pharmacist must use ethyl alcohol of the following concentration:

A 60%
B 70%
C 40%
D 96%
E 90%
135

Ampoule workshop of a pharmaceutical factory produces procaine hydrochloride solution. This solution is stabilized by adding:

A 1,5 g of amino-propylene glycol
B 20,0 of sodium hydrogen carbonate
C 0,1 mol/l of sodium hydrogen carbonate solution
D 0,1 mol/l of hydrochloric acid solution
E 0,1 mol/l of sodium hydroxide solution
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136

What stage of drug life cycle is characterized by quick increase of its sales amount and customers' recognition?

A Decline
B Saturation
C Introduction
D Growth
E Maturity
137

Prescriptions for controlled drugs dispensed under the reimbursement program (except for narcotic and psychotropic preparations in substance) are issued on the following prescription form:

A №1 in duplicate
B №3 in duplicate
C №3, single copy
D №1 and №3
E №1, single copy
138

Log books of stock-taking records are kept in a pharmacy for:

A 7 years
B 2 years
C 3 years
D 5 years
E 10 years
139

What principle of goods and expenses accounting requires presenting results of business transactions within the same reporting period when the transaction occurs?

A Accrual
B Periodicity
C Continuity
D Autonomy
E Matching
140

What method is recommended by the State Pharmacopoeia of Ukraine for quantitative determination of potassium chloride substance that is used in treatment of hypokalemia?

A Cerimetry
B Polarimetry
C Argentometry
D Bromatometry
E Iodometry
141

Who is responsible for reception of goods and medical products with simultaneous incoming quality control?

A Analyst
B Pharmacist
C Head of pharmacy
D Supplier pharmacist
E Authorized representative
142

A pharmaceutical factory produces herbal juice out of fresh raw herbal material.What operation should be performed at the stage of juice purification?

A Heating followed by quick cooling
B Crystallization
C Sedimentation
D Adsorption
E Filtration
143

Cash transactions at a pharmacy are recorded in the cashbook.Which of the following cash transactions IS NOT a receipt transaction?

A Issuing cash to be accounted for
B Recognizing accrued salaries and advance payable
C Return of unused disbursement funds
D Recognizing cash receipts from sales at a pharmacy
E Recognizing cash receipts from sales at pharmacy outlets and kiosks
144

.Which of the following diuretics SHOULD NOT be administered to patients with impaired hearing?

A Clopamide
B Indapamide
C Spironolactone
D Chlorthalidone
E Furosemide
145

A patient, who has been taking acetylsalicylic acid, has developed hemorrhages of mucous membranes. This phenomenon is associated with:

A Decreased absorption in gastrointestinal tract
B Increased absorption in gastrointestinal tract
C Disorder of protein binding
D Changed volume of distribution
E Inhibition of prothrombin synthesis
146

Simultaneous use of paracetamol and acetylcysteine causes:

A Increase of mucolytic action of acetylcysteine
B Increase of paracetamol nephrotoxicity
C Reduction of anti-inflammatory action of paracetamol
D Inhibition of paracetamol absorption
E Reduction of paracetamol hepatotoxicity
147

Simultaneous use of gentamicin and acyclovir tablets increases the risk of:

A Allergic reactions
B Neurotoxicity
C Cardiotoxicity
D Hepatotoxicity
E Nephrotoxicity
148

Simultaneous use of doxycycline hydrochloride and oral contraceptive causes:

A -
B Increase of antibacterial effect of doxycycline
C Reduction of oral contraceptives effectiveness
D Reduction of antibacterial effect of doxycycline
E Increase of oral contraceptives effectiveness
149

In case of simultaneous use of metronidazole and oral anticoagulants derived from coumarin patients must be warned about:

A Higher neurotoxicity
B Potentiation of metronidazole effect
C Reduction of metronidazole effect
D Potentiation of anticoagulants effect and risk of bleeding
E Reduction of anticoagulants effect
150

Apart from goods sales, there are other business transactions that can be characterized as goods disposal. Which of the following business transactions reduces stock at pharmacies?

