Крок 2 · Фармація, промислова фармація 2017 · Англійська

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01

A pharmacy prepares drugs by individual prescriptions. How often should the floors be mopped down in the prescription department?

A Once in a shift
B Once every 10 days
C Once every 3 days
D Once every 5 days
E Once in a week
02

Schedule of sanitation actions in pharmacies is regulated by the relevant regulatory acts. Cleaning day at a pharmacy must be scheduled at least once:

A In 5 days
B In 3 days
C In 10 days
D In a month
E In a week
03

A pharmaceutical company focuses on selling a diverse range of products covering different customer groups and regions. What kind of organizational structure is typical for such company?

A Centralized
B Functional
C Decentralized
D Divisional
E Bureaucratic
04

Vitali-Morin's reaction is used to identify tropane alkaloids in herbal raw material. Name the alkaloid that can be detected by means of this specific reaction:

A Platyphyllin
B Scopolamine
C Codeine
D Morphine
E Papaverine
05

Standard herbal material of lily-ofthevalley is obtained by drying it at a temperature of 50-60°C to prevent the following possible biochemical process:

A Oxidation of terpenoids
B Volatilization of essential oils
C Enzymatic hydrolysis of cardiac glycosides
D Oxidation of resins
E Oxidation of phenolic compounds
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06

A factrory workshop producing suspensions and emulsions is going to develop the manufacture of new drugs. What mechanisms can be used for the ultrasound processing of drugs?

A Rotor-pulsation apparatus, dismembrator
B Centrifugal mixer with rotating housing
C Liquid whistle, magnetostrictive source
D Dismembrator, electrical impulse plasmolyzer
E Disintegrator, liquid whistle
07

A pharmacist has made a topical solution with lipophilic vehicle. Specify the substance that produces such a type of solution:

A Menthol
B Starch
C Dermatol (bismuth subgallate)
D Sulfur
E Novocaine hydrochloride
08

A pharmacist has a labour dispute with the pharmacy administration about rescheduling his annual vacation leave. The employee can appeal against the decision of the pharmacy administration to the following body:

A Labour disputes committee (LDC)
B Trade union committee
C Highest management bodies of pharmaceutical service at the regional level
D The Ministry of Public Health of Ukraine
E Commercial court
09

Drugs derived from Rauvolfia serpentina roots are used in hypertension treatment. Authenticity of Rauvolfia serpentina herbal raw material can be confirmed by its content of:

A Reserpine
B Vinblastine
C Atropine
D Hyoscyamine
E Adonitoxin
10

Medications Passit and Novopassit are used as tranquilizing, sedative and mild hypnotic agents. These medications are produced from the following grass:

A Three-lobe beggarticks
B Garden sage
C Lesser periwinkle
D Purple passionflower
E Elecampane
11

What concept can be described as ”... an area of exchange with its characteristic system of economic relations between goods manufacturers and consumers”?

A Market
B Sales
C Management
D Agreement
E Marketing
12

To prepare a suspension a medicinal substance should be triturated with a small amount of liquid. Specify the optimal amount of liquid for trituration of 10 g of zinc oxide according to the Deriagin's rule:

A 10 ml
B 1 ml
C 5 ml
D 0,5 ml
E 2 ml
13

A pharmaceutical factory produces tablets of sodium chloride. What is the method of their poduction?

A Wet granulation prior to compression
B Direct compression without additional substances
C Direct compression with the addition of excipients
D Dry granulation prior to compression
E Moulding
14

Various types of dryers can be used for granule dehumidification. Specify the type of ”СП-30” dryer:

A Silica gel dryer
B Freeze dryer
C Forced air dryer
D Fluidized bed dryer
E Infrared dryer
15

Ampoule workshop of a factory produces 5% oil solution of tocopherol acetate for injections. What method of filling the ampoules is optimal in this case?

A Syringe
B Syringe and devaporation
C Vacuum
D Syringe and vacuum
E Devaporation
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16

An analyst of a chemical laboratory had received a glucose substance for analysis. To check its quality he used a polarimeter. The analyst measured:

A Melting point
B Refractive index
C Optical density
D Specific gravity
E Angle of rotation
17

A doctor has prescribed pessaries of unspecified mass. What mass should be chosen when pessaries are being prepared in a pharmacy?

A 6,0
B 4,0
C 0,5
D 3,0
E 1,5
18

A pharmacist has made an injection solution that contains a salt produced by reaction of a strong base with a weak acid. Specify the necessary stabilizer:

A Ascorbic acid
B Sodium hydrochloride
C Sodium sulfate
D Hydrochloric acid
E Cysteine
19

Collective labour agreement is concluded by a trade union committee with the business owner on behalf of the workforce. Any collective agreement is worked out in written form. Which article of the Labour Code regulates the duration of the collective agreement?

A 41
B 38
C 40
D 36
E 17
20

A pharmacist prepares cocoa butterbased round vaginal suppositories with less than 5% of citric acid. Specify the most rational approach to introduction of the active ingredient into the vehicle:

A Dissolve in molten cocoa butter
B Dissolve in Dimexid (Dimethylsulfoxide)
C Dissolve in minimal quantity of purified water
D Dissolve in vaseline oil
E Dissolve in alcohol
21

A pharmacist prepares an injection solution that must be stabilized with 0,1M of hydrochloric acid solution. What solution is to be prepared?

A Sodium benzoate
B Novocaine
C Potassium chloride
D Calcium chloride
E Hexamethylenetetramine
22

.Apharmacist hasmade a drug by the prescription:
Rp.: Sol. Protargoli 0,31,0 D.S. For irrigation. Specify the optimal technology of preparation:

A Dissolve protargol in the water, add glycerine
B Grind protargol in the mortar with glycerine, add water
C Dissolve glycerine in the water, add protargol
D Measure out protargol into the vial, dissolve it in the water, add glycerine
E Measure out subsequently glycerine, water, and protargol into the vial
23

Paracetamol substance has been sent for analysis. Reaction with the solution of iron (III) chloride resilted in the blue-violet coloring. This indicates the presence of:

A Aldehyde group
B Phenolic hydroxyl
C Keto group
D Alcoholic hydroxyl
E Ester group
24

Production of tablets requires stagetostage quality control. What devices are used to determine the particle size distribution (fraction) of granules?