A Reclassifying other supplies as goods
B Revaluation for packing and laboratory work
C Disposal of products for business needs
D Posting glassware
E Posting oversupply
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151

Phenobarbital drug has a sedative, soporific and anti-epileptic effect. What is its international nоnрrорrіКrоk 2 Pharmacy (англомовні студенти) 2015 рік 19 etary name?

A Nitrofurazone
B Chloramphenicol
C Diazepam
D Salol
E Luminal
152

A 70-year-old patient with stenocardia claims that the pharmacy sold him a drug that relieved an attack of stenocardia but instead caused an acute bursting headache. What antihypertensive drug can be characterized by such a side effect?

A Metoprolol
B Nifedipine
C Trimetazidine
D Amlodipine
E Nitrosorbid
153

Commercial and financial activity of a pharmacy involves using returnable packaging. Which of the following containers are returned to a supplier?

A Packaging materials
B Paper boxes
C Glassware
D Glass-stoppered bottles
E Metal cylinders
154

To make a liquid №2 by Demyanovych prescription hydrochloric acid should be taken in the following concentration:

A 0,83%
B 24,8 – 25,2%
C 98%
D 30%
E 10%
155

Menthol has anesthetic and antiseptic effect. What plant is the source of menthol?

A Folia Eucalypti
B Folia Salviae
C Folia Absinthii
D Folia Uvae ursi
E Folia Menthae piperitae
156

A drug was delivered to a private pharmacy. The chemical name of the drug active ingredient is 2-chloro-10-(3'- dimethylaminopropyl)-phenothiazine hydrochloride. Specify this drug:

A Trifluoperazine hydrochloride
B Diphenhydramine hydrochloride
C Clonidine hydrochloride
D Promethazine hydrochloride
E Chlorpromazine hydrochloride
157

A pharmacy performs both cash and non-cash transactions. Financial intermediary in the latter is a:

A Bank
B City administration
C Central regional pharmacy
D Regional control-analytical laboratory
E City administration department for pharmacy management
158

The main method of quantitative determination of corticosteroids is:

A Acidimetry
B Potentiometry
C Cerimetry
D Argentometry
E Spectrophotometry
159

Thyme grass is used for production of herbal medical products for treatment of respiratory tract infections. Under the State Pharmacopoeis of Ukraine, the raw herbal material is subject to chromatographic identification by means of thin-layer chromatography. What substances are detected on the chromatographic plate after its treatment with due reagent?

A Thymol and carvacrol
B Apigenin and luteolin
C Quercetin and rutin
D Atropine and hyoscyamine
E Arbutin and methyl arbutin
160

Specify the base for antibiotic ointments:

A 8 parts of vaseline + 2 part of lanolin
B 7 parts of vaseline + 3 part of lanolin
C 6 parts of vaseline + 4 part of lanolin
D 5 parts of vaseline + 1 part of lanolin
E 5 parts of vaseline + 5 part of lanolin
161

A pharmaceutical company plans to produce hexamethylenetetramine tablets. What production method is optimal for such tablets?

A Forming
B Compression preceded by dry granulation
C Direct compression with adjuvants
D Compression preceded by wet granulation
E Direct compression without adjuvants
162

Granulation is used to increase:

A Volume density
B Porosity
C Dissolution
D Flowability
E Breakup
163

A 46-year-old patient is diagnosed with cardiac infarction. What drug should be prescribed for thrombolytic therapy?

A Drotaverine hydrochloride
B Spironolactone (Verospiron)
C Nitroglycerine
D Streptokinase
E Trimeperidine (Promedol)
164

A patient suffering from trombophlebitis of his lower extremities has developed symptoms of heparin overdosage. What drug can be used as an antidote?

A Protamine sulfate
B Phenindione (Phenylin)
C Dipiridamol
D Theophylline
E Pentoxifylline
165

Which drug of the given below is a first aid antidote for acute poisoning caused by arsenic, mercury, chromium, and bismuth compounds?

A Prednisolone
B Adrenaline
C Atropine
D Dimercaprol (Unithiol)
E Morphine
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166

A 59-year-old patient has been using furosemide for a long time to treat his cardiac insufficiency. What drug for hypokalemia prevention should be used in the given case?