A Microscope
B Various vibrosieves
C Laboratory identifiers
D Standard set of sieves
E Friabilators
25

An analytical laboratory has received a procaine hydrochloride substance for analysis. According to the State Pharmacopoeia ofUkraine limit content of heavy metals should be determined with the following reagent:

A Methoxyphenylacetic acid
B Thioacetamide
C Sulfomolybdenum
D Aminomethyl alizarin acetic acid
E Hypophosphite
26

Preparations of sorrel roots can have both a laxative and astringent effect. This is due to the presence of the following biologically active substances:

A Flavonoids and essential oils
B Iridoids and vitamins
C Coumarins and phenol glycosides
D Essential and fatty oils
E Anthracene derivatives and tannins
27

Which of the pharmacy departments is responsible for checking the quantity and quality of received goods, their storage and dispensing to other departments?

A Department of over-the-counter drugs
B Department of curative cosmetics
C Inventory department
D Compounding and production department
E Department of finished dosage forms
28

Chloride of lime is identified by calcium cations after boiling with acetic acid in order to eliminate active chlorine. What reagent is used?

A Magnesium sulfate
B Ammonium oxalate
C Potassium chloride
D Sodium nitrite
E Ammonium molybdate
29

A set of values, traditions, behavioral norms, and views inherent to an organisation characterizes its following feature:

A Capitalization level
B Culture
C Success
D Profitability
E Self-development capability
30

A patient needs the pharmacy to prepare him a camphor ointment. What concentration of camphor should be in the ointment according to the regulatory documents?

A 20%
B 15%
C 1%
D 5%
E 10%
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31

A manufacturing company initiates changes to the package insert of a drug, which are aimed at limitation of its use. What type of marketing is used by the company in this case?

A Counteractive
B Synchromarketing
C Conversion
D Remarketing
E Stimulating
32

For better coverage of various markets the Lubnyfarm company sells a portion of its production through its chain of pharmacies, another portion is being sold through distributors, and the third - through pharmacies of another owners. What marketing system of distribution is used by this company?

A Corporate
B Horizontal
C Contractual
D Administered
E Multichannel
33

One of the most important market characteristics is a goods economic trend. What economic trend can be characterized by relative stability of high prices and the highest activity of manufacturers and customers?

A Low
B Downward
C Subsiding
D Sluggish
E High (stable)
34

A pharmacy prepares 10% sodium chloride injection solution. What sterilization would be optimal in this case?

A Irradiation sterilization
B Sterile filtration through membrane
C Dry-heat sterilization
D Autoclave chamber with highpressure saturated steam
E Gas sterilization
35

Prior to making a sodium chloride isotonic solution a pharmacist baked the powder in a dry heat box. What substances are removed by this operation?

A Pyrogenic substances
B Moisture
C Chlorides
D Redox substances
E Sulfates
36

A pharmacy has received a prescription for tincture. What herbal raw material can be used tomake this dosage form?

A Oak bark
B Rhubarb roots
C Valerian rootstock
D Buckthorn bark
E Arrow-wood bark
37

A certain type of herbal raw material is being collected in spring during sap flow. Specify this material:

A Infructescences
B Roots
C Buds
D Bark
E Flowers
38

A medical product reaches its final consumer according to the following scheme: manufacturer / wholesale house / pharmacy / final consumer. Determine the level of the distribution channel:

A Three-level channel
B Four-level channel
C Two-level channel
D One-level channel
E Zero-level channel
39

A pharmacist has prepared a drug by the prescription:
Rp.: Olei Helianthi 7,4 Solutionis Ammonii caustici 2,5 ml Асіdі oleinici 0,1 M. D. S:. Ammoniac liniment. For infriction. Specify the type of disperse system:

A Liniment-solution
B Combined liniment
C Liniment-emulsion
D Extractive liniment
E Liniment-suspension
40

A pharmacist has prepared a drug by the prescription:
Rp.: Streptocidi Dermatoli ana 1,0 Lanolini Vaselini ana 5,0
M.D.S.: Apply to the affected skin. Specify the type of the disperse system:

A Solution ointment
B Combined ointment
C Extraction ointment
D Suspension ointment
E Hydrophilic ointment
41

Optical rotation angle of substances is determined under the temperature of 20°C, in 1-decimeter-thick layer, with wavelength of sodium spectrum D-lines (λ = 589,3 nm), and is calculated with reference to a solution containing 1 g of the substance per ml. It is called:

A Specific optical rotation
B Refractive index
C Relative density
D Distribution coefficient
E Optical density
42

Which of the following antibiotics can be identified by means of maltol test?

A Streptomycin sulfate
B Doxycycline hydrochloride
C Amoxicillin
D Lincomycin hydrochloride
E Kanamycin monosulfate
43

Specify the control methods aimed at detecting mechanical impurities in parenteral solutions:

A Amperometric
B Limulus test
C Visual optical
D NMR and UV-visible spectroscopy
E Gravitational
44

Adonis-derived drugs are popular cardiotonic agents. The stock of adonis herbal raw material is assessed by the method of:

A Model specimen
B Permanent quadrates
C Geodesic
D By eye
E Projective cover
45

A pharmaceutical analyst identifies the substance of potassium acetate. What reagent confirms the presence of potassium cation in the substance?

A Potassium permanganate
B Zinc oxide
C Tartaric acid
D Iron (III) chloride
E Sodium hydroxide
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46

An analytical chemist performs the qualitative assessment of mercury (II) chloride.What method is recommended by the State Pharmacopoeia of Ukraine for quantitative assessment in this case?

A Acidimetry
B Alkalimetry
C Nitritometric titration
D Bromometry
E Complexometric titration
47

The market can be characterized by the following conditions: there are many sellers and buyers, who have no influence over current prices; similar and interchangeable competing goods are available; there are no price limits. What type of market is it?

A Pure competition
B Economic planning
C Oligopoly
D Pure monopoly
E Monopolistic competition
48

Specify the indicator that measures the total contribution of various solutes to the osmotic pressure of the solution:

A Isotonicity
B Apyrogenicity
C Isohydricity
D Osmolality
E Isoviscosity
49

Dosage precision during tabletmaking mainly depends on the following technological property of tablet mass:

A Lyophilic property
B Flowability
C Compressibility
D Compression ratio
E Relative density
50

A pharmacy opens a bank account to store funds and conduct ongoing business transactions. What kind of account should be opened?

A Investment
B Deposit
C Provisional
D Letter of credit
E Current
51

Manufacturer'smarketing department detected negative demand for a certain goods. What would be the marketing task? What type of marketing should be applied?

A Demand leveling, synchromarketing
B Demand increase, remarketing
C Demand decrease, demarketing
D Demand making, conversion marketing
E Demand stimulation, promotional marketing
52

To confirmthe presence of sulfat ions in themedicinal preparation ofmagnesium sulfate an analytical chemist of a pharmacy uses the following solutions:

A Ammonium chloride and ammonium hydrate
B Benzenesulfonic acid
C Barium chloride and hydrochloric acid
D Silver nitrate and nitric acid
E Diphenylamine
53

Natural persons registered as small business entities with simplified taxation scheme are subject to limitation of the annual amount of sales proceeds. Specify the proceeds limit:

A 750 000 UAH
B 5 000 000 UAH
C 100 000 UAH
D 3 000 000 UAH
E 500 000 UAH
54

Quality of dried extracts is assessed according to several criteria. Specify the highest acceptable amount of moisture in dried extracts according to the State Pharmacopoeia of Ukraine:

A 20%
B 25%
C 75%
D 95%
E 5%
55

When preparing dermatological ointments the following substance should be introduced by suspending:

A Ephedrine hydrochloride
B Protargol (silver proteinate)
C Camphor
D Xeroform
E Menthol
56

What is the function of anhydrous lanolin in the suppository mass used for suppositories prepared via hand rolling?

A Preservative
B Emollient
C Solubilizer
D Plasticizer
E Solvent
57

An analytical chemist analyses the substance of racemic menthol according to the State Pharmacopoeia of Ukraine. To identify the drug and determine its purity he uses optical rotation that should occur within the interval:

A From +50o to +56o
B From +0, 2o to –0, 2o
C From – 48o to –51o
D From –102o to –105o
E From +10o to +13o
58

Codeine is used as a coughdepressant. What herbal raw material contains this alkaloid?

A Grass of common periwinkle
B Celandine grass
C Grass of plume poppy
D Pods of opium poppy
E Tea leaves
59

What herbal drug produced form alkaloid-containing raw materials can be recommended for neurasthenia, insomnia, menopausal disorders?

A Securinine nitrate
B Ergotamine
C Vinblastine
D Glaucine hydrochloride
E Novopassit
60

An analytical chemist can quantitatively determine the thiamine bromide content in powders by means of:

A Nitritometric titration
B Bromometry
C Complexometric titration
D Permanganatometry
E Alkalimetry
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61

What technology should be chosen by a pharmacist to make a liquid dosage form, if it contains calcium gluconate?

A Dissolve in the water free of redox subsatances
B Dissolve in alkaline medium
C Dissolve it in hot solvent or heat it up to full dissolution
D First grind it into powder when it is dry or with small amount of solvent added
E Add equal amount of sodium chloride
62

Tyndallization is used at a pharmaceutical factory as one of sterilization methods for thermolabile substances. What is the essence of this method?

A Triple heating of solution to 40-60°C with 24-hour-long intervals in between for thermostating
B Autoclaving at 119-121°C with pressure at 1,0-1,1 atm
C Sterilization with high-frequency and microwave frequency current
D Sterilization with flowing steam at 100°C
E Sterilization with dry heat at 180200°C for a lengthy period of time
63

What final document is used for the preparation of the report on the discrepancies revealed in the course of inventory at the pharmacy?

A Commercial report
B Inventory item description
C Act on the inventory results
D Checklist
E Invoice
64

A teenager with hyporexia has been recommended to drink medicinal herbal tea of the following composition: Herba Absinthii, Herba Millefolii. Specify the characteristic microscopic features of Artemisia absinthium, which indicate its presence in the herb mixture:

A Retor-shaped hairs
B T-shaped hairs along the leaf edge
C Branched, simple and ciliated hairs
D Branched and capitate hairs
E Simple and capitate hairs
65

A patient suffering from bronchial asthma was diagnosed with essential hypertension. What antihypertensive drug is contraindicated for this patient?

A Propranolol
B Verapamil
C Hypothiazid (Hydrochlorothiazide)
D Captopril
E Amlodipine
66

In the process of isoniazid identification a pharmacy analyst thoroughly boiled the substance with 2,4dinitrochlorobenzene. The substance turned yellow. After adding alkaline solution the substance turned first violet and then brownish-red. As the result of this reaction the following aldehyde derivative is produced:

A Gluconic
B Glyoxylic
C Glutamic
D Hexanic
E Glutaconic
67

Indometacine is a nonsteroidal antiinflammatory drug. A condensed heterocyclic system is contained within the structure of this drug. What cycles compose the system?

A Benzene and thiazole
B Two 4-oxycoumarin residues
C Pyrimidine and imidazole
D Pyrrole and benzene
E Benzene and pyridine
68

A 43-year-old patient with a severe form of rheumatoid arthritis has been administered a certain drug for background therapy. Specify this drug:

A Prednisolone
B Nimesulide
C Methylprednisolone
D Methotrexate
E Diclofenac sodium
69

A process dealing with drawing the documents, their processing, circulation and storage is called records management. If all documents circulate through one organization center, - the Office Desk, - then such system of records management is called:

A Referent
B Centralized
C Specialized
D Decentralized
E Mixed
70

Representatives of the family Solanaceae are widely used in medical practice as alkaloid-containing plants. Which representative is the source for production of semi-synthetic steroid hormones?

A Hyoscyamus niger
B Solanum laciniatum
C Atropa belladonna
D Datura Stramonium
E Solanum tuberosum
71

Birch buds are used as a diuretic. Quality of the herbal raw material is determined by its content of:

A Essential oil
B Iridoids
C Saponins
D Vitamins
E Lipids
72

A pharmaceutical manufacturer sets the price for a drug basing on its prime cost with premium. What model of pricing is it?

A Cost-based
B Demand-based
C Competitive
D Breakeven
E Supply-based
73

At the end of each month a pharmacy accountant draws up a balance. What indicator characterizes liabilities of a pharmaceutical company?