A Panangin (Potassium aspartate and magnesium aspartate)
B Thiotriazolinum
C Trimetazidine
D Acetylsalicylic acid
E Enalapril
167

A 32-year-old woman that had been undergoing antibiotic therapy for her pneumonia has developed intestine disbacteriosis. What drugs should she be prescribed?

A Antacids
B Choleretics
C Immune-response modulating agents
D Antispasmodics
E Probiotics
168

A 53-year-old woman suffers from ischemic heart disease and angina pectoris. What drug can be used to stop angina pectoris attacks?

A Dipiridamol
B Acetylsalicylic acid
C Propranolol
D Nitroglycerine
E Drotaverine hydrochloride
169

A patient is 20 years old. After she was stung by a bee the patient developed Quincke's disease; rash in the form of blisters and papulae appeared on her torso. First aid in this case should start with administering the following drug:

A Fresh frozen plasma
B Penicillin
C Prednisolone
D Haemodes
E Rheopolyglukin (Dextran)
170

A patient with osteoarthritis (gonarthrosis) and peptic gastric ulcer in anamnesis must be prescribed a NSAID (nonsteroidal antiinflammatory drug). What drug would be the most safe for this patient?

A Ibuprofen
B Acetylsalicylic acid
C Meloxicam
D Indometacin
E Metamizole sodium
171

A 20-year-old man suffers from chronic hyperacid type B gastritis. Choose the antisecretory agent.

A Levofloxacin
B Metoclopramide
C Clarithromycin
D Omeprazole
E Drotaverine hydrochlorid
172

In the course of clinical instrumental examination a 45-yearold patient was diagnosed with chronic helicobacter-associated type B gastritis. What group of drugs should be prescribed first of all?

A Anti-Helicobacter pylori agents
B Anti-Muscarinic agents
C Reparative drugs
D Antacids
E Prokinetic agents
173

What equipment is necessary to make trituration tablets?

A Double sided tabletting press machine
B Dragee pan
C Film coater
D Rotary tabletting machine
E Special tabletting machine for forming tablets
174

To perform transactions with customers it is necessary for a pharmacy to have a cash register. What cash operation is registered by a cash register as a service payment?

A Merchandise return payments
B Per diem costs
C Cash remaining in cash register at the beginning of workday
D Encashment
E Sales proceeds
175

When servicing customers it is necessary to maintain cash desk discipline. A cashier should make records in the cash book:

A Quarterly
B At the end of workday
C Monthly
D Immediately after the cash transaction occurred
E Weekly
176

Appropriate labor hours per week are being set for pharmacy staff. How many hours compose a working week for administrative staff?

A 35
B 40
C 45
D 63
E 30
177

According to the law pharmacies have the right to paid leave. Total duration of main and additional leaves cannot exceed the following number of calendar days:

A 45
B 24
C 63
D 30
E 59
178

According to the regulations of the State Pharmacopoeia of Ukraine the following solution is used to detect potassium admixture in medicinal substances:

A Hydroxyquinoline
B Sodium tetraphenylborate
C Tartaric acid
D Potassium Tetraiodomercurate Solution Alkaline
E Silver nitrate
179

What method is used for quantitative determination of antituberculous drug isoniazid according to the regulations of the State Pharmacopoeia of Ukraine?

A Bromatometry, direct titration
B Iodometry, back titration
C Bromatometry, back titration
D Acidimetry, direct titration
E Iodometry, direct titration
180

Nitrofural should be identified by chromatography according to the regulations of the State Pharmacopoeia of Ukraine. What type of chromatography is used for such identification?

A Anion-exchange
B Cation-exchange
C Thin-layer
D Gas-liquid
E Paper partition
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181

According to the regulations of the State Pharmacopoeia ofUkraine diphenylamine solution with sulfuric acid present can be used to detect the following admixtures in purified water:

A Sulfates
B Ammonium salts
C Chlorides
D Nitrates
E Heavy metals
182

To increase hydrophobic suspension stability a stabilizer is added. Name this stabilizer.