A Equity capital
B Reserves and expenses
C Work-in-process inventory
D Accounts receivable
E Circulating assets
74

What method is recommended by the State Pharmacopoeia of Ukraine for quantitative determination of potassium chloride substance that is used in treatment of hypokalemia?

A Iodometry
B Polarimetry
C Bromatometry
D Cerimetry
E Argentometry
75

Who is responsible for the acceptance of goods and medical products with accompanying incoming quality control?

A Pharmacy head manager
B Dispensing chemist
C Authorized representative
D Supplier pharmacist
E Analyst
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76

A 35-year-old patient with tachycardia has been administered propranolol. Which of the following reactions may be caused by the use of ?-blockers?

A Cumulation
B Bronchospasm
C Drug dependence
D Blood pressure rise
E Constipations
77

Infuser apparatus is used by a pharmacy to prepare:

A Infusion solutions
B Emulsions
C Ointments
D Infusions and decoctions
E Suspensions
78

Lately the Phytopharmpharmaceutical company has been forced to decrease its production volume and range of goods. Not only does the company head manager demonstrate no managerial abilities, but he also appears to be completely disinterested in the running of the business and executes no control over it. Determine the leadership type of the head manager in this case:

A Authoritarian
B Liberal
C Democratic
D Directive
E Autocratic
79

Phytochemical workshop of a factory manufactures pancreatin. What is the source material for obtaining pancreatin?

A Heart of cattle
B Gastric mucosa of pigs
C Pancreas of pigs or cattle
D Lungs of cattle
E Egg white
80

The following substance is used as an extractant in production of liquid extracts:

A Glycerine
B Acetone
C Chloroform
D Dichloroethane
E Ethanol
81

Which of the following diuretics SHOULD NOT be given to the patients with impaired hearing?

A Chlorthalidone
B Spironolactone
C Clopamide
D Furosemide
E Indapamide
82

A patient, who has been taking acetylsalicylic acid, developed hemorrhages of mucous membranes. This phenomenon is associated with:

A Inhibition of the prothrombin synthesis
B Changed volume of distribution
C Disorder of protein binding
D Decreased absorption in the gastrointestinal tract
E Increased absorption in the gastrointestinal tract
83

Simultaneous application of doxycycline hydrochloride and oral contraceptive causes:

A Increase of oral contraceptives effectiveness
B -
C Increase of the antibacterial effect of doxycycline
D Reduction of the antibacterial effect of doxycycline
E Reduction of oral contraceptives effectiveness
84

To treat iron-deficiency anemia the following drug is usually prescribed:

A Corticosteroids
B Vicasol (Menadione)
C Ferroplex
D Heparin
E Furagin (Furazidinum)
85

A 70-year-old patient with stenocardia claims that the pharmacy had sold him a drug that relieved an attack of stenocardia but instead caused an acute bursting headache. What antihypertensive drug is this side-effect typical of?

A Amlodipine
B Nitrosorbid
C Nifedipine
D Metoprolol
E Trimetazidine
86

Presence of nitrate radical in metronidazole structure can be confirmed by reduction of nitrate radical to amino group with production of:

A Iodoform
B Thiochrome
C Azo dye
D Indophenol
E Murexide
87

Xycaine quantitative content can be determined by means of argentometry (back titration).What indicator is required by this method?

A Iron (III) ammonium sulphate
B Sodium eosinate
C Potassium chromate
D Starch
E Bromphenol blue
88

A dispensing chemist with calculated length of service of 7 years has fallen ill. What percent of the sum stated in her sick list would she receive?

A 60%
B 80%
C 100%
D 50%
E 70%
89

Commercial and financial activity of a pharmacy involves using returnable tare. Which of the following containers are returned to the supplier?

A Paper boxes
B Metal cylinders
C Glass-stoppered bottles
D Glassware
E Packaging materials
90

A pharmacy has received goods from a warehouse, which were delivered by the warehouse transport. Therefore, goods receipt requires the following accompanying document:

A Financial statement of the supplier
B All of the listed
C Contract of delivery
D Specifications to the contract of delivery
E Motor waybill
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91

Specialists of a pharmaceutical enterprice confirm the identity of Cassia acutifolia herbal raw material. During reaction with alkali it developed cherryred coloring. What substances were identified?

A Tannins
B Iridoids
C Anthraquinones
D Alkaloids
E Glycosides
92

Number of mediators that pharmaceutical goods pass on their way from manufacturer to consumer is called:

A Volume of distribution channel
B Width of distribution channel
C -
D Level of distribution channel
E Length of distribution channel
93

Menthol has anesthetic and antiseptic effect. What plant is the source of menthol?

A Folia Absinthii
B Folia Uvae ursi
C Folia Salviae
D Folia Menthae piperitae
E Folia Eucalypti
94

The main method of quantitative determination of corticosteroids is:

A Argentometry
B Acidimetry
C Potentiometry
D Spectrophotometry
E Cerimetry
95

The thyme grass is used for the production of herbal medical products for the treatment of respiratory tract infections. Under the State Pharmacopoeia of Ukraine the herbal raw material is subject to chromatographic identification by means of thin layer chromatography. What substances are detected on the chromatographic plate after its treatment with due reagent?

A Apigenin and luteolin
B Thymol and carvacrol
C Quercetin and rutin
D Arbutin and methyl arbutin
E Atropine and hyoscyamine
96

A pharmacy offers to its customers a chance to measure their blood pressure. What type of goods is it?

A Unsought goods
B Specialty goods
C Nondurable goods
D Convenience goods
E Service
97

Several independent mediators work in resale of medical equipment. What group of mediators includes persons and legal entities that specialize in sales of durable goods that require considerabe after-sales service?

A Dealer
B Broker
C Agent
D Commission agent
E Consignee
98

Propellants are used in aerosols production. Specify the function of propellants:

A Stabilization
B Dispersion
C Create pressure in the package
D Action prolongation
E Emulsification
99

The chemical name of 2,2(diphenylmethoxy)-N,N-dimethylethanamine hydrochloride corresponds with the following medicinal substance:

A Ethylmorphine hydrochloride
B Diphenhydramine hydrochloride
C Papaverine hydrochloride
D Lidocaine hydrochloride
E Ciprofloxacin hydrochloride
100

An analytical chemist should use the following solution to identify sodium-containing substances:

A Sodium citrate
B Potassium permanganate
C Potassium carbonate
D Potassium pyroantimonate
E Barium hydroxide
101

Calcium gluconate is being tested for presence of admixtures of saccharose and reducing sugars with copper-tartrate reagent. If these admixtures are present the substance colors:

A Green
B Turquoise
C Red
D Blue
E White
102

A 45-year-old man has been taking long-acting nitrates twice a day for a year. Currently the decrease in effectiveness of the pharmacotherapy is being observed. What side-effect can be suspected in the first place?

A Progressing coronary atherosclerosis
B Progressing ischemic heart disease
C Myocardial infarction
D Development of nitrate tolerance
E Impairment of coronary circulation
103

A 43-year-old patient was delivered to an admission room with renal colic attack. What group of drugs would be the most effective during the attack?

A Cholagogues
B Antibiotics
C Hepatoprotectors
D Antispasmodics
E Antacids
104

What antibiotic has beta-lactam cycle in its structure?

A Streptomycin sulfate
B Chloramphenicol
C Doxycycline hyclate
D Benzylpenicillin potassium salt
E Lincomycin hydrochloride
105

Incoming medicines inspection is performed by an authorized employee. What is NOT a part of the responsibilities of this person?

A To draw up orders for medicines and medical products, to conclude sales contracts
B To keep a roster of incoming medicines
C To check the pharmacy stock for low-quality or fake medicines
D To draw up conclusions regarding inspection of incoming medicines
E -
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106

A pharmacist has prepared a liquid mixture. What component was added last into the vial?

A Tincture of valerian
B 20% sodium bromide solution
C Simple syrup
D Potassium bromide
E Purified water
107

What hypotensive drug is an agent of choice for the patients suffering from arterial hypertension with concomitant type I diabetes mellitus?

A Carvedilol
B Hydrochlorothiazide
C Atenolol
D Labetalol
E Lisinopril
108

Snake venom-based drugs are widely applied in treatment of locomotor apparatus diseases.Main components of these venoms are:

A Glucosinolates
B Cardiac glycosides
C Toxic proteins
D Alkaloids
E Phenol-alcohols
109

A 25-year-old man is diagnosed with acute pyelonephritis of moderate severity. What drugs should be prescribed for etiotropic therapy?

A Glucocorticoids
B Anticholinesterase drugs
C Antimicrobial agents
D Nonsteroidal antiinflammatory drugs
E Antiarrhythmic drugs
110

The chemical name of 2benzyl-1H-benzimidazole hydrochloride corresponds with the following medicinal substance:

A Omeprazole
B Dibazol (Bendazolum)
C Indometacin
D Phenazepam
E Vicasol (Menadione)
111

Pharmacy premises can be divided into service rooms and workrooms. Name the workroom for storage of medical products:

A Washing room
B Shop floor
C Aseptic block
D Distillation room
E Material storage room
112

Identification of potassium iodide requires performing an oxidation reaction in acid medium, which produces free iodine that colors chloroform layer. What reagent is used for such a reaction?

A Ammonium oxalate
B Silver nitrate
C Sodium carbonate
D Barium chloride
E Sodium nitrite
113

An analytical chemist determines potassium ions admixture in a medicinal substance with sodium tetraphenylborate according to the State Pharmacopoeia of Ukraine. What analytical effect would confirm the presence of this admixture?

A White opalescence
B Blue coloring
C Pink coloring
D Yellow coloring
E Brown coloring
114

The cholagogue derived from Rosa canina fruit is used in treatment of liver and gallbladder diseases. Name this drug:

A Altan
B Chophytol
C Cholosas
D Allochol
E Phytolyt
115

According to the rules in force, workrooms should regularly undergo humid disinfection. How often should the floors be washed?

A No less than thrice in a week
B No less than once in a week
C No less than twice in a week
D No less than once in a shift
E No less than twice in a month
116

Senna (cassia) foliage contains anthracene derivatives. Their presence can be confirmed by qualitative reaction with:

A Alkali
B Iron (II) sulfate
C Fehling's reagent
D Iron ammonium alum
E Molisch's reagent
117

A private pharmacy has received a supply of a drug with 2,3-dihydro-2methyl-1,4-naphthoquinone-2-sulfonate sodium as an active ingredient. Name this drug:

A Cocarboxylase hydrochloride
B Vicasol (Menadione)
C Riboflavin
D Ergocalciferol
E Rutin
118

A 53-year-old woman suffers from ischemic heart disease and angina pectoris. What drug can be used to stop angina pectoris attacks?

A Dipiridamol
B Acetylsalicylic acid
C Nitroglycerine
D Drotaverine hydrochloride
E Propranolol
119

A patient is 20 years old. After she was stung by a bee the patient developed Quincke's disease; rash in the form of blisters and papulae appeared on her torso. First aid in this case should start with administering the following drug:

A Fresh frozen plasma
B Haemodes
C Rheopolyglukin (Dextran)
D Penicillin
E Prednisolone
120

What department of a wholesale firm is tasked with search for and analysis of potential suppliers' commercial offers, as well as concluding supply contracts and supervision of contract fulfillment?

A Marketing department
B Supply department
C Finance department
D Stores development
E Shipping department
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121

To prepare eyedrops with antibiotic a dispensing chemist has been using flowing steam sterilization under 100°C for 30 minutes. What antibiotic allows for such sterilization?

A Biomycin
B Erythromycin
C Streptomycin sulfate
D Levomycetin (Chloramphenicol)
E Sodium benzylpenicillin
122

A certain drug explodes when heated to 180°C or upon impact and, therefore, must be handled carefully during receipt and storage. This drug is:

A Alcoholic iodine solution
B Nitroglycerine solution
C Activated carbon
D Calcium chloride
E Barium chloride
123

Gum is a polysaccharide substance that contains calcium and magnesium salts of uronic acids and neutral monosaccharides. By solubility arabin, bassorin, and cerasin derivatives can be distinguished. What gum is insoluble in cold water?