A Dimethyl sulfoxide
B Vaseline oil
C Sodium chloride
D Polysorbate 80 (Tween 80)
E Glucose
183

A pharmacy performs stocktaking to check its inventory holdings. What is the minimal interval between inventory checks of fixed assets?

A Once in 3 years
B Twice a year
C Once a year
D Once a month
E Once a quarter
184

A pharmacy performs regular stock-taking. What is the minimal interval between inventory checks of monetary funds and documents?

A Once a month
B Once in 3 years
C Once a year
D Once a quarter
E Twice a year
185

What inventory holdings of a pharmacy are included by a committee in a separate inventory during stock-taking?

A Bandaging material
B Medicines delivered to a pharmacy during stock-taking
C Medical products
D Alcoholature
E Medicinal herbs
186

Specify the norms of normal spoilage for medicinal leeches, which should be taken into account by a stock-taking committee.

A 7,6%
B 1,9%
C No norm defined
D 0,65%
E 0,85%
187

A new pharmaceutical enterprise is being founded. Which document of those given below is considered to be founding?

A Order
B Standard act
C Directive
D -
E Charter
188

A pharmaceutical firm uses a set of marketing concepts to manage its interactions with consumers. Point out one of such concepts.

A Creative marketing
B Interactive marketing
C Manufacture improvement
D Staff improvement
E Management improvement
189

What ratio is used in making hawthorn tincture?

A 1:2
B 1:10
C 1:1000
D 1:5
E 1:20
190

Name the way of injectabulettae application.

A For injection solutions of drugs
B Sublingual
C Peroral
D Vaginal
E For implantations
191

What factors affect tablet disintegration?

A Poor flowability
B High specific gravity of powders
C Amount and nature of disintegrating agents
D Tablet powder contains lamellar crystals
E Heterogeneity of granulated material
192

Hexamethylenetetramine solution sterility is achieved by:

A Pressure steam sterilization
B Gas diffusion sterilization
C Filtering through bacterial filters
D Preserving agents
E Tyndallization method of sterilization
193

During qualitative chemical analysis of nicotinic acid substance the reaction was conducted, which resulted in blue colouring. What reagent was used?

A Copper (II) sulfate solution
B Iron (III) chloride solution
C Thiocyanogen bromide reagent
D Nessler's reagent
E Sodium hydroxide solution
194

What physical constant of a substance can be used to identify diphenhydramine hydrochloride according to the regulations of the State Pharmacopoeia of Ukraine?

A Specific rotation
B Relative density
C Fusion temperature
D Refractive index
E Boiling temperature
195

Nitroxoline substance is being analysed for quantitative content of reactant by alkalimetry in non-water medium. What titrant and indicator are used in the given method?

A Sodium hydrochloride solution, phenolphthalein
B Perchloric acid solution, crystal violet
C Sodium methylate solution, thymol blue
D Sulfuric acid solution, naphtholbenzein
E Potassium hydrochloride solution, methyl orange
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196

What department of a wholesale firm is tasked with search for and analysis of potential suppliers' commercial offers, as well as concluding supply contracts and supervision of contract fulfillment?

A Finance department
B Stores development
C Supply department
D Marketing department
E Shipping department
197

Pharmaceutical market subjects that purchase drugs and medical products for further resale to make a profit, are called:

A Consumer organisations
B Government authorities
C Dealers
D Individual consumers
E Manufacturers
198

A pharmaceutical firm is unable to satisfy the demand for a drug. Specify the type of marketing tasked with decrease of excessive demand for a product by raising prices, and stopping advertising and promotion.

A Synchromarketing
B Remarketing
C Promotional marketing
D Demarketing
E Creative marketing
199

What stage of drug life cycle is characterized by a period of slow increase of sales amount, significant expenses for demand making, and absence of profit?

A Introduction
B Creation and development
C -
D Market exit
E Maturity and saturation
200

Grass of yellow hornpoppy (Glaucium flavum) contains alkaloid glaucine. What pharmacological effect does this plant have because of this alkaloid?

A Expectorant
B Anti-inflammatory
C Analgetic
D Antipyretic
E Antitussive