A Acacia
B Cherry
C Apricot
D Tragacanth
E Plum
124

A pharmacy prepares a drug that contains a high-molecular compound with unlimited swelling ability. Name this material:

A Methylcellulose
B Pepsin
C Starch
D Protargol
E Gelatine
125

The Financial Report of a pharmacy for the first quarter of 20XX contains the following entries: goods turnover - 45 000 UAH, production cost of products sold - 30 000 UAH, turnover costs - 10 000 UAH. Determine the income:

A 15 000 UAH
B 35 000 UAH
C 40 000 UAH
D 5 000 UAH
E 30 000 UAH
126

In Ukraine the auditor position eligibility requires the candidate to be a Ukrainian citizen and have the qualification certificate for work as an auditor within the Ukraine's territory. The certificate is effective for:

A 5 years
B 3 years
C 2 years
D Indefinitely
E 1 years
127

A man with gastric ulcer is prescribed anti-Helicobacter pylori therapy. On the 3rd day the patient developed black coloring of feces.What had caused such changes?

A Tetracycline
B Omeprazole
C Metronidazole
D Bismuth subcitrate
E Tinidazole
128

A certain drug can be quantitatively assessed by means of direct alkalimetry in glycerine, mannitol, or other polyhydric alcohol medium. This drug is:

A Acetylsalicylic acid
B Boric acid
C Glutaminic acid
D Benzoic acid
E Salicylic acid
129

Hydrogen sulfide is being produced in the process of dry pyrolysis of a certain sulfanilamide drug. Name this drug:

A Sulfadimezinum (Sulfadimine)
B Streptocide
C Norsulfazole
D Sulfacil sodium
E Soluble streptocide
130

1,8-cineole is a bactericidal component of essential oil. Specify the medicinal herb that is grown in Ukraine and contains 1,8-cineole in its essential oil:

A Eucalyptus globulus
B Salvia officinalis
C Origanum vulgare
D Inula helenium
E Juniperus communis
131

The Dobropharma pharmacy manager makes plans for standard stock of various groups of goods, based on their purpose. Convenience goods belong to the following group:

A Specific demand
B Current demand
C Seasonal accumulation
D Prior delivery
E Single delivery
132

Accounts receivable develop in the process of pharmaceutical company work. Specify where in the balance book they are recorded:

A Account
B Liabilities
C Credit
D Assets
E Debit
133

A pharmacy has received a prescription for colloid solution. Name this solution:

A Collargol solution
B Nonaqueous solution
C Burow's solution
D Sodium chloride solution
E 5% glucose solution
134

A technological controller uses Marquis reagent to identify the substance of acetylsalicylic acid after acid hydrolysis. Positive effect of the reaction would be indicated by the following coloring:

A Violet
B Yellow
C Green
D Blue
E Pink
135

A 3-year-old child is intolerant to paracetamol. What antipyretic drug can be taken instead?

A Nimesulide
B Diclofenac sodium
C Naproxen
D Acetylsalicylic acid
E Ibuprofen
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136

.Apatient with angina pectoris takes long-acting nitrates. Consult him what side-effect is the most common for these drugs:

A Vomiting
B Headache
C Nausea
D Diarrhea
E Constipation
137

Essential oil of a certain plant contains up to 80% of cineole. Specify the herbal raw material that is collected from this plant:

A Folia Absinthii
B Folia Menthae piperitae
C Folia Betulae
D Folia Меlіssае
E Folia Eucalypti
138

.According to the State Pharmacopoeia of Ukraine quantitative content of salicylic acid is to be determined by means of:

A Complexometric titration
B Acidimetry
C Argentometry
D Alkalimetry
E Nitritometric titration
139

.Apharmacist prepares a chamomile flowers infusion. Specify the proportion of raw material to infusion:

A 1:30
B 1:400
C 1:10
D 1:20
E 1:50
140

50 ml of injection solution has been made in a pharmacy. Specify the process of solution sterilization:

A 140°C - 12 minutes
B 110°C - 15 minutes
C 180°C - 30 minutes
D 160°C - 15 minutes
E 120°C - 8 minutes
141

An important indicator of business activity is profitability of a business. Specify the indicators that can be used to measure the profitability:

A Turnover/production cost
B Income/turnover
C Liquidity/solvency
D Turnover/income
E Profit/turnover
142

Genetically induced adverse reaction to a certain drug is caused by various enzyme defects. Name this reaction:

A Withdrawal syndrome
B Rebound effect
C Dysbiosis
D Idiosyncrasy
E Steal syndrome
143

Difference between the retail price of products sold and themargin determines:

A Markup
B Margin
C Breakeven
D Income
E Production cost
144

A pharmaceutical company produces essential oils via a method that consists of essential oil transfer into gas phase followed by its absorption with fats and then its extraction with alcohol. Name this method:

A Enfleurage
B Extraction
C Dynamic sorption
D Compression
E Hydrodistillation
145

To identify cardiac glycosides there are usually three groups of color reactions being performed: for steroid nucleus, for lactonic ring, and for carbohydrate component. Specify the reaction for identification of butenolide ring:

A Reaction of sublimation
B Dragendorff's test
C Legal's test
D Mayer's test
E Stahl's reaction
146

A 43-year-old woman has come to a pharmacy with complaints of sharp headache in the occipital area, palpitations, ”visual snow” in her eyes, nausea; her BP is 180/110 mm Hg. These symptoms correspond with:

A Migraine attack
B Exertional angina pectoris attack
C Hypertensic crisis
D Acute conjunctivitis
E Cervical osteochondrosis
147

Medicinal substance had been received for chemical analysis. Biuret test was performed for identification. Name this substance:

A Dipyrone (Metamizole)
B Iodoform
C Benzoic acid
D Bromisoval
E Diphenhydramine
148

A patient, who has undergone treatment for community-acquired pneumonia, complains of hearing impairment. What antibacterial drug could result in such a side-effect?

A Cefazolin
B Clarithromycin
C Gentamicin
D Amoxicillin/clavulanate
E Ciprofloxacin
149

A 36-year-old woman with herpetic rash on her lips has come to a pharmacy. Recommend her a drug for topical treatment:

A Amikacin
B Fluconazole
C Acyclovir
D Metronidazole
E Levofloxacin
150

A pharmaceutical company produces mint tincture. Technological process of making this tincture requires it to be made:

A With 70% alcohol in 1:5 proportion
B With 48% alcohol in 1:2 proportion
C With 70% alcohol in 1:15 proportion
D With 90% alcohol in 1:20 proportion
E With 70% alcohol in 1:10 proportion
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151

Several species of Polygonum genus are used inmedicine. One of these species has rootstocks rich in tanning agents, which are used to treat diarrrhea. Name this species:

A Polygonum bistorta
B Polygonum aviculare
C Polygonum alpinum
D Polygonum hydropiper
E Polygonum persicaria
152

A 65-year-old man with community-acquired pneumonia was prescribed antibiotic agent amikacin. It should be kept in mind, that amikacin has the following side-effect:

A Ototoxicity
B Vomiting
C Decreased blood pressure
D Red coloring of urine
E Increased blood pressure
153

Considering thermolability of most animal-derived injection preparations, they are sterilized by means of:

A Ultrasound
B In autoclave chamber with highpressure saturated steam
C Addition of buffer solutions
D Filtration through membrane
E High frequency current
154

Sodium and potassium oxides are introduced into the ampoule glass to:

A Increase its chemical stability
B Increase its thermal stability
C Increase its mechanical stability
D Increase its dimming ability
E Decrease its melting point
155

Hierarchic structure of the Agapetus pharmacy management foresees that authority is being passed on directly from the pharmacy manager to the employees. Specify this type of authority:

A Line and staff
B Functional
C Line
D Divisional
E Matrix
156

Several cholesterol gallstones are detected in the gallbladder of a woman. Choose the drug to dissolve and excrete the stones:

A Loperamide
B Domperidone
C Platyphyllin
D Papaverine
E Ursodeoxycholic acid
157

What indicator is used in iodometry for quantitative determination of caffeine in caffeine and sodium benzoate?

A Potassium chromate
B Eriochrome black
C Methyl orange
D Starch
E Bromthymol blue
158

An accountable person has received a sum of money from the pharmacy cash desk to buy a calculator. What document records the cash flow in such a transaction?

A Remains unregistered documentarily
B Receipt
C Cash expense order
D Cash income order
E Invoice
159

A pharmaceutical company produces tablets. Tabletting by means of direct compression requires:

A Prior homogenization
B Formation of masses
C Application of hydraulic press
D Prior granulation
E No prior granulation
160

A pharmaceutical company produces aromatic waters. Peppermint water should be prepared in the following proportion:

A 1:2000
B 1:1
C 1:4000
D 1:1000
E 1:10
161

A young mother has come to a pharmacy to buy an antipyretic drug for her 3-month-old infant.What dosage form would you choose for the infant?

A Tablets
B Capsules
C Spray
D Suppositories
E Lozenges
162

The management plans to open a new pharmacy in one of the local villages. Such activity can be identified as:

A Conglomerate diversification
B Vertical integration
C Growth strategy
D Horizontal diversification
E Horizontal integration
163

To minimize business risks, the board of directors of a pharmaceutical company decides to expand into a market of plant protection products. Such approach to risk management is called:

A Consolidation
B Insurance
C Diversification
D Integration
E Intensification
164

Publicly-owned Isotope factory is the only manufacturer of radiopharmaceuticals inUkraine.What type of distribution is characteristic of radioactive drugs?

A Sample
B Selective
C Intensive
D Bulk
E Exclusive
165

A 28-year-old woman came to a pharmacy complaining of constipation that developed after antacid treatment. What drug could be the cause of this symptom?

A Simethicone
B Calcium carbonate
C Magnesium-containing drugs
D Aluminium-containing drugs
E Ranitidine
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166

A 60-year-old man has come to a pharmacy with complaints of impaired twilight vision, dry sclera, cracked and peeling skin. The dispensing chemist suspected hypovitaminosis and recommended the customer to take the following drug after consultation with the physician:

A Ascorbic acid
B Tocopherol acetate
C Vicasol (Menadione)
D Ergocalciferol
E Retinol acetate
167

A pharmaceutical company produces Lugol's iodine solution. By type of solvent this solution belongs to the following group:

A Water solutions
B Alcohol solutions
C Chloroform solutions
D Oil solutions
E Glycerine solutions
168

A patient was prescribed an oral antibiotic for treatment and an antacid to remove heartburn symptoms. If the drugs are taken simultaneously their interaction can result in the following:

A Mutual potentiation
B Relative overdosage
C Acceleration of metabolism and excretion
D Antibiotic malabsorption
E Inhibition of hepatic microsomal enzymes
169

Medicinal dyes should be stored in a special cabinet. Which of the listed medical products is a dye:

A Ethyl alcohol
B Hydrogen peroxide
C Ascorbic acid
D Glucose
E Brilliant green
170

Calendula Ointment is placed on the shelf next to Dr. Theiss Calendula Ointment. What approach to the shelf layout is used in this pharmacy?

A Corporate block layout
B Doubling product facings
C By package size
D Among competitors
E Seasonality
171

A certain herbal raw material is used to make Flamin cholagogue. Name this material:

A Сrаtаеgі flores
B Violae herba
C Meliloti herba
D Helichrysi arenarii flores
E Tanaceti flores
172

A pharmaceutical warehouse has received a batch of herbal raw material hawthorn flowers. Merchandise analysis revealed in one of the sacks significant amount of bird-cherry flowers besides the hawthorn. What quality assessment of the herbal raw material should be performed?

A Acceptable admixtures
B Ash values (Total ash)
C Extractive values
D Moisture content
E Mineral admixtures
173

A powder containing a substance with specific weight has been prepared in a pharmacy. Name this substance:

A Bolus alba
B Sodium bicarbonate
C Talcum
D Basic bismuth nitrate
E Sugar
174

Buckthorn bark and its derivative drugs are used as laxatives in medicine. According to the State Pharmacopoeia of Ukraine during chromatographic identification of buckthorn bark it is necessary to detect:

A Glucofrangulins
B Purpurea glycosides
C Ginkgosides
D Lanatosides
E Panaxosides
175

.Weibel's liquid is necessary to stabilize the solution of a certain substance. Name this substance:

A Sodium chloride
B Glucose
C Potassium chloride
D Magnesium sulfate
E Novocaine
176

Strategic planning of pharmaceutical companies consists of several consecutive stages. What stage is the final one?

A Setting goals and tasks
B Strategy assessment
C Analysis of organisation's internal strength and weaknesses
D Environment assessment and analysis
E Choice of strategy
177

What tablet coating protects stomach from harmful influence of active ingredients?

A Intestinally absorbed
B Fat-soluble
C -
D Water-soluble
E Gastrically absorbed
178

A pharmacy supplies the surgical ward of a hospital. What document enables the dispensing chemist to supply the goods:

A Purchase order
B Product revaluation notice
C Report on the movement of packaging
D Consolidated register
E Receipt log book
179

.A68-year-oldman has been prescribed a hypolipidemic agent as a part of his combination therapy for ischemic heart disease. Name this drug:

A Hydrochlorothiazide
B Nifedipine
C Nitroglycerine
D Atorvastatin
E Lisinopril
180

According to the law regulating labour remuneration, the businesses must establish their compensation plan in the following document:

A Collective agreement
B Decree
C Contract of delivery
D Job description
E Statement
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181

If vehicle is not specified, an eye ointment should be prepared with the following sterile vehicle:

A 30 parts of lanolin - 70 parts of vaseline
B 40 parts of anhydrous lanolin - 60 parts of vaseline For Eye Ointments
C 10 parts of anhydrous lanolin - 90 parts of vaseline For Eye Ointments
D Lanolin: vaseline - 1:1
E Vaseline For Eye Ointments
182

What factor enables the extraction of maximum amount of alkaloids from the herbal raw material?

A Preliminary processing of raw materials for their saturation with 96% alcohol
B Intense heating
C Certain value of the solution pH
D Slight heating
E Herbal raw material should be fresh
183

What activity of a pharmaceutical company includes improvement of employees' working and living conditions, healthcare and medical insurance and other means of social development?

A Financial activity
B Social responsibility
C Commercial activity
D Industrial activity
E Charity
184

Complex drug product Urolesan is a litholytic, antispasmodic, and diuretic agent. It contains ethanolic extract of:

A Origanum vulgare
B Matricaria chamomilla
C -
D Rhododendron tomentosum
E Thymus serpyllum
185

To identify pilocarpine hydrochloride it is necessary to use reaction with sodium nitroprusside in an alkaline medium (Legal's test). Resulting cherryred coloring confirms presence of the following in the pilocarpine structure:

A Methylene group
B Methyl group
C Imidazole ring
D Chloride ions
E Lactonic ring
186

When dispensing an antacid and ofloxacin in tablets, the dispensing chemist warned the customer that these drugs should be taken separately with 2hour interval in between. Simultaneous taking of both drugs:

A Decreases ofloxacin absorption
B Increases antacid effectiveness
C Decreases antacid effectiveness
D Increases ofloxacin absorption
E Increases risk of dysbiosis
187

A control laboratory needs to analyze streptomycin powder for injections. To identify it according to the State Pharmacopoeia of Ukraine sodium hydroxide is added into the dissolved powder, the resulting substance is heated, and then iron (III) chloride solution is added, which results in violet coloring of the substance. This test is known as:

A Ninhydrin test
B Vitali-Morin reaction
C Maltol test
D Biuret test
E Thiochrome test
188

A substance was received for analysis. The substance is a round seed 1-1,8 mm in diameter, yellow with bluish tint. When mashed with water, emits characteristic irritant odor; is sharp and acrid to taste. The raw material can be identified as:

A Flax seeds
B Plantago psyllium seeds
C Mustard seeds
D Nigella seeds
E Fenugreek seeds
189

Bank is a financial mediator in pharmacy's payments. Payment of taxes withheld from the employees' salary into budget requires the following document:

A Cash order
B Check payable in account
C Payment order
D Cash register receipts
E Accounting form
190

A powder with a hard to disintegrate substance has been made in a pharmacy. Specify this substance:

A Osarsolum (Acetarsol)
B Sodium chlorides
C Sugar
D Camphor
E Talcum
191

Polyethylene oxide base belongs to the following group:

A Emulsion
B Hydrophobic
C Hydrophilic
D Amphiphilic
E Fat
192

Choose the solvent necessary to prepare concentrated solution of sodium bicarbonate in a pharmacy:

A Ethanol
B Chloroform
C Purified water
D Peach-kernel oil
E Vaseline
193

During storage, suspension instability manifests itself as:

A Sedimentation of particles
B Flocculation of particles
C Dissolution of particles
D Change of particles shape
E Caking of particles
194

Specify the drugs recommended for prevention and correction of dysbiotic problems caused by antibiotic therapy:

A Antacids
B Choleretics
C Uroseptics
D Prokinetics
E Probiotics
195

The documents of a pharmaceutical company are being received and sent in a centralized manner; the documents are stored, drawn-up, registered, and assembled into cases both in the Office Desk of the company and the company's divisions. Specify this type of records management system:

A Decentralized
B Centralized
C Mixed
D Referent
E -
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196

Employees of a wholesale pharmaceutical company have undergone an assessment for their compliance with the requirements of their respective positions. Specify the type of human resources assessment:

A Concurrent
B Preliminary
C Financial
D -
E Concluding
197

In the process of pharmaceutical company entering an offshore market the traditions and customs, religion, system of values, and education level of the local population were analyzed. What factors of international marketing environment were researched?

A Political
B Economical
C Legal
D Sociocultural
E Technological
198

What means of demand stimulation can be applied by pharmacy management among its employees?

A Coupons
B Layout of medical products in shopwindows and on shelves
C In-store advertising
D Bonuses
E -
199

A system of indicators characterizes financial and businesss activity of an organization and the state of its assets and sources on the certain day in the monetary unit. Name this system:

A Turnover balance sheet
B Double entry
C Balance sheet
D Business transactions log book
E Receipts and expenditures report
200

According to the current Ukrainian legislation all drugs are divided into two categories: prescription and nonprescription (over-the-counter). Which one of the listed drugs requires no prescription?

A Tramadol, capsules, 0,05 №10
B Ketamine, 5% infusion solution, 2 ml №10
C Ascorbic acid, 500 mg №30
D Phenobarbital, tablets, 100 mg №6
E Clonidine, ampoules, 1 ml of 0,01% solution №